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ChemicalBook >> CAS DataBase List >>7-Hydroxy-1,2,3,4-tetrahydroquinoline

7-Hydroxy-1,2,3,4-tetrahydroquinoline

7-Hydroxy-1,2,3,4-tetrahydroquinoline Structure
7-Hydroxy-1,2,3,4-tetrahydroquinoline structure
CAS No.
58196-33-1
Chemical Name:
7-Hydroxy-1,2,3,4-tetrahydroquinoline
Synonyms
Venadaparib Impurity 56;1,2,3,4-Tetrahydro-7-quinolinol;1,2,3,4-Tetrahydro-quinolin-7-ol;7-Quinolinol, 1,2,3,4-tetrahydro-;7-Hydroxy-1,2,3,4-tetrahydroquinoL;7-hydroxy-1,2,3,4-Tetrahydro-quinolin;7-Hydroxy-1,2,3,4-tetrahydroquinoline;7-Hydroxy-1,2,3,4-tetrahydroquinoline1;7-Hydroxy-1,2,3,4-Tetrahydro Quinolinoe;7-Hydroxy-1,2,3,4-tetrahydroquinoline ISO 9001：2015 REACH
CBNumber:
CB7511736
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD08063887
MOL File:
58196-33-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:05:41
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7-Hydroxy-1,2,3,4-tetrahydroquinoline Properties

Melting point 70-80 °C
Boiling point 319.7±31.0 °C(Predicted)
Density 1.141±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
pka 10.70±0.20(Predicted)
form Solid
color Dark Orange to Very Dark Orange
Stability Light Sensitive
InChI InChI=1S/C9H11NO/c11-8-4-3-7-2-1-5-10-9(7)6-8/h3-4,6,10-11H,1-2,5H2
InChIKey HJJRGZMJZDSMDB-UHFFFAOYSA-N
SMILES N1C2=C(C=CC(O)=C2)CCC1
CAS DataBase Reference 58196-33-1(CAS DataBase Reference)
EPA Substance Registry System 7-Quinolinol, 1,2,3,4-tetrahydro- (58196-33-1)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
WGK Germany  WGK 3
TSCA  TSCA listed
HS Code  2933499090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

7-Hydroxy-1,2,3,4-tetrahydroquinoline price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 279812 7-Hydroxy-1,2,3,4-tetrahydroquinoline Asreported 58196-33-1 5g $638 2026-06-03 Buy
Usbiological 279812 7-Hydroxy-1,2,3,4-tetrahydroquinoline Asreported 58196-33-1 10g $914 2026-06-03 Buy
Usbiological 279812 7-Hydroxy-1,2,3,4-tetrahydroquinoline Asreported 58196-33-1 25g $1346 2026-06-03 Buy
Usbiological 279812 7-Hydroxy-1,2,3,4-tetrahydroquinoline Asreported 58196-33-1 50g $1925 2026-06-03 Buy
Usbiological 279812 7-Hydroxy-1,2,3,4-tetrahydroquinoline Asreported 58196-33-1 100g $2683 2026-06-03 Buy
Product number Packaging Price Buy
279812 5g $638 Buy
279812 10g $914 Buy
279812 25g $1346 Buy
279812 50g $1925 Buy
279812 100g $2683 Buy

7-Hydroxy-1,2,3,4-tetrahydroquinoline Chemical Properties, Uses, Production

Synthesis

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

22246-18-0

7-Hydroxy-1,2,3,4-tetrahydroquinoline

58196-33-1

The general procedure for the synthesis of 7-hydroxy-1,2,3,4-tetrahydroquinoline from 3,4-dihydro-7-hydroxy-2(1H)-quinolinone was as follows: 7-hydroxy-3,4-dihydroquinolin-2(1H)-one (2.00 g, 12.26 mmol) was dissolved in tetrahydrofuran (THF, 20 mL) and the solution was cooled down to 0 °C. Subsequently, sodium borohydride (NaBH4, 1.07 g, 28.19 mmol) was added, and then iodine (I2, 3.42 g, 13.48 mmol) dissolved in THF (20 mL) was slowly added dropwise through the addition funnel to the reaction mixture. After installing the condenser, the reaction mixture was refluxed overnight. After completion of the reaction, the reaction mixture was neutralized with 3 M hydrochloric acid solution and then extracted three times with dichloromethane. The organic layers were combined and dried with anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give a viscous yellow oil. Finally, the crude product was purified by fast column chromatography to afford 7-hydroxy-1,2,3,4-tetrahydroquinoline as a white crystalline solid (1.80 g, 98% yield).

