6-Fluoro-1H-indole-3-carboxylic acid
- CAS No.
- 23077-44-3
- Chemical Name:
- 6-Fluoro-1H-indole-3-carboxylic acid
- Synonyms
- OTAVA-BB 1149596;RARECHEM AL BE 0955;UKRORGSYN-BB BBV-5127372;6-Fluoro-indole-3-carboxylic acid;Indole-3-carboxylic acid, 6-fluoro-;6-Fluoro-1H-indole-3-carboxylic acid;1H-Indole-3-carboxylic acid, 6-fluoro-
- CBNumber:
- CB5197848
- Molecular Formula:
- C9H6FNO2
- Molecular Weight:
- 179.15
- MDL Number:
- MFCD06203359
- MOL File:
- 23077-44-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| RIDADR | UN2811 |
| HS Code | 2933998090 |
6-Fluoro-1H-indole-3-carboxylic acid price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC906871 | 6-Fluoro-1H-indole-3-carboxylic acid 98% | 23077-44-3 | 250mg | $86 | 2026-06-04 | Buy |
| Apolloscientific | PC906871 | 6-Fluoro-1H-indole-3-carboxylic acid 98% | 23077-44-3 | 1g | $135 | 2026-06-04 | Buy |
| Apolloscientific | PC906871 | 6-Fluoro-1H-indole-3-carboxylic acid 98% | 23077-44-3 | 5g | $373 | 2026-06-04 | Buy |
| Matrix Scientific | 089646 | 6-Fluoroindole-3-carboxylic acid | 23077-44-3 | 250.00mg | $158 | 2026-05-18 | Buy |
| Matrix Scientific | 089646 | 6-Fluoroindole-3-carboxylic acid | 23077-44-3 | 1.00g | $395 | 2026-05-18 | Buy |
6-Fluoro-1H-indole-3-carboxylic acid Chemical Properties, Uses, Production
Synthesis
399-51-9
407-25-0
23077-44-3
Trifluoroacetic anhydride (9.009 mL, 64.8 mmol, 2.2 eq.) was added slowly and dropwise to a stirred solution of 6-fluoroindole (4.000 g, 29.6 mmol, 1.0 eq.) dissolved in DMF (25 mL) at 0 °C (temperature controlled using an external ice bath). After the reaction mixture was kept in the ice bath for 3 h, the reaction was quenched with 40 mL of 2N sodium carbonate solution. The precipitate was collected by filtration and washed with distilled water. The resulting solid was dissolved in 4 M NaOH solution (50 mL) and refluxed for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and poured into 50 mL of distilled water. The mixture was cooled again in an ice bath and the pH was adjusted slowly by adding 6N HCl to 3. The precipitate precipitated was collected by filtration, washed with distilled water and dried under vacuum to give the off-white solid product 6-fluoro-1H-indole-3-carboxylic acid (3.5 g, 66% yield).
References
[1] Patent: WO2017/197177, 2017, A1. Location in patent: Paragraph 0219-0221
[2] ChemMedChem, 2012, vol. 7, # 11, p. 1915 - 1920
6-Fluoro-1H-indole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
6-Fluoro-1H-indole-3-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Devinchem Ltd | 027-65318838 13646286950 | sales@devinchem.com | China | 2996 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Watson Biotechnology Co.,Ltd | 027-59207879 1972026995 18140587686 | sales@3600chem.com | China | 4193 | 55 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from 6-Fluoro-1H-indole-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 6-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID
23077-44-3
|
$6.60 | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
-
- 6-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID
23077-44-3
- $6.60
- 97%-99%
- Career Henan Chemical Co
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