ChemicalBook >> CAS DataBase List >>1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
![1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Structure](CAS/GIF/16899-81-3.gif)
- CAS No.
- 16899-81-3
- Chemical Name:
- 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
- Synonyms
- U 12844A;Isoprenaline impurity A;Norepinephrine Impurity 10;Isoprenaline EP Impurity A;Isoprenaline impurity A CRS;Isoprenaline EP Impurity A HCl;Isoprenaline HCl EP Impurity A;Isoprenaline HCl EP Impurity A HCl;Isoprenaline impurity 1 (hydrochloride);Isoprenaline hydrochloride EP Impurity A
- CBNumber:
- CB4912824
- Molecular Formula:
- C11H15NO3.ClH
- Molecular Weight:
- 245.704
- MDL Number:
- MFCD00035076
- MOL File:
- 16899-81-3.mol
Last updated:2026-05-28 02:23:12
| Melting point | 255-257℃ |
|---|---|
| storage temp. | 2-8°C |
| Appearance | White to off-white Solid |
| FDA UNII | X4JS3SRV5Y |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001577 | Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard | 16899-81-3 | 15 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | S346322 | 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE AldrichCPR | 16899-81-3 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001577 | Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard | 16899-81-3 | y0001577 | $220 | 2024-03-01 | Buy |
| Sigma-Aldrich | S346322 | Isoprenaline impurity A Aldrich | 16899-81-3 | 50mg | $179 | 2024-03-01 | Buy |
| Usbiological | 407913 | 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone Hydrochloride | 16899-81-3 | 100mg | $418 | 2026-06-03 | Buy |
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Chemical Properties, Uses, Production
Uses
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.
Preparation
Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).
Synthesis of 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride from 2-Chloro-3',4'-dihydroxyacetophenone
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 63)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Molcoo Biotechnology Co., Ltd | 18274848843 | zhangyu1@molcoo.com | China | 4814 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
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| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 15250997978 | 1511893459@qq.com | China | 4777 | 55 |
| Chengdu Research Accelerators Technology Co., Ltd. | 028-64353063 | reacchemical@163.com | China | 5243 | 58 |
| Shanghai Time Chemicals CO., Ltd. | 021-57951555 | tianshihuagong1111@163.com | CHINA | 1349 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4183 | 58 |
| Guangzhou Dreampharm Biotechnology Co., Ltd. | 020-36607679; 13502246435 | 3008233746@qq.com | China | 9962 | 12 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1)
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride
Isoprenaline impurity A
[2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE
U 12844A
3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
Norepinephrine Impurity 10
Isoprenaline EP Impurity A HCl
Isoprenaline EP Impurity A
Isoprenaline impurity A CRS
Isoprenaline HCl EP Impurity A HCl
Isoprenaline hydrochloride EP Impurity A
Isoprenaline Hydrochloride Impurity 1（Isoprenaline Hydrochloride EP Impurity A）
1-(3,4-dihydroxyphenyl)-2-(isopropyl amino) ethan-1-one Hydrochloride
3，4-dihydroxyphenyl isopropylamino-methyl ketone hydrochloride
1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride (Isoprenaline HCl Impurity)
1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethan-1-one, hydrochloride (1:1)
Isoprenaline HCl EP Impurity A
3',4'-Dihydroxy-2-(isopropylamino)acetophenone hydrochloride
1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride - [D92867]
Isoprenaline impurity 1 (hydrochloride)
Isoprenaline HCl EP Impurity A HCl (Isoproterenol USP Related Compound A)
16899-81-3
