ChemicalBook >> CAS DataBase List >>Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- structure

CAS No.: 2457245-94-0

Chemical Name:: Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

Synonyms: PI3K/Akt/mTOR-IN-3;Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-

CBNumber:: CB511783519

Molecular Formula:: C34H51NO2

Molecular Weight:: 505.77

MDL Number:

MOL File:: 2457245-94-0.mol

MSDS File:: SDS

Last updated:2026-07-27 17:00:41

Request For Quotation

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Properties

Boiling point	615.3±55.0 °C(Predicted)
Density	1.05±0.1 g/cm3(Predicted)
pka	15.89±0.70(Predicted)

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Chemical Properties, Uses, Production

Uses

PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].

References

[1] Wang SS, et al. Synthesis and antitumor activity of α,β-unsaturated carbonyl moiety- containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway. Bioorg Chem. 2020 Aug;101:104036. DOI:10.1016/j.bioorg.2020.104036

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Preparation Products And Raw materials

Raw materials

Preparation Products

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- Suppliers

Global Suppliers ( 2)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	PI3K/Akt/mTOR-IN-3 2457245-94-0	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

PI3K/Akt/mTOR-IN-3
2457245-94-0
$1520.00-2500.00
TargetMol Chemicals Inc.

2457245-94-0 (Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl-) Related Search:

Doxorubicin hydrochloride Ruxolitinib 2-Deoxy-D-glucose Metformin Y-27632

AKT2 Protein, HUMAN (ACTIVE, SF9, GST)

1of2

Olean-12-en-28-amide, 2-methylene-3-oxo-N-2-propen-1-yl- PI3K/Akt/mTOR-IN-3 2457245-94-0