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Etamsylate

Etamsylate structure

CAS No.: 2624-44-4

Chemical Name:: Etamsylate

Synonyms: ETHAMSYLATE;e141;Phenolsulfonate;md141;eselin;HeMsyl;K-Stat;Sylate;altodor;aglumin

CBNumber:: CB5165128

Molecular Formula:: C10H17NO5S

Molecular Weight:: 263.31

MDL Number:: MFCD00867499

MOL File:: 2624-44-4.mol

Last updated:2025-09-26 17:40:57

Product description	Number	Pack Size	Price
Etamsylate European Pharmacopoeia (EP) Reference Standard	E1830000	10 mg	$156
Etamsylate European Pharmacopoeia (EP) Reference Standard	E1830000	e1830000	$153
Etamsylate >98.0%(HPLC)(T)	E1145	1g	$30
Etamsylate >98.0%(HPLC)(T)	E1145	5g	$89
Ethamsylate	E889950	10mg	$55
More product size

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Etamsylate Properties

Melting point	125°
Density	1.3441 (rough estimate)
refractive index	1.5060 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
form	Solid
color	White to Pale Red
Merck	14,3722
Stability	Hygroscopic
InChI	InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
InChIKey	HBGOLJKPSFNJSD-UHFFFAOYSA-N
SMILES	C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC
CAS DataBase Reference	2624-44-4(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	24YL531VOH
ATC code	B02BX01
EPA Substance Registry System	Ethamsylate (2624-44-4)
UNSPSC Code	41116107
NACRES	NA.77

Pharmacokinetic data

Protein binding	>90%
Excreted unchanged in urine	72-80%
Biological half-life	3.7-8 / -

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501
RTECS	DB6145000
HS Code	2921.19.6190
HazardClass	IRRITANT
Toxicity	LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)

Etamsylate price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E1830000	Etamsylate European Pharmacopoeia (EP) Reference Standard	2624-44-4	10 mg	$156	2025-07-31	Buy
Sigma-Aldrich	E1830000	Etamsylate European Pharmacopoeia (EP) Reference Standard	2624-44-4	e1830000	$153	2024-03-01	Buy
TCI Chemical	E1145	Etamsylate >98.0%(HPLC)(T)	2624-44-4	1g	$30	2025-07-31	Buy
TCI Chemical	E1145	Etamsylate >98.0%(HPLC)(T)	2624-44-4	5g	$89	2025-07-31	Buy
TRC	E889950	Ethamsylate	2624-44-4	10mg	$55	2021-12-16	Buy

Product number	Packaging	Price	Buy
E1830000	10 mg	$156	Buy
E1830000	e1830000	$153	Buy
E1145	1g	$30	Buy
E1145	5g	$89	Buy
E889950	10mg	$55	Buy

Etamsylate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Haemostatic / Anti Coagulant

Uses

Hemostatic;prostaglandin synthesis inhibitor

Definition

ChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.

Biological Activity

Etamsylate is a haemostatic agent th at is used for the management of blood loss. Apparently etamsylate increases capillary wall resistance and platelet adhesives by inhibition of the biosynthesis of prostaglandins causing platelet disaggregation in a presence of vascular wound. Recent studies suggest th at etamsylate antagonizes anti-coagulant activity of heparin.

Mechanism of action

Etamsylate is an antihaemorrhagic and vasoprotective agent. It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss.

Clinical Use

Short-term treatment of blood loss in menorrhagia
Prophylaxis of surgical bleeding (unlicensed)

Side effects

Significant: Hypotension (parenteral). Rarely, severe hypersensitivity reaction, including anaphylaxis.
Blood and lymphatic system disorders: Parenteral: Rarely, neutropenia, agranulocytosis, thrombocytopenia.
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain or discomfort.
General disorders and administration site conditions: Asthenia (parenteral). Rarely, fever.
Musculoskeletal and connective tissue disorders: Rarely, arthralgia.
Nervous system disorders: Headache.
Skin and subcutaneous tissue disorders: Rash.
Vascular disorders: Rarely, thromboembolism (parenteral).

Metabolism

Etamsylate is excreted unchanged, mainly in the urine.

