- Dimethylfraxetin
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- $35.00
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2026-07-27
- CAS:6035-49-0
- Purity: 99.95%
- Supply Ability: 10g
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| | 6,7,8-Trimethoxycoumarin Basic information |
| Product Name: | 6,7,8-Trimethoxycoumarin | | Synonyms: | O,O-DIMETHYLFRAXETIN;DIMETHYLFRAXETIN, O,O-(RG);DIMETHYLFRAXETIN;DIMETHYLFRAXETIN, O,O-;6,7,8-Trimethoxy-2H-1-benzopyran-2-one;Fraxetin dimethyl ether;Dimethylfraxetin, >99%;CouMarin, 6,7,8-triMethoxy- | | CAS: | 6035-49-0 | | MF: | C12H12O5 | | MW: | 236.22 | | EINECS: | 200-485-9 | | Product Categories: | Coumarins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 6035-49-0.mol |  |
| | 6,7,8-Trimethoxycoumarin Chemical Properties |
| Melting point | 104-105°C | | Boiling point | 338.68°C (rough estimate) | | density | 1.249 | | refractive index | 1.5140 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming) | | form | Cryst. | | color | White to yellow | | biological source | plant | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | InChI | InChI=1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3 | | InChIKey | RAYQKHLZHPFYEJ-UHFFFAOYSA-N | | SMILES | C1(=O)OC2=C(OC)C(OC)=C(OC)C=C2C=C1 |
| Risk Statements | 22 | | Safety Statements | 22-45 | | WGK Germany | WGK 3 | | HS Code | 29322090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 6,7,8-Trimethoxycoumarin Usage And Synthesis |
| Chemical Properties | White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb. | | Uses | Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects. | | Definition | ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins. | | Biological Activity | Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM. | | in vitro | At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study . | | target | Ki: 0.0097 μM (Carbonic anhydrase) |
| | 6,7,8-Trimethoxycoumarin Preparation Products And Raw materials |
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