References

[1] Angewandte Chemie - International Edition, 2013, vol. 52, # 2, p. 650 - 654
[2] Angew. Chem., 2013, vol. 125, # 2, p. 678 - 682,5
[3] Chinese Chemical Letters, 2018, vol. 29, # 10, p. 1497 - 1499
[4] Organic Letters, 2011, vol. 13, # 23, p. 6196 - 6199
[5] Organic and Biomolecular Chemistry, 2013, vol. 11, # 24, p. 3954 - 3962

7-Hydroxy-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials

Raw materials

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 7-Methoxy-1,2,3,4-tetrahydroquinoline Sodium borohydride Tetrahydrofuran

Preparation Products

7-Methoxy-3,4-dihydro-1H-quinolin-2-one 7-Hydroxyquinoline 1-Ethyl-1,2,3,4-tetrahydroquinoline-7-ol 7-Quinolinol, 1,2,3,4-tetrahydro-1-methyl-

7-Hydroxy-1,2,3,4-tetrahydroquinoline Suppliers

Global Suppliers ( 134)
Supplier Tel Email Country ProdList Advantage
Shanghai joygo pharmacetical tech., Co., Ltd. 13621615409 sale1@joygooo.com China 108 50
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Goodee Pharma Co., Ltd. 0512-62956210 yongyan@goodeepharma.com China 132 60
Wuhan Haizheng Industry & Trade Development Co. Ltd 027-8866 0053/88660577/88660578 China 1070 55
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Supplier Advantage
Shanghai joygo pharmacetical tech., Co., Ltd. 50
Ark Pharm, Inc. 56
Carbott PharmTech Inc. 56
Capot Chemical Co., Ltd 66
Shanghai Longsheng chemical Co.,Ltd. 59
China DongFan Chemical Co.,LTD 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Goodee Pharma Co., Ltd. 60
Wuhan Haizheng Industry & Trade Development Co. Ltd 55
Shanghai Topbiochem Technology Co., Ltd 58

View Latest Price from 7-Hydroxy-1,2,3,4-tetrahydroquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-Hydroxy-1,2,3,4-tetrahydroquinoline pictures 2026-08-20 7-Hydroxy-1,2,3,4-tetrahydroquinoline
58196-33-1
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
7-Hydroxy-1,2,3,4-tetrahydroquinoline pictures 2021-07-13 7-Hydroxy-1,2,3,4-tetrahydroquinoline
58196-33-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
7-Hydroxy-1,2,3,4-tetrahydroquinoline pictures 2021-07-10 7-Hydroxy-1,2,3,4-tetrahydroquinoline
58196-33-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

7-Hydroxy-1,2,3,4-tetrahydroquinoline Spectrum

7-Hydroxy-1,2,3,4-tetrahydroquinoline(58196-33-1)1HNMR7-Hydroxy-1,2,3,4-tetrahydroquinoline(58196-33-1)FT-IR

58196-33-1 (7-Hydroxy-1,2,3,4-tetrahydroquinoline) Related Search:

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7-Hydroxy-1,2,3,4-Tetrahydro Quinolinoe 7-Hydroxy-1,2,3,4-tetrahydroquinoline 7-hydroxy-1,2,3,4-Tetrahydro-quinolin 1,2,3,4-Tetrahydro-quinolin-7-ol 1,2,3,4-Tetrahydro-7-quinolinol 7-Quinolinol, 1,2,3,4-tetrahydro- 7-Hydroxy-1,2,3,4-tetrahydroquinoL 7-Hydroxy-1,2,3,4-tetrahydroquinoline ISO 9001：2015 REACH 7-Hydroxy-1,2,3,4-tetrahydroquinoline1 Venadaparib Impurity 56 58196-33-1