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N-Boc-Ethylenediamine

CAS No.
57260-73-8
Chemical Name:
N-Boc-Ethylenediamine
Synonyms
TERT-BUTYL 2-AMINOETHYLCARBAMATE;TERT-BUTYL N-(2-AMINOETHYL)CARBAMATE;(2-AMINO-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER;BOC-EDA;N-Boc-1;Boc-Ethylenediamine;N-BOC-1,2-DIAMINOETHANE;BOC-DIAMINOETHANE;N-boc-1,2-ethylenediamine;N-TERT-BOC-ETHYLENEDIAMINE
CBNumber:
CB4669922
Molecular Formula:
C7H16N2O2
Molecular Weight:
160.21
MDL Number:
MFCD00191871
MOL File:
57260-73-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:05:49

N-Boc-Ethylenediamine Properties

Boiling point 72-80 °C0.1 mm Hg(lit.)
Density 1.012 g/mL at 20 °C(lit.)
refractive index n20/D 1.458(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Oily Liquid
pka 12.40±0.46(Predicted)
Specific Gravity 1.012
color Clear colorless to very light yellow
Water Solubility Miscible with methanol and chloroform. Slightly miscible with water.
Sensitive Air Sensitive
BRN 1932330
Exposure limits ACGIH: TWA 100 ppm
OSHA: TWA 100 ppm(300 mg/m3)
NIOSH: IDLH 1600 ppm; TWA 100 ppm(300 mg/m3); STEL 150 ppm(450 mg/m3)
InChI 1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)
InChIKey AOCSUUGBCMTKJH-UHFFFAOYSA-N
SMILES NCCNC(OC(C)(C)C)=O
CAS DataBase Reference 57260-73-8(CAS DataBase Reference)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 2735 8/PG 3
WGK Germany  3
10-34
Hazard Note  Corrosive/Air Sensitive
HazardClass  8
PackingGroup  III
HS Code  29241990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
REACH Registrations Active
NFPA 704
1
3 0

N-Boc-Ethylenediamine price More Price(103)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 15369 N-Boc-ethylenediamine ≥98.0% (NT) 57260-73-8 1g $153 2026-04-30 Buy
Sigma-Aldrich 15369 N-Boc-ethylenediamine ≥98.0% (NT) 57260-73-8 5g $246 2026-04-30 Buy
TCI Chemical A1371 N-(tert-Butoxycarbonyl)-1,2-diaminoethane >97.0%(GC) 57260-73-8 1g $53 2026-04-30 Buy
TCI Chemical A1371 N-(tert-Butoxycarbonyl)-1,2-diaminoethane >97.0%(GC) 57260-73-8 5g $161 2026-04-30 Buy
Usbiological 262927 N-Boc-ethylenediamine 57260-73-8 25g $340 2026-06-03 Buy
Product number Packaging Price Buy
15369 1g $153 Buy
15369 5g $246 Buy
A1371 1g $53 Buy
A1371 5g $161 Buy
262927 25g $340 Buy

N-Boc-Ethylenediamine Chemical Properties,Uses,Production

Synthesis

Under vigorous stirring at 0°C, Boc₂O (25.0 mM) (100 mL) was dissolved in 100 mL of dichloromethane, and then slowly added dropwise over 3 h to a dichloromethane solution (100 mL) of ethylenediamine (150 mM). The resulting reaction mixture was stirred at room temperature for 16 h. After the reaction was complete, the solvent was evaporated to dryness, and the resulting residue was dissolved in 60 mL of sodium carbonate aqueous solution. The residue was extracted with dichloromethane (2 × 60 mL), the organic layer was dried on anhydrous Na₂SO₄, the desiccant was removed by filtration, and the solvent was evaporated from the resulting filtrate under reduced pressure to obtain the target product molecule N-Boc-Ethylenediamine.


Synthetic route of N-Boc-Ethylenediamine

Figure: Synthetic route of N-Boc-Ethylenediamine

Chemical Properties

Clear colorless to very light yellow oily liquid

Uses

suzuki reaction

Uses

N-Boc-ethylenediamine is used in the synthesis of Thyronamine derivatives and analogs.

Uses

N-Boc-ethylenediamine is used in the synthesis of thyronamine derivatives. It is also used in the preparation of (2-isothiocyanato-ethyl)-carbamic acid tert-butyl ester by reacting with carbon disulfide. Further, it is used in both oligonucleotide and peptide synthesis.

