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(R)-Omeprazole

(R)-Omeprazole Structure
(R)-Omeprazole structure
CAS No.
119141-89-8
Chemical Name:
(R)-Omeprazole
Synonyms
PRILOSEC;LOSEC;(S)-OMEPRAZOLE;5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE;ANTRA;MEPRAL;ZOLTUM;MOPRAL;OMEPRAL;H 168/68
CBNumber:
CB5160491
Molecular Formula:
C17H19N3O3S
Molecular Weight:
345.42
MDL Number:
MFCD00083192
MOL File:
119141-89-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:48
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(R)-Omeprazole Properties

Melting point >47°C (dec.)
Boiling point 600.0±60.0 °C(Predicted)
Density 1.37±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Sealed in dry,Room Temperature
solubility H2O: 0.5 mg/mL
form solid
pka 8.78±0.10(Predicted)
color white
Stability Hygroscopic
InChI InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m1/s1
InChIKey SUBDBMMJDZJVOS-XMMPIXPASA-N
SMILES C1([S@@](CC2=NC=C(C)C(OC)=C2C)=O)NC2=CC(OC)=CC=C2N=1
FDA UNII S51HU491WJ
NCI Drug Dictionary Prilosec

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DD9087000

(R)-Omeprazole price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 464051 (R)-Omeprazole 119141-89-8 1mg $523 2026-06-03 Buy
Biosynth FO165430 (R)-Omeprazole 119141-89-8 5mg $900 2026-06-04 Buy
Biosynth FO165430 (R)-Omeprazole 119141-89-8 2mg $900 2026-06-04 Buy
Biosynth FO165430 (R)-Omeprazole 119141-89-8 1mg $900 2026-06-04 Buy
Biosynth FO165430 (R)-Omeprazole 119141-89-8 10mg $1298 2026-06-04 Buy
Product number Packaging Price Buy
464051 1mg $523 Buy
FO165430 5mg $900 Buy
FO165430 2mg $900 Buy
FO165430 1mg $900 Buy
FO165430 10mg $1298 Buy

(R)-Omeprazole Chemical Properties, Uses, Production

Uses

R-Form of Omeprazole. Gastric proton-pump inhibitor

Uses

(R)-Omeprazole is the R-enantiomer of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.

Definition

ChEBI: A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has R configuration at the sulfur atom.

Synthesis

Ufiprazole

73590-85-9

OMEPRAZOLE

119141-89-8

GENERAL STEPS: Sulfide (5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]benzimidazole, 100 mmol) and titanium-tannic acid catalyst (1.1 mmol) were dissolved in ethyl acetate (EtOAc, 6.0 mL). The reaction mixture was kept at a constant temperature to the indicated temperature (usually 0°C, or in the range of -20 to +20°C for variable temperature experiments). Subsequently, a 30% aqueous hydrogen peroxide solution (0.105 mmol H2O2) was added all at once. The reaction mixture was continuously stirred at 500 rpm at a constant temperature (usually 24 h). For low-temperature experiments, the reaction time was about 30 h at -10 °C, which could be extended to 10 days at -20 °C. To analyze the progress of the reaction, 20 μL of the reaction mixture was taken into a vial and immediately evaporated carefully to dryness (~15-20 s) with a stream of compressed air. The residual solid was dissolved in isopropanol solution (0.20 mL) containing 1% triethylamine (Et3N), and the residual sulfide, (R)- and (S)-sulfoxide, and sulfone contents were analyzed by chiral HPLC.

References

[1] Catalysis Today, 2017, vol. 279, p. 84 - 89
[2] Heterocyclic Communications, 2016, vol. 22, # 1, p. 17 - 19
[3] Patent: US2008/319195, 2008, A1. Location in patent: Page/Page column 5
[4] Patent: US9228216, 2016, B2. Location in patent: Page/Page column 50-52
[5] Journal of Organic Chemistry, 2018, vol. 83, # 14, p. 7453 - 7458

(R)-Omeprazole Preparation Products And Raw materials

Raw materials

Ammonium thiocyanate Erythromycin Esomeprazole Ufiprazole Ethyl acetate
Hydrogen peroxide

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Preparation Products

(R)-Omeprazole Suppliers

Global Suppliers ( 126)
Supplier Tel Email Country ProdList Advantage
Zhongxin Chenshi (Wuhan) Technology Co., Ltd 18942922096 2662561040@qq.com China 980 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1934 58
Henan Kangsheng New Materials Co., LTD 18971085384 183320562@qq.com China 114 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603 China 4484 50
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1949 55
Eastbang Pharmaceuticals Technology Co., Ltd. +86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387 China 454 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Supplier Advantage
Zhongxin Chenshi (Wuhan) Technology Co., Ltd 58
Hefei fuya biotechnology co. LTD 58
Henan Kangsheng New Materials Co., LTD 58
J & K SCIENTIFIC LTD. 76
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Cato Research Chemicals Inc. 55
Eastbang Pharmaceuticals Technology Co., Ltd. 58
Quality Control Solutions Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58

View Latest Price from (R)-Omeprazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Omeprazole Impurity 25 pictures 2026-03-12 Omeprazole Impurity 25
119141-89-8
 10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
OMEPRAZOLE pictures 2019-07-06 OMEPRAZOLE
119141-89-8
 $1.00 1KG 99% 1000KG Career Henan Chemical Co

119141-89-8 ((R)-Omeprazole) Related Search:

5-Methoxybenzimidazole 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole 4sodium 2-(((3,5-dimethyl-4-oxidopyridin-2-yl)methyl)sulfinyl)-5-methoxybenzo[d]imidazol-1-ide Loxoprofen Impurity 34 Esomeprazole hemistrontium
1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-

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ZOLTUM 6-methoxy-2-[(R)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole Omeprazole Impurity N R-Omeparazole Esomeprazole Sodium Impurity 15 Omeprazole Impurity 33 omeprazole impurity B (r-omeprazole) Omeprazole impurity 18/(R)-Omeprazole/(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole MEPRAL LOSEC H 168/68 GASTROGARD GASTROLOC ANTRA 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE Erythromycine Thiocynate (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole R-(+)-OMEPRAZOLE OMEPRAL MOPRAL (R)-6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole Esomeprazole EP Impurity F 1H-BenziMidazole,6-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]- 5-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]sulfinyl]-1H-benziMidazole EsoMeprazole iMpurity F Omeprazole impurity N (R)-Omeprazole Omeprazole R-Isomer (+)-omeprazole (R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole (Esomeprazole Impurity） Omeprazole Impurity N (Esomeprazole-magnesium EP Impueity F) Esomeprazole Impurity 6 Monomer Esomeprazole magnesium dihydrate EP Impurity F Trimethoprim Impurity 17 Esomeprazole magnesium EP Impurity F (R)-Esomeprazole (S)-OMEPRAZOLE PRILOSEC 119141-89-8 Cell Biology Cell Signaling and Neuroscience BioChemical Voltage-gated Ion Channels Potassium Channel Modulators Ion Channels Monovalent Ion Channels Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals