6-Fluoroindole-3-carboxaldehyde
- CAS No.
- 2795-41-7
- Chemical Name:
- 6-Fluoroindole-3-carboxaldehyde
- Synonyms
- 6-FLUOROINDOLE-3-ALDEHYDE;6-Fluoro-3-formyl-1H-indole;1H6-FLUOROINDOLE-3-ALDEHYDE;6-FLUOROINDOLE-3-CARBALDEHYDE;6-Fluoroindole-3-carboxaldehyde;6-fluoro-1H-indole-3-carbaldehyde;1H-6-FLUOROINDOLE-3-CARBOXALDEHYDE;6-Fluoro-1H-indole-3-carboxaldehyde;6-Fluoroindole-3-carboxaldehyde,98%;6-Fluoroindole-3-carboxaldehyde ,97%
- CBNumber:
- CB9305232
- Molecular Formula:
- C9H6FNO
- Molecular Weight:
- 163.15
- MDL Number:
- MFCD00069703
- MOL File:
- 2795-41-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 174-178°C |
|---|---|
| Boiling point | 342.4±22.0 °C(Predicted) |
| Density | 1.385±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in methanol. |
| form | crystalline |
| pka | 14.90±0.30(Predicted) |
| color | yellow |
| CAS DataBase Reference | 2795-41-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P305+P351+P338-P261-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
6-Fluoroindole-3-carboxaldehyde price More Price(78)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 234715 | 6-Fluoroindole-3-carboxaldehyde 98+% (HPLC) ≥98%(HPLC) | 1g | $215 | 2026-06-03 | Buy | |
| Usbiological | 234715 | 6-Fluoroindole-3-carboxaldehyde 98+% (HPLC) ≥98%(HPLC) | 5g | $435 | 2026-06-03 | Buy | |
| Usbiological | 234715 | 6-Fluoroindole-3-carboxaldehyde 98+% (HPLC) ≥98%(HPLC) | 25g | $1231 | 2026-06-03 | Buy | |
| Biosynth | FF30379 | 6-Fluoroindole-3-carboxaldehyde | 2795-41-7 | 25g | $150 | 2026-06-04 | Buy |
| Biosynth | FF30379 | 6-Fluoroindole-3-carboxaldehyde | 2795-41-7 | 10g | $150 | 2026-06-04 | Buy |
6-Fluoroindole-3-carboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
Yellow crystal
Uses
6-Fluoroindole-3-carboxaldehyde is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Synthesis
399-51-9
68-12-2
2795-41-7
GENERAL STEPS: Oxalyl chloride (0.3 mL) was slowly added dropwise to cooled (ice bath) N,N-dimethylformamide (3 mL) under stirring conditions. The reaction mixture was stirred continuously at 0 °C for 1 hour. Subsequently, 6-fluoroindole (4 mmol) was dissolved in N,N-dimethylformamide (1.5 mL) and the resulting solution was added slowly dropwise to the above reaction mixture. The reaction system was stirred at room temperature for 5 hours. Upon completion of the reaction, 2 N sodium hydroxide solution (2 mL) was added and the mixture was heated to 100 °C and held for 10 minutes. The reaction solution was cooled and extracted with ethyl acetate (3 x 50 mL). The organic phases were combined and washed sequentially with water and saturated brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography with the eluent of ethyl acetate/petroleum ether (3:1, v/v) to obtain pure 6-fluoroindole-3-carbaldehyde.
References
[1] Journal of the American Chemical Society, 2009, vol. 131, # 31, p. 10796 - 10797
[2] European Journal of Medicinal Chemistry, 2013, vol. 65, p. 158 - 167
[3] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 10, p. 3307 - 3312
[4] Journal of Enzyme Inhibition and Medicinal Chemistry, 2011, vol. 26, # 2, p. 261 - 269
[5] Patent: CN103664895, 2018, B. Location in patent: Paragraph 0124-0126
6-Fluoroindole-3-carboxaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Nanjing Habo Medical Technology Co., Ltd. | 13376080562 13376090521 | sales@habotech.com | China | 726 | 60 |
View Lastest Price from 6-Fluoroindole-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-06-02 | 6-Fluoroindole-3-carboxaldehyde in stock Factory
2795-41-7
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2020-01-08 | 6-FLUOROINDOLE-3-CARBOXALDEHYDE
2795-41-7
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 6-Fluoroindole-3-carboxaldehyde in stock Factory
2795-41-7
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 6-FLUOROINDOLE-3-CARBOXALDEHYDE
2795-41-7
- $3.00
- 98%
- Career Henan Chemical Co
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