Biofor 389
- CAS No.
- 127245-22-1
- Chemical Name:
- Biofor 389
- Synonyms
- BF 389;Biofor 389;4-[(3,5-di-tert-butyl-4-hydroxyphenyl)methylidene]-2-methyl-1,2-oxazinan-3-one;2H-1,2-Oxazin-3(4H)-one, 4-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-2-methyl-
- CBNumber:
- CB51383587
- Molecular Formula:
- C20H29NO3
- Molecular Weight:
- 331.45
- MDL Number:
- MFCD00902841
- MOL File:
- 127245-22-1.mol
- MSDS File:
- SDS
| Melting point | 171-172 °C |
|---|---|
| Boiling point | 409.2±55.0 °C(Predicted) |
| Density | 1.088±0.06 g/cm3(Predicted) |
| pka | 11.68±0.50(Predicted) |
| FDA UNII | MGJ3XBS5KD |
Biofor 389 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0026863 | BF389 | 127245-22-1 | 1mg | $388 | 2026-06-04 | Buy |
| ChemScene | CS-0026863 | BF389 | 127245-22-1 | 5mg | $968 | 2026-06-04 | Buy |
| ChemScene | CS-0026863 | BF389 | 127245-22-1 | 10mg | $1415 | 2026-06-04 | Buy |
| aablocks | AA00A4M0 | 4-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-2-methyl-2H-1,2-oxazin-3(4H)-one | 127245-22-1 | 1mg | $237 | 2026-05-28 | Buy |
| aablocks | AA00A4M0 | 4-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-2-methyl-2H-1,2-oxazin-3(4H)-one | 127245-22-1 | 5mg | $568 | 2026-05-28 | Buy |
Biofor 389 Chemical Properties, Uses, Production
Uses
BF389 (Biofor 389) is an orally active anti-inflammatory and analesis agent. BF389 is also an inhibitor of cyclooxygenase and 5-lipoxygenase, with IC50s of 4 and 8 ug/mL for COX-1 and COX-2 respectively. BF389 can be used for arthritis research[1][2][3].
in vivo
BF389 (1-30 mg/kg, p.o., five daily oral doses) inhibits paw swelling in rats, with an ED50 of 4.9 mg/kg, indicating the anti-inflammatory activity[1].
IC 50
COX-1: 4 μg/mL (IC50); COX-2: 8 μg/mL (IC50); 5-LOX
References
[1] Bendele AM, et al. Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis. J Pharmacol Exp Ther. 1992 Jan;260(1):300-5. PMID:1309875
[2] Wong S, et al. Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8. DOI:10.1007/BF01987895
[3] Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7. DOI:10.1073/pnas.90.24.11693
Biofor 389 Preparation Products And Raw materials
Raw materials
Preparation Products
Biofor 389 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
View Latest Price from Biofor 389 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-13 | Biofor 389
127245-22-1
|
$156.00-553.00 | 99.71% | 10g | TargetMol Chemicals Inc. |
-
- Biofor 389
127245-22-1
- $156.00-553.00
- 99.71%
- TargetMol Chemicals Inc.
