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ChemicalBook >> CAS DataBase List >>2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)-

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)-

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- Structure
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- structure
CAS No.
2125724-38-9
Chemical Name:
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)-
Synonyms
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)-
CBNumber:
CB511455173
Molecular Formula:
C27H25F3N2O4
Molecular Weight:
498.49
MDL Number:
MOL File:
2125724-38-9.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:24
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2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- Properties

Boiling point 519.6±50.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
pka 12.79±0.70(Predicted)

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- Chemical Properties, Uses, Production

Uses

SH498, a novel Bmi-1-mediated antitumor agent, shows potent antiproliferative activity.

References

[1] Yang LF, et al. Synthesis of Cyanoenone-Modified Diterpenoid Analogs as Novel Bmi-1-Mediated Antitumor Agents. ACS Med Chem Lett. 2018 Sep 27;9(11):1105-1110. DOI:10.1021/acsmedchemlett.8b00345

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

2125724-38-9 (2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)-) Related Search:

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- PTC-209 (PTC209 PTC-028 5-fluoro-2-(6-fluoro-2-methyl-1H-benzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine
MS417

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2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- 2125724-38-9