reaction suitability

reagent type: cross-linking reagent

IC 50

Alkyl-Chain

Global( 576)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 472 75
Shanghai Ruiyi Pharmaceutical Technology Co., Ltd 021-54711706 sales5@ruiyitech.com China 224 58
Zepeptide Biotechnology (Shijiazhuang) Co., LTD 13383293380 18032131480 649498984@qq.com China 78 58
Suzhou lipin Chemical Co., Ltd 0512-0512-67509664 19888480046 China 121 58
Nanjing Yuye Biotechnology Co., Ltd. 17826523762 3437309915@qq.com China 81 58
BTC Pharmaceutical CO. Ltd +86-15716293042 15716293042 info@btcpharm.com China 823 55
Porse Fine Chemical Co.,LTD 20-66003216 18666003216 info@porsefinechemical.com China 1964 62
https://www.shachemlin.cn/ 68080707 15021879576 ming-jiao.wu@chemlin.com.cn China 9062 58
Suzhou lipin Chemical Co., Ltd 0512-67509664 19888480046 3516936381@qq.com China 111 58
Shanghai Tuolei Chemical Reagents Co., Ltd. 86-021-50318510 China 67 55

View Lastest Price from N-Boc-Ethylenediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Boc-Ethylenediamine pictures 2026-09-11 N-Boc-Ethylenediamine
57260-73-8
1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
N-Boc-Ethylenediamine  pictures 2026-08-20 N-Boc-Ethylenediamine
57260-73-8
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
N-Boc-Ethylenediamine pictures 2026-06-30 N-Boc-Ethylenediamine
57260-73-8
1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
(2-AMINO-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER 1-BOC-ETHYLENEDIAMINE 1-BOC-AMINO-1,2-ETHANEDIAMINE AKOS 91563 N-TERT-BUTOXYCARBONYL-ETHYLENEDIAMINE N-TERT-BUTYLOXYCARBONYL-ETHYLENEDIAMINE BUTTPARK 27\08-29 BOC-DIAMINOETHANE BOC-NH-(CH2)2-NH2 T-BUTYL N-(2-AMINOETHYL)CARBAMATE RARECHEM AR PA 0020 N-(T-BOC)ETHYLENEDIAMINE N-(TERT-BUTOXYCARBONYL)-1,2-DIAMINOETHANE N-(TERT-BUTOXYCARBONYL)-1,2-ETHYLENEDIAMINE t-butyl 2-aminoethylcarbamate N-Boc-ethylenediamine, 98%, may cont. up to 5% tert-butanol N-Boc-ethylenediMine N-BOC-1,2-diaminoethane,98% Ethane-1,2-diamine, N-BOC protected N-Boc-1,2-diaminoethane, tert-Butyl N-(2-aminoethyl)carbamate N-Boc ethylenediamine LR Grade N-(tert-Butoxycarbonyl)-1,2-ethylenediamin Carbamic acid, N-(2-aminoethyl)-, 1,1-dimethylethyl ester 1,1-DiMethylethyl (2-AMinoethyl)carbaMate N-(2-AMinoethyl)carbaMic Acid 1,1-DiMethylethyl Ester N-(2-Aminoethyl)carbamic Acid tert-Butyl Ester N-Boc-1,2-diaminoethane N-Boc-ethylenediamine N-(tert-Butoxycarbonyl)-1,2-ethylenediamine tert-Butyl N-(2-Aminoethyl)carbamate tert-butyl 2,3-diaMinopropanoate tert-Butyl N-(2-aMiNAethyl)carbaMate Tert-Butyl N-(2-aMinoethyl)carboMate tert-Butyl N-(2-aMinoethyl)car tert-Butyl (2-aminoethyl)carbamate, 1,2-Diaminoethane, N-BOC protected N-BOC-DIAMINOETHANE N-BOC-ETHYLENEDIAMINE N-(2-AMINOETHYL)-N-BOC-AMINE N-(2-AMINOETHYL)CARBAMIC ACID TERT-BUTYL ESTER N-1-T-BUTOXYCARBONYL-1,2-ETHYLENEDIAMINE N-1-T-BUTOXYCARBONYL-1,2-DIAMINOETHANE BOC-1 N-(tert-Butoxycarbonyl)ethylenediamine~tert-Butyl N-(2-aminoethyl)carbamate TERT-BUTYL N-(2-AMINOETHYL)CARBAMATE, 98 % N-BOC-ETHYLNEDIAMINE Carbamic acid, (2-aminoethyl)-, 1,1-dimethylethyl ester (9CI) N-BOC-ETHYLENEDIAME Ethylenediamine, N1-BOC protected N-T-BUTYLOXYCARBONYL-ETHYLENEDIAMINE tert-Butyl N-(2-aminoethyl)carbamate N-tert-Butoxycarbonyl-1,2-diaminoethane N-(2-Aminoethyl)carbamic Acid tert-Butyl Ester tert-butyl 2-aminoethylcarbamate N-(T-BUTYLCARBONYL) ETHYLENEDIAMINE N-BOC-(2-AMINOETHYL)AMINE Boc-EDA, liq. N-T-BOC-1,2- DIAMINOETHANE N-Boc-Ethane-1,2-diamine Mono-(BOC)-ethylene diaMine N-Boc-ethylenediaMine >=98.0% (NT) N-Boc-EthylenediaMine, 95+% N-Boc-ethylenedimin N-Boc-ethylenediamine N-Boc-1,2-ethylenedimine Boc-1,2-diaminoethane