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ChemicalBook >> CAS DataBase List >>1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Structure
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride structure
CAS No.
16899-81-3
Chemical Name:
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
Synonyms
U 12844A;Isoprenaline impurity A;Norepinephrine Impurity 10;Isoprenaline EP Impurity A;Isoprenaline impurity A CRS;Isoprenaline EP Impurity A HCl;Isoprenaline HCl EP Impurity A;Isoprenaline HCl EP Impurity A HCl;Isoprenaline impurity 1 (hydrochloride);Isoprenaline hydrochloride EP Impurity A
CBNumber:
CB4912824
Molecular Formula:
C11H15NO3.ClH
Molecular Weight:
245.704
MDL Number:
MFCD00035076
MOL File:
16899-81-3.mol
Last updated:2026-05-28 02:23:12
Product description Number Pack Size Price
Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard Y0001577 15 mg $254
3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE AldrichCPR S346322 1 unit $197
Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard Y0001577 y0001577 $220
Isoprenaline impurity A Aldrich S346322 50mg $179
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone Hydrochloride 407913 100mg $418
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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Properties

Melting point 255-257℃
storage temp. 2-8°C
Appearance White to off-white Solid
FDA UNII X4JS3SRV5Y
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001577 Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard 16899-81-3 15 mg $254 2026-04-30 Buy
Sigma-Aldrich S346322 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE AldrichCPR 16899-81-3 1 unit $197 2026-04-30 Buy
Sigma-Aldrich Y0001577 Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard 16899-81-3 y0001577 $220 2024-03-01 Buy
Sigma-Aldrich S346322 Isoprenaline impurity A Aldrich 16899-81-3 50mg $179 2024-03-01 Buy
Usbiological 407913 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone Hydrochloride 16899-81-3 100mg $418 2026-06-03 Buy
Product number Packaging Price Buy
Y0001577 15 mg $254 Buy
S346322 1 unit $197 Buy
Y0001577 y0001577 $220 Buy
S346322 50mg $179 Buy
407913 100mg $418 Buy

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Chemical Properties,Uses,Production

Uses

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.

Preparation

Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride synthesis

99-40-1
16899-81-3
Synthesis of 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride from 2-Chloro-3',4'-dihydroxyacetophenone

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Preparation Products And Raw materials

Raw materials

2-amino-1-(3,4-dihydroxyphenyl)ethan-1-one 2-Chloropropane 2-Chloro-3',4'-dihydroxyacetophenone Catechol Isopropylamine

Preparation Products

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8618017249410 jack.li@time-chemicals.com China 1796 55
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14320 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19935 58
Moxin Chemicals 		+86-17320513646 +86-17320513646 anna@molcoo.com China 9998 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53799 58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd. 		+86-18603013401 jack.lin@sincopharmachem.com China 9999 58
Hubei Molcoo Biotechnology Co., Ltd 18576690171 duxiaoqian@molcoo.com China 4554 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 18652991625 sales@sunlidabio.com China 3223 55
Shandong Boluoda Biological Technology Co., Ltd. 0531-68659041 2310993908@qq.com China 3152 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Supplier Advantage
Shanghai Time Chemicals CO., Ltd. 		55
Standardpharm Co. Ltd. 		58
BOC Sciences 		58
Moxin Chemicals 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd. 		58
Hubei Molcoo Biotechnology Co., Ltd 58
Nanjing Sunlida Biological Technology Co., Ltd. 55
Shandong Boluoda Biological Technology Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Spectrum

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride(16899-81-3)1HNMR

16899-81-3(1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride)Related Search:

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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1) 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride Isoprenaline impurity A [2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE U 12844A 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE Norepinephrine Impurity 10 Isoprenaline EP Impurity A HCl Isoprenaline EP Impurity A Isoprenaline impurity A CRS Isoprenaline HCl EP Impurity A HCl Isoprenaline hydrochloride EP Impurity A Isoprenaline Hydrochloride Impurity 1（Isoprenaline Hydrochloride EP Impurity A） 1-(3,4-dihydroxyphenyl)-2-(isopropyl amino) ethan-1-one Hydrochloride 3，4-dihydroxyphenyl isopropylamino-methyl ketone hydrochloride 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride (Isoprenaline HCl Impurity) 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethan-1-one, hydrochloride (1:1) Isoprenaline HCl EP Impurity A 3',4'-Dihydroxy-2-(isopropylamino)acetophenone hydrochloride 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride - [D92867] Isoprenaline impurity 1 (hydrochloride) Isoprenaline HCl EP Impurity A HCl (Isoproterenol USP Related Compound A) 16899-81-3