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4-Nitrophenethylamine hydrochloride

4-Nitrophenethylamine hydrochloride Structure
4-Nitrophenethylamine hydrochloride structure
CAS No.
29968-78-3
Chemical Name:
4-Nitrophenethylamine hydrochloride
Synonyms
4-NITROPHENYLETHYLAMINE HYDROCHLORIDE;2-(4-nitrophenyl)ethan-1-aMine hydrochloride;4-NITROPHENYLETHYLAMINE HCL;P-nitrophenyl riMantadine hydrochloride;4-Nitrophcnethylamine;4-NITROPHENYLAMINEHCL;4-NITROPHENETHYLAMINE HCL;Mirabegron Impurity 6 HCl;P-NITROPHENYLETHYLAMINE HCL;Mirabegron EP Impurity E HCl
CBNumber:
CB4775890
Molecular Formula:
C8H11ClN2O2
Molecular Weight:
202.64
MDL Number:
MFCD00012900
MOL File:
29968-78-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:26:37
Request For Quotation

4-Nitrophenethylamine hydrochloride Properties

Melting point 200 °C (dec.)(lit.)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol almost transparency.
form Crystalline Powder
color Yellow to yellow-green
BRN 3568915
Stability Hygroscopic
InChI InChI=1S/C8H10N2O2.ClH/c9-6-5-7-1-3-8(4-2-7)10(11)12;/h1-4H,5-6,9H2;1H
InChIKey JVMHULJEYUQYSH-UHFFFAOYSA-N
SMILES C1([N+]([O-])=O)C=CC(CCN)=CC=1.Cl
CAS DataBase Reference 29968-78-3(CAS DataBase Reference)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  36/37/38-40
Safety Statements  22-24/25-36-26
WGK Germany  3
HS Code  29214990
Storage Class 11 - Combustible Solids
NFPA 704
0
1 0

4-Nitrophenethylamine hydrochloride price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich OTV000173 4-Nitrophenethylamine hydrochloride AldrichCPR 29968-78-3 1g $191 2026-04-30 Buy
Sigma-Aldrich 184802 4-Nitrophenethylamine hydrochloride 95% 29968-78-3 5g $207 2026-04-30 Buy
TCI Chemical N0648 2-(4-Nitrophenyl)ethylamine Hydrochloride >98.0%(HPLC)(T) 29968-78-3 5g $23 2026-04-30 Buy
TCI Chemical N0648 2-(4-Nitrophenyl)ethylamine Hydrochloride >98.0%(HPLC)(T) 29968-78-3 25g $61 2026-04-30 Buy
Usbiological 433248 4-Nitrophenethylamine Hydrochloride 29968-78-3 1g $319 2026-06-03 Buy
Product number Packaging Price Buy
OTV000173 1g $191 Buy
184802 5g $207 Buy
N0648 5g $23 Buy
N0648 25g $61 Buy
433248 1g $319 Buy

4-Nitrophenethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

yellow to brown crystalline powder and chunks

Uses

4-Nitrophenethylamine hydrochloride was used in the synthesis of ortho-metalated primary phenethylamines complexes containing six-membered palladacycles and N-(4-nitrophenethyl)formamide.

Preparation

The preparation of 4-Nitrophenethylamine hydrochloride is as follows:Ten mL of 2M HCl was then added in a one-pot fashion, and, in all cases but threonine, the reaction vessel was heated to 190°Cover 5 min with stirring and then allowed to cool. In the case of the temperature-sensitive threonine, soxhlet extraction with toluene was performed at 80°C to remove R-carvone from the reaction mixture. The aqueous reaction mixture was washed three times with 25 mL of ether, and then water solvent was distilled off from the hydrochloride salt. The hydrochloride salt was transferred to a vacuum oven and dried overnight at 150 °C and 10 Torr.

29968-78-3(1).png

Synthesis

N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE

6270-07-1

4-Nitrophenethylamine hydrochloride

29968-78-3

In a reactor, 140 kg of N-(4-nitrophenylethyl)acetamide was dissolved in 190 kg of ethanol with constant stirring until complete dissolution. The pH of the reaction mixture was adjusted to 1 using 2 mol/L hydrochloric acid solution.Subsequently, the reaction mixture was heated to 80°C and maintained at this temperature for 20 hrs. Upon completion of the reaction, the reaction solution was cooled to room temperature to induce precipitation of the solid product. The crude product was purified by recrystallization through methanol, and after filtration and centrifugation, 116 kg of 4-nitrophenylethylamine hydrochloride was obtained, and the purity of the final product was 99.6%. The yield of this synthesis step was 84.7%.

References

[1] Patent: CN107759477, 2018, A. Location in patent: Paragraph 0063

4-Nitrophenethylamine hydrochloride synthesis

6270-07-1
29968-78-3
Synthesis of 4-Nitrophenethylamine hydrochloride from N-Acetyl-2-(4-nitrophenyl)ethylamine

4-Nitrophenethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Benzene, 1-(2-azidoethyl)-4-nitro- 4-Nitrobenzeneethanol 4-Nitro-3-phenyl-L-alanine N-Acetyl-2-(4-nitrophenyl)ethylamine Propanamide, N-[2-(4-nitrophenyl)ethyl]-
Hydrochloric acid Ethanol Water

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Preparation Products

4-Nitro-phenethylamine (alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride

