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ChemicalBook >> CAS DataBase List >>2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Structure
2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE structure
CAS No.
63200-54-4
Chemical Name:
2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE
Synonyms
SW-122;SWF-122;2,4-Dichl;oro-5H-pyrroL;2-d]pyriMidine;o[3,2-d]pyrimidine;4-dichloro-5H-pyrrolo[3;2,6-dichloro-9-deazapurine;2,4-Dichloro-5H-pyrrolo[3...;2,4-Dichloropyrrolo[3,2-d]pyrimidine
CBNumber:
CB5139677
Molecular Formula:
C6H3Cl2N3
Molecular Weight:
188.01
MDL Number:
MFCD08059281
MOL File:
63200-54-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-22 15:57:46
Product description Number Pack Size Price
2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 271152 1g $389
2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 271152 2g $553
2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 271152 5g $814
2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 271152 10g $1168
2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 271152 25g $1763
More product size
Request For Quotation

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Properties

Melting point 226-228 °C(Solv: water (7732-18-5); methanol (67-56-1))
Boiling point 306.2±24.0 °C(Predicted)
Density 1.675±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 10.67±0.40(Predicted)
Appearance White to yellow Solid
InChI InChI=1S/C6H3Cl2N3/c7-5-4-3(1-2-9-4)10-6(8)11-5/h1-2,9H
InChIKey MVTLFDKTYGKJEX-UHFFFAOYSA-N
SMILES C1(Cl)=NC(Cl)=C2NC=CC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933599590

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 271152 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 63200-54-4 1g $389 2026-06-03 Buy
Usbiological 271152 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 63200-54-4 2g $553 2026-06-03 Buy
Usbiological 271152 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 63200-54-4 5g $814 2026-06-03 Buy
Usbiological 271152 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 63200-54-4 10g $1168 2026-06-03 Buy
Usbiological 271152 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine Asreported 63200-54-4 25g $1763 2026-06-03 Buy
Product number Packaging Price Buy
271152 1g $389 Buy
271152 2g $553 Buy
271152 5g $814 Buy
271152 10g $1168 Buy
271152 25g $1763 Buy

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Chemical Properties,Uses,Production

Uses

2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine is an organic intermediate. It can be used to prepare a pyrrolo[3,2-d]pyrimidinone analogue, which is a potent DPP-IV inhibitor that is able to effectively lower blood glucose without causing risks such as weight gain and hypoglycaemia, and achieve prolonged therapeutic control of blood glucose.

Synthesis

1,5-Dihydropyrrolo[3,2-a]pyrimidine-2,4-dion

65996-50-1

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE

63200-54-4

1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (0.38 g, 2.52 mmol) was used as starting material and suspended in phosphorus trichloride (30 mL). The suspension was heated to 120°C and the reaction was carried out for 6 h, during which the mixture gradually changed to a clarified homogeneous solution. Upon completion of the reaction, the mixture was cooled to room temperature and the excess phosphorus trichloride was subsequently removed under vacuum. The residue was cooled in an ice bath and cold ammonium hydroxide solution (30 mL, pH = 8) was slowly added and stirred under this condition for 30 minutes. At the end of the reaction, the precipitate was collected by filtration and washed with cold water. Finally, the resulting solid was dried under vacuum to afford the target product 2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine (0.33 g, 70% yield).

References

[1] Journal of Heterocyclic Chemistry, 1987, vol. 24, p. 821 - 827
[2] Patent: WO2009/62258, 2009, A1. Location in patent: Page/Page column 98
[3] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2113 - 2122
[4] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 15, p. 4354 - 4363
[5] Patent: US2016/257696, 2016, A1. Location in patent: Paragraph 0069-0070

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Preparation Products And Raw materials

Raw materials

5-benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyriMidine 1,5-Dihydropyrrolo[3,2-a]pyrimidine-2,4-dion Ammonia

Preparation Products

2-CHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE 5H-Pyrrolo[3,2-d]pyrimidine, 2-chloro-5-[[2-(trimethylsilyl)ethoxy]methyl]- 4-(2-Chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)morpholine 2-chloro-5-ethyl-3H-pyrrolo[3,2- d]pyrimidin-4(5H)-one 5-benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyriMidine

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Suppliers

Global( 284)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14032 58
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3004 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32998 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 903 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8491 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2949 58
Accela ChemBio Inc. 		+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shanghai Arbor Chemical Co., Ltd. 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Jinan Finer Chemical Co., Ltd 		58
Accela ChemBio Inc. 		58

View Lastest Price from 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE pictures 2026-07-22 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE
63200-54-4
 1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
2,4-Dichloropyrrolo[3,2-d]pyrimidine pictures 2026-07-02 2,4-Dichloropyrrolo[3,2-d]pyrimidine
63200-54-4
 $2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE pictures 2021-07-13 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE
63200-54-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Spectrum

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE(63200-54-4)MS2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE(63200-54-4)1HNMR2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE(63200-54-4)IR12,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE(63200-54-4)IR2

63200-54-4(2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE)Related Search:

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1of4

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE 2,4-Dichloropyrrolo[3,2-d]pyrimidine 2,4-Dichloro-5H-pyrrolo[3... 2-d]pyriMidine 4-dichloro-5H-pyrrolo[3 2,4-Dichl 5H-Pyrrolo[2,3-d]pyriMidine, 2,4-dichloro- 5H-Pyrrolo[3,2-d]pyriMidine,2,4-dichloro- 2,4- twochlorinepyrrolo [3,2-D]pyriMidine 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine 98% o[3,2-d]pyrimidine oro-5H-pyrroL SWF-122 SW-122 2,4-Dichloropyrrole [3,2-D] pyrimidine 2,6-dichloro-9-deazapurine 63200-54-4 Heterocycles Heterocycle-Pyrimidine series CHIRAL CHEMICALS