ChemicalBook >> CAS DataBase List >>N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide

CAS No.
2417718-26-2
Chemical Name:
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
Synonyms
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
CBNumber:
CB513461547
Molecular Formula:
C25H19F3N2O
Molecular Weight:
420.43
MDL Number:
MOL File:
2417718-26-2.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Properties

Boiling point 583.3±50.0 °C(Predicted)
Density 1.259±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka 13.30±0.46(Predicted)
form Solid
color White to off-white

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0201468 (R)-VT104 99.93% 2417718-26-2 5mg $336 2026-06-04 Buy
ChemScene CS-0201468 (R)-VT104 99.93% 2417718-26-2 10mg $545 2026-06-04 Buy
aablocks AA0289OG N-[(1R)-1-(pyridin-2-yl)ethyl]-5-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxamide >98% 2417718-26-2 5mg $380 2026-06-02 Buy
aablocks AA0289OG N-[(1R)-1-(pyridin-2-yl)ethyl]-5-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxamide >98% 2417718-26-2 10mg $594 2026-06-02 Buy
Arctom HY-134956B (R)-VT104 99.93% 2417718-26-2 5mg $295 2026-05-26 Buy
Product number Packaging Price Buy
CS-0201468 5mg $336 Buy
CS-0201468 10mg $545 Buy
AA0289OG 5mg $380 Buy
AA0289OG 10mg $594 Buy
HY-134956B 5mg $295 Buy

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Chemical Properties, Uses, Production

Uses

(R)-VT104 is the R-enantiomer of VT104. (R)-VT104 shows an IC50 value of 0.1-1 μΜ for firefly luciferase. VT104 is an orally active and pan-TEAD auto-palmitoylation inhibitor[1].

References

[1] Konradi, Andrei W, et al. Preparation of substituted naphthalene-2-carboxamide derivatives useful for treatment of cancer. WO2020097389.

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide 2417718-26-2