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4-Methoxypicolinaldehyde

4-Methoxypicolinaldehyde Structure
4-Methoxypicolinaldehyde structure
CAS No.
16744-81-3
Chemical Name:
4-Methoxypicolinaldehyde
Synonyms
4-Methoxypyridine-2-carboxaldehyde;4-Methoxypicolinaldehyde;4-Methoxy-2-forMylpyridine;4-Methoxypyridine-2-carbaldehyde;4-Methoxy-2-pyridinecarbaldehyde;4-Methoxy-2-Pyridinecarboxaldehyde;2-Pyridinecarboxaldehyde,4-methoxy-;2-Formyl-4-methoxypyridine, 4-Methoxypicolinaldehyde
CBNumber:
CB4685753
Molecular Formula:
C7H7NO2
Molecular Weight:
137.14
MDL Number:
MFCD08234865
MOL File:
16744-81-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:56
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4-Methoxypicolinaldehyde Properties

Melting point 28-30℃
Boiling point 125-130℃ (25 Torr)
Density 1.159±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 4.47±0.10(Predicted)
Appearance White to yellow Solid-liquid mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280-P271
RIDADR  UN2811
HS Code  2933399990

4-Methoxypicolinaldehyde price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RAA74481 4-Methoxypyridine-2-carboxaldehyde 16744-81-3 10g $354 2026-06-05 Buy
Apolloscientific OR46108 4-Methoxypyridine-2-carboxaldehyde 99% 16744-81-3 100mg $21 2026-06-04 Buy
Apolloscientific OR46108 4-Methoxypyridine-2-carboxaldehyde 99% 16744-81-3 250mg $24 2026-06-04 Buy
Apolloscientific OR46108 4-Methoxypyridine-2-carboxaldehyde 99% 16744-81-3 1g $32 2026-06-04 Buy
Apolloscientific OR46108 4-Methoxypyridine-2-carboxaldehyde 99% 16744-81-3 5g $92 2026-06-04 Buy
Product number Packaging Price Buy
RAA74481 10g $354 Buy
OR46108 100mg $21 Buy
OR46108 250mg $24 Buy
OR46108 1g $32 Buy
OR46108 5g $92 Buy

4-Methoxypicolinaldehyde Chemical Properties, Uses, Production

Synthesis

(4-METHOXY-PYRIDIN-2-YL)-METHANOL

16665-38-6

4-METHOXYPICOLINALDEHYDE

16744-81-3

The general procedure for the synthesis of 4-methoxypyridin-2-aldehyde from (4-methoxypyridin-2-yl)methanol was as follows: - Manganese(IV) oxide (2.412 mL, 139.42 mmol, 4 eq.) was added batchwise to a solution of (4-methoxypyridin-2-yl)methanol (4.85 g, 34.85 mmol, 1 eq.) in ethyl acetate (150 mL). - The reaction mixture was stirred at 80 °C for 2 hours. - Upon completion of the reaction, the hot reaction mixture was filtered through diatomaceous earth. - The filtrate was evaporated to dryness to afford the target product 4-methoxypyridine-2-aldehyde (3.01 g, 21.93 mmol, 62.9% yield). 1H NMR (400.132 MHz, DMSO) δ 3.93 (3H, s), 7.27 (1H, m), 7.44 (1H, d), 8.63 (1H, d), 9.96 (1H, s).

References

[1] Patent: WO2009/56886, 2009, A1. Location in patent: Page/Page column 54
[2] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[3] Inorganic Chemistry, 2013, vol. 52, # 11, p. 6481 - 6501
[4] Bulletin of the Chemical Society of Japan, 2015, vol. 88, # 6, p. 784 - 791
[5] Yakugaku Zasshi, 1957, vol. 77, p. 11,13

4-Methoxypicolinaldehyde synthesis

16665-38-6
16744-81-3
Synthesis of 4-Methoxypicolinaldehyde from (4-Methoxy-pyridin-2-yl)-methanol