4-Nitrophenethylamine hydrochloride Suppliers

Global( 521)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Huize Zhongsen Pharmaceutical Technology Co., Ltd. 18519331287 18519331287 1751713684@qq.com China 268 58
Hubei Tuobang Chemical Co., Ltd. 027-59106185 13986192185 1466039@qq.com China 9560 58
Anhui Dexinjia Biopharm Co., Ltd 0531-82375893 15553111391 phoebe@jndxj.com China 285 58
Hangzhou Lenny Technology Co. , Ltd. 571-88086013 sunnie@rdpharm.com China 105 60
Zhangjiagang Xikai Chemical Co.,Ltd 051255701600 13962289590 sales@xikaichem.com China 312 58
Aikon International Limited 17714375163 hywu@aikonchem.com China 9974 58
Shanghai Witofly Chemical Co. ,Ltd. 02150630626 17717886015 sales@witofly.com China 1864 55
Cangzhou Enke Pharma Tech Co.,ltd. 0317-5106596 15533709196 1154424302@qq.com China 2502 58
Ereal Chemical Co., Ltd. 0831-6888461 15181138905 sales@erealchem.com China 88 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Beijing Huize Zhongsen Pharmaceutical Technology Co., Ltd. 58
Hubei Tuobang Chemical Co., Ltd. 58
Anhui Dexinjia Biopharm Co., Ltd 58
Hangzhou Lenny Technology Co. , Ltd. 60
Zhangjiagang Xikai Chemical Co.,Ltd 58
Aikon International Limited 58
Shanghai Witofly Chemical Co. ,Ltd. 55
Cangzhou Enke Pharma Tech Co.,ltd. 58
Ereal Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76

Related articles

View Lastest Price from 4-Nitrophenethylamine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitrophenethylamine hydrochloride pictures 2026-08-20 4-Nitrophenethylamine hydrochloride
29968-78-3
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-Nitrophenethylamine hydrochloride pictures 2026-06-30 4-Nitrophenethylamine hydrochloride
29968-78-3
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Nitrophenethylamine hydrochloride pictures 2026-05-28 4-Nitrophenethylamine hydrochloride
29968-78-3
 $9.00 1KG 99.8% 100tons Hebei Chuanghai Biotechnology Co,.LTD

4-Nitrophenethylamine hydrochloride Spectrum

4-Nitrophenethylamine hydrochloride(29968-78-3)MS4-Nitrophenethylamine hydrochloride(29968-78-3)1HNMR4-Nitrophenethylamine hydrochloride(29968-78-3)13CNMR4-Nitrophenethylamine hydrochloride(29968-78-3)FT-IR4-Nitrophenethylamine hydrochloride(29968-78-3)IR4-Nitrophenethylamine hydrochloride(29968-78-3)Raman

29968-78-3(4-Nitrophenethylamine hydrochloride)Related Search:

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4-NitrophenylethylaMineydrochloride SynonyMs 2-(4-Nitrophenyl)ethylaMine hydrochloride 4- nitrobenzeneethylaMine hydrochloride 4-NitrophenylethylaMine HCl ( SM of Mirabegron ) P-nitrophenyl riMantadine hydrochloride 4-NitrophenylethylaMinehydrochloride SynonyMs 2-(4-Nitrophenyl)ethylaMine hydrochloride β-(p-Nitrophenyl)ethylamine hydrochloride 4-Nitrophenethylamine hydrochloride 95% 4-NITROPHENYLETHYLAMINE HCL 4-NITROPHENYLETHYLAMINE HYDROCHLORIDE 4-NITROPHENETHYLAMINE HCL 4-NITROPHENETHYLAMINE HYDROCHLORIDE 2-(4-Nitrophenyl)ethylaMine hydrochloride, 98+% 2-(P-NITROPHENYL)ETHYLAMINE HYDROCHLORIDE 2-(4-NITROPHENYL)ETHYLAMINE HYDROCHLORIDE 4-Nitrophcnethylamine 4-NITROPHENYLETHYLAMINO HYDROCHLORIDE 4-NITROPHENYLAMINEHCL p-Nitrophenethylamine hydrochloride 2-(4-NITROPHENYL)ETHYLAMINE HYDROCHLORIDE 97+% P-NITROPHENYLETHYLAMINE HCL 2-(4-nitrophenyl) ethylamine, HCl Benzeneethanamine, 4-nitro-, monohydrochloride 2-(4-nitrophenyl)ethanamine hydrochloride 4-NitrophenethylaMine hydrorochloride 4-Nitrophenethylamine hydrochloride,93% Benzeneethanamine,4-nitro-, hydrochloride (1:1) 2-(4-Nitrophenyl)ethylamineHydrochloride> 4-Nitrophenethylamine hydrochloride ISO 9001：2015 REACH -NitrophenylethylaMine hydrochloride Mirabegron Impurity 6 HCl 4-Nitro Phenyl-(ethy-2-amine) 4-nitro-Benzeneethanamine hydrochloride (1:1) 2-(4-Nitrophenyl)ethanamine HCl (NEAH) 4-nitrophenylethylamine hydrochloride (p-nitrophenylethylamine hydrochloride) Mirabegron Intermediate (4-Nitrophenethylamine Hydrochloride) 4-nitrophenyethylamine hydrochloride 4-Nitro phenyl-(ethyl-2-amine).HCl Mirabegron EP Impurity E HCl Coenzyme A Impurity 9 Potassium Salt Mirabeiron Impurity 50(Hydrochloride) 4-Nitrophenethyiaminehydrochloride 2-(4-nitrophenyl) ethan-1-amine Hcl 4-Nitro-benzeneethanamine HCl 2-(4-nitrophenyl)ethan-1-aMine hydrochloride Mirabegron impurity 5 (hydrochloride) 2-(4-Nitrophenyl)Ethanamine Hcl 29968-78-3 C8H10O2N2xHCL O2NC6H4CH2CH2NH2HCl C8H10N2O2CIH C8H10N10O2HCl C8H11ClN2O8 AMINE Amine Salts Building Blocks Nitrogen Compounds Organic Building Blocks Nitro / Nitriles