6,7,8-Trimethoxycoumarin
- CAS No.
- 6035-49-0
- Chemical Name:
- 6,7,8-Trimethoxycoumarin
- Synonyms
- Di-O-Methylfraxetin;BG8;BG 8;BG-8;DIMETHYLFRAXETIN;O,O-DIMETHYLFRAXETIN;DIMETHYLFRAXETIN, O,O-;Dimethylfraxetin, >99%;Fraxetin dimethyl ether;6,7,8-Trimethoxycoumarin
- CBNumber:
- CB5237142
- Molecular Formula:
- C12H12O5
- Molecular Weight:
- 236.22
- MDL Number:
- MFCD00145039
- MOL File:
- 6035-49-0.mol
- MSDS File:
- SDS
| Melting point | 104-105°C |
|---|---|
| Boiling point | 338.68°C (rough estimate) |
| Density | 1.249 |
| refractive index | 1.5140 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming) |
| form | Cryst. |
| color | White to yellow |
| biological source | plant |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| InChI | InChI=1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3 |
| InChIKey | RAYQKHLZHPFYEJ-UHFFFAOYSA-N |
| SMILES | C1(=O)OC2=C(OC)C(OC)=C(OC)C=C2C=C1 |
| UNSPSC Code | 12352205 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-45 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 29322090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
6,7,8-Trimethoxycoumarin price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36485 | Dimethylfraxetin ≥98% | 6035-49-0 | 1mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 36485 | Dimethylfraxetin ≥98% | 6035-49-0 | 5mg | $141 | 2026-04-30 | Buy |
| Cayman Chemical | 36485 | Dimethylfraxetin ≥98% | 6035-49-0 | 10mg | $244 | 2026-04-30 | Buy |
| Cayman Chemical | 36485 | Dimethylfraxetin ≥98% | 6035-49-0 | 25mg | $468 | 2026-04-30 | Buy |
| Usbiological | 300192 | Dimethylfraxetin (Di-O-methylfraxetin) ≥98% | 6035-49-0 | 20mg | $462 | 2026-06-03 | Buy |
6,7,8-Trimethoxycoumarin Chemical Properties, Uses, Production
Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.
Uses
Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.
Definition
ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.
Biological Activity
Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.
in vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .
target
Ki: 0.0097 μM (Carbonic anhydrase)
6,7,8-Trimethoxycoumarin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Shenzhen Sungening Bio-Tech Co., Ltd | +86-0755-89668383 | sales@sungening.com | China | 1319 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Chengdu Climax Biotech Co., Ltd. | 028-83311324 1278112614 | climaxbiotech@gmail.com | China | 925 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
View Latest Price from 6,7,8-Trimethoxycoumarin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 6,7,8-TRIMETHOXYCOUMARIN
6035-49-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-07-27 | Dimethylfraxetin
6035-49-0
|
$35.00-136.00 | 99.95% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | 6,7,8-Trimethoxycoumarin
6035-49-0
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- 6,7,8-TRIMETHOXYCOUMARIN
6035-49-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Dimethylfraxetin
6035-49-0
- $35.00-136.00
- 99.95%
- TargetMol Chemicals Inc.
-
- 6,7,8-Trimethoxycoumarin
6035-49-0
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