Etamsylate synthesis

Synthesis of Etamsylate from 2,5-dihydroxybenzenesulphonic acid and Diethylamine

Etamsylate Preparation Products And Raw materials

Raw materials

Sulfur dioxide Diethylamine Diethylaminoethanol 1,4-Benzoquinone

Preparation Products

Etamsylate Suppliers

Global( 501)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Suikang Pharmaceutical Co.,Ltd.	+86-18239973690	sales@suikangpharm.com	China	311	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8772	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12247	58
shandong perfect biotechnology co.ltd	+86-53169958659 +86-13153181156	sales@sdperfect.com	China	294	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Wuhan Quanjinci New Material Co.,Ltd.	+86-15271838296; +8615271838296	kyra@quanjinci.com	China	1512	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Apeloa production Co.,Limited	+8619933239880	admin@apcl.com.cn	China	861	58

Supplier	Advantage
Henan Suikang Pharmaceutical Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
shandong perfect biotechnology co.ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Wuhan Quanjinci New Material Co.,Ltd.	58
airuikechemical co., ltd.	58
Apeloa production Co.,Limited	58

View Lastest Price from Etamsylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-15	Etamsylate 2624-44-4	US $0.00 / Kg/Drum	25KG	99.0%~101.0%; BP2010	50tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-10-15	Etamsylate 2624-44-4	US $5.00-0.50 / KG	0.10000000149011612KG	99% hplc	5000kg	Wuhan JiyunZen Tech Co., Ltd.
2025-10-11	Etamsylate 2624-44-4	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

Etamsylate
2624-44-4
US $0.00 / Kg/Drum
99.0%~101.0%; BP2010
WUHAN FORTUNA CHEMICAL CO., LTD

Etamsylate
2624-44-4
US $5.00-0.50 / KG
99% hplc
Wuhan JiyunZen Tech Co., Ltd.

Etamsylate
2624-44-4
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Etamsylate Spectrum

Etamsylate(2624-44-4)¹HNMR

2624-44-4(Etamsylate)Related Search:

Calcium dobesilate Amlodipine Besylate Sulfanilic acid Ethylamine Glycine

Benzenesulfonic acid Dodecylbenzenesulphonic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Diethylamine hydrochloride

ETAMSYLATE FOR INJECTION Diethylamine PHENOLSULFONIC ACID Etamsylate ETAMSYLATE EPE(CRM STANDARD)

phosphoric acid

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altodor e141 eselin md141 2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine 2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1) 2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine 2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine aglumin ciclonamina cyclonamine dicynene dicynone diethylammonium2,5-dihydroxybenzenesulfonate diethylammoniumcyclohexadien-4-ol-1-one-4-sulfonate diidroxi-1,4-benzenesulfonato-3-di-etilammonium ETAMSYLATE ETHAMSYLATE diethylammonium 2,5-dihydroxybenzenesulphonate Diethylammonium cyclohexadiene-4-ol-1-one-4-sulfonate 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine N,N-Diethylamine-2,5-dihydroxybenzolsulphonate 2,5-Dihydroxybenzenesulfonic acid diethylamine salt Benzenesulfonic acid, 2,5-dihydroxy-, compd. with diethylamine Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1) Eselin【hemostatic】 diethylaMine 2,5-dihydroxybenzenesulfonate 1-hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonicacidcompd.withdiethylamine EtaMsylate,(S) 2,5-Dihydroxybenzenesulfonic Acid N-EthylethanaMine Salt Biosinon Dicinone HeMsyl K-Stat Sylate EtaMsvlatuM 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1) Phenolsulfonate fenhuangyian Etamsylate CRS Etamsylate> Etamsylate USP/EP/BP Etamsylater sulfoethylamine EtamsylateQ: What is Etamsylate Q: What is the CAS Number of Etamsylate Q: What is the storage condition of Etamsylate Q: What are the applications of Etamsylate Etamsylate API 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamin Phenolsulfoethylamine tysamine Methanesulfonic Acid Impurity 8 Ethamsylate, 10 mM in DMSO Etamsylate 100 μg/mL in Acetonitrile 2624-44-4 Other APIs For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc API Amines Aromatics