Ethanolamine hydrochloride
- CAS No.
- 2002-24-6
- Chemical Name:
- Ethanolamine hydrochloride
- Synonyms
- MONOETHANOLAMINE HYDROCHLORIDE;ETHANOLAMINE HCL;ETHANOLAMINE HYDROCH;2-AMINOETHANOL HYDROCHLORIDE;2-Aminoethan-1-ol hydrochloride;meahydrochloride;MONOETHANOLAMINE HCL;ethanolaminechloride;colaminehydrochloride;Ethanolammoniumchlorid
- CBNumber:
- CB5143830
- Molecular Formula:
- C2H8ClNO
- Molecular Weight:
- 97.54
- MDL Number:
- MFCD00012892
- MOL File:
- 2002-24-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 82-84 °C(lit.) |
|---|---|
| Density |
1.07g/cm3 at 20—25°C 1.12g/cm3 at 20—25°C |
| storage temp. | Store below +30°C. |
| solubility | DMSO (Slightly, Heated) |
| form | Agglomerating Crystals |
| Specific Gravity | 1.146 |
| color | White or slightly beige |
| Odor | Odorless |
| PH | 9—10 |
| pka | 9.5(at 25℃) |
| Water Solubility | almost transparency |
| Sensitive | Hygroscopic |
| Merck | 14,3727 |
| BRN | 3542892 |
| Stability | Hygroscopic |
| Cosmetics Ingredients Functions | BUFFERING |
| Cosmetic Ingredient Review (CIR) | ETHANOLAMINE HYDROCHLORIDE (2002-24-6) |
| InChI | 1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H |
| InChIKey | PMUNIMVZCACZBB-UHFFFAOYSA-N |
| SMILES | NCCO.[H]Cl |
| LogP | -1.308 (est) |
| CAS DataBase Reference | 2002-24-6(CAS DataBase Reference) |
| EWG's Food Scores | 1-2 |
| FDA UNII | KKP3YYL02F |
| EPA Substance Registry System | Ethanol, 2-amino-, hydrochloride (2002-24-6) |
| UNSPSC Code | 12352116 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | KJ6370000 | |||||||||
| F | 3-10 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29221100 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Ethanolamine hydrochloride price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.20063 | 2-Hydroxyethylammonium chloride for synthesis | 2002-24-6 | 100G | $43.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | E6133 | Ethanolamine hydrochloride ≥99.0% | 2002-24-6 | 100g | $131 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.20063 | 2-Hydroxyethylammonium chloride for synthesis | 2002-24-6 | 500G | $82.1 | 2026-04-30 | Buy |
| TCI Chemical | A0298 | 2-Aminoethanol Hydrochloride >98.0%(T) | 2002-24-6 | 25g | $32 | 2026-04-30 | Buy |
| TCI Chemical | A0298 | 2-Aminoethanol Hydrochloride >98.0%(T) | 2002-24-6 | 100g | $69 | 2026-04-30 | Buy |
Ethanolamine hydrochloride Chemical Properties, Uses, Production
Chemical Properties
White or slightly beige agglomerating crystals
Uses
Ethanolamine hydrochloride has been used:
- in overnight incubation of the tips to attach primary amine groups at the tip surface
- in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors
- to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process
Biochem/physiol Actions
Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically. It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane. Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia. Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.
Synthesis
141-43-5
2002-24-6
General procedure for the synthesis of ethanolamine hydrochloride from 2-aminoethanol: Reagents and reaction conditions: 36% concentrated hydrochloric acid, room temperature. Operating steps: 1. 15.0 g of 2-aminoethanol was weighed and added to three reaction flasks. 2. 27.0 g of 36% concentrated hydrochloric acid was added dropwise at a constant rate through a dropping funnel under stirring conditions, and the reaction temperature was controlled to be no more than 40 °C. 3. 3. after completion of the dropwise addition, the reaction mixture was continued to be stirred for 20 minutes until the pH was about 2 and the reaction was terminated. 4. remove water from the reaction system by concentration under reduced pressure until a very small amount of water remains. 5. A small amount of toluene was added and the residual water was further removed by azeotropic distillation. 6. The reaction mixture was rapidly cooled to give 23.7 g of a slightly light brown solid product, ethanolamine hydrochloride (M-07), in 99% yield.
Purification Methods
Recrystallise the salt from EtOH. It is deliquescent; store it dry. [Beilstein 4 IV 1406.]
References
[1] Bulletin des Societes Chimiques Belges, 1984, vol. 93, # 10, p. 903 - 912
[2] Patent: CN105585607, 2016, A. Location in patent: Paragraph 0107; 0108; 0109; 0110
[3] Green Chemistry, 2016, vol. 18, # 9, p. 2834 - 2842
[4] Green Chemistry, 2017, vol. 19, # 13, p. 3152 - 3163
Ethanolamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Tengjun Biotechnology Co. LTD | 19821570922 | angela@labgogo.com | China | 9889 | 58 |
| Shandong Jiaoyang Chemical Co., Ltd | 198 1918 9303/18265196555 18265196555 | 27207437@qq.com | China | 85 | 58 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9506 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Latest Price from Ethanolamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | ETHANOLAMINE HYDROCHLORIDE
2002-24-6
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-07-15 | Ethanolamine hydrochloride
2002-24-6
|
$29.00 | 99.73% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | ETHANOLAMINE HYDROCHLORIDE
2002-24-6
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- ETHANOLAMINE HYDROCHLORIDE
2002-24-6
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Ethanolamine hydrochloride
2002-24-6
- $29.00
- 99.73%
- TargetMol Chemicals Inc.
-
- ETHANOLAMINE HYDROCHLORIDE
2002-24-6
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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