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Pim-1 kinase inhibitor 10

Pim-1 kinase inhibitor 10 structure

CAS No.: 2918764-57-3

Chemical Name:: Pim-1 kinase inhibitor 10

Synonyms: Pim-1 kinase inhibitor 10;3-Pyridinecarbonitrile, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-1,2-dihydro-6-(3-hydroxyphenyl)-2-oxo-

CBNumber:: CB514285487

Molecular Formula:: C21H13N3O3

Molecular Weight:: 355.35

MDL Number:

MOL File:: 2918764-57-3.mol

Last updated:2025-11-22 08:02:03

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Pim-1 kinase inhibitor 10 Properties

Boiling point	656.538±55.00 °C(Press: 760.00 Torr)(predicted)
Density	1.492±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	7.282±0.10(predicted)

Pim-1 kinase inhibitor 10 Chemical Properties, Uses, Production

Uses

Pim-1 kinase inhibitor 10 (compound 13a) is a both competitive and non-competitive inhibitor of PIM-1/2 kinase. Pim-1 kinase inhibitor 10 can induce cell apoptosis and exhibits anticancer activity. Pim-1 kinase inhibitor 10 also induces caspase 3/7 activation[1].

References

[1] El-Miligy MMM, et, al. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2152810. DOI:10.1080/14756366.2022.2152810

Pim-1 kinase inhibitor 10 Preparation Products And Raw materials

Raw materials

Preparation Products

Pim-1 kinase inhibitor 10 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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Pim-1 kinase inhibitor 10 3-Pyridinecarbonitrile, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-1,2-dihydro-6-(3-hydroxyphenyl)-2-oxo- 2918764-57-3