4-Methoxypicolinaldehyde Preparation Products And Raw materials

Raw materials

Calcium carbonate N-Bromosuccinimide Potassium carbonate Carbon tetrachloride Sodium Methoxide
Ethyl acetate Di-tert-butyl peroxide Petroleum ether 4-Bromo-2-methylpyridine 2-Pyridinemethanol, 4-(acetyloxy)-, 2-acetate
(4-Chloro-pyridin-2-yl)-methanol 2-Methyl-4-methoxypyridine-N-oxide CHEMPACIFIC 38139 Acetic acid 4-methoxy-pyridin-2-ylmethyl ester (4-Methoxy-pyridin-2-yl)-methanol
4-Methoxy-pyridine-2-carboxylic acid methyl ester 2-Picoline-N-oxide Methyl 4-chloropicolinate

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Preparation Products

4-Methoxypicolinaldehyde Suppliers

Global Suppliers ( 106)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Record Tech (Shanghai) Co., LTD 13761627472 183009664@qq.com China 660 62
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Tianjin Ji Ping Jia Chemical Co., Ltd. 18622448868 jpjchem@163.com China 489 62
Hebei Summedchem Co.,Ltd 0319-5801333-8008 15630992918 sales@summedchem.com China 1000 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Adamas Reagent, Ltd. 59
Shandong Xiya Chemical Co., Ltd 57
Record Tech (Shanghai) Co., LTD 62
Hangzhou Sage Chemical Co., Ltd. 58
SynAsst Chemical. 55
Shanghai Raise Chemical Technology Co.,Ltd 55
Tianjin Ji Ping Jia Chemical Co., Ltd. 62
Hebei Summedchem Co.,Ltd 58

View Latest Price from 4-Methoxypicolinaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methoxy-2-pyridinecarbaldehyde pictures 2020-01-10 4-Methoxy-2-pyridinecarbaldehyde
16744-81-3
 $1.00 1g 95-99% 1ton Career Henan Chemical Co
4-METHOXYPICOLINALDEHYDE pictures 2020-01-09 4-METHOXYPICOLINALDEHYDE
16744-81-3
 $5.50 1KG 98%min 1kg-100kg Career Henan Chemical Co

4-Methoxypicolinaldehyde Spectrum

4-METHOXYPICOLINALDEHYDE(16744-81-3)1HNMR4-METHOXYPICOLINALDEHYDE(16744-81-3)1HNMR

16744-81-3 (4-Methoxypicolinaldehyde) Related Search:

4-Methoxy-2-quinolinecarboxylic acid 4-Methoxy-pyridine-2-carboxylic acid methyl ester Sorafenib 4-Methoxy-pyridine-2-carboxylic acid amide 4-Methoxypicolinaldehyde
4-Methoxypyridine-2-carboxylic acid Dimethyl 4-methoxy-2,6-Pyridinedicarboxylate 4-Methoxy-pyridine-2-carboxylic acid hydrazide 3-Methyl-4-trifluoromethoxy-pyridine-2-carbaldehyde 4-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid
4-Methoxy-pyridine-2-carboxylic acid methyl ester HCl 4-Methoxy-pyridine-2-carboxylic acid hydrochloride 4-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carbaldehyde 3-Methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine-2-carbaldehyde 3-Methyl-4-trifluoromethoxy-pyridine-2-carboxylic acid
4-Ethoxy-3-methyl-pyridine-2-carbaldehyde 4-Methoxy-3-methyl-pyridine-2-carbaldehyde 4-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid methyl ester

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2-Formyl-4-methoxypyridine, 4-Methoxypicolinaldehyde 2-Pyridinecarboxaldehyde,4-methoxy- 4-Methoxypyridine-2-carbaldehyde 4-Methoxy-2-forMylpyridine 4-Methoxy-2-Pyridinecarboxaldehyde 4-Methoxy-2-pyridinecarbaldehyde 4-Methoxypyridine-2-carboxaldehyde 4-Methoxypicolinaldehyde 16744-81-3