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4,4'-Methylenebis(2,6-dimethylaniline)

CAS No.
4073-98-7
Chemical Name:
4,4'-Methylenebis(2,6-dimethylaniline)
Synonyms
4,4'-Methylenebis;4,4'-methylenebis(2,6-xylidine);AURORA KA-6230;enebis(2,6-dimethyL;LABOTEST-BB LT00160072;4,4'-METHYLENEDI-2,6-XYLIDINE;4-(4-Amino-3,5-dimethylbenzyl);4,4'-Methylenebis(2,6-dimethylaniline);4,4'-Methylenebis(2,6-dimethylaniline);4,4'-Methylenebis(2,6-dimethylbenzenamine)
CBNumber:
CB5273555
Molecular Formula:
C17H22N2
Molecular Weight:
254.37
MDL Number:
MFCD00058680
MOL File:
4073-98-7.mol
MSDS File:
SDS
Last updated:2026-05-28 05:25:59
Product description Number Pack Size Price
4,4′-Methylenebis(2,6-dimethylaniline) 99% 360791 5g $50.7
4,4'-Methylenebis(2,6-dimethylaniline) M3403 5G $94
4,4'-Methylenebis(2,6-dimethylaniline) M3403 25G $282
4,4'-Methylenebis(2,6-dimethylaniline) FM147042 0.1kg $220.66
4,4'-Methylenebis(2,6-dimethylaniline) FM147042 0.25kg $454.3
More product size

4,4'-Methylenebis(2,6-dimethylaniline) Properties

Melting point 121-123 °C(lit.)
Boiling point 424.9±40.0 °C(Predicted)
Density 1.066±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 20℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 5.05±0.25(Predicted)
Water Solubility 27.02mg/L at 20℃
InChI 1S/C17H22N2/c1-10-5-14(6-11(2)16(10)18)9-15-7-12(3)17(19)13(4)8-15/h5-8H,9,18-19H2,1-4H3
InChIKey OMHOXRVODFQGCA-UHFFFAOYSA-N
SMILES Cc1cc(Cc2cc(C)c(N)c(C)c2)cc(C)c1N
LogP 2.6 at 25℃
CAS DataBase Reference 4073-98-7(CAS DataBase Reference)
FDA UNII KZX9T33K7F
Proposition 65 List 4,4'-Methylene bis(2-chloroaniline)
Proposition 65 List 4,4'-Methylene bis(2-methylaniline)
UNSPSC Code 12162002
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  6.1
HS Code  29029090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
0
2 0

4,4'-Methylenebis(2,6-dimethylaniline) price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 360791 4,4′-Methylenebis(2,6-dimethylaniline) 99% 4073-98-7 5g $50.7 2026-04-30 Buy
TCI Chemical M3403 4,4'-Methylenebis(2,6-dimethylaniline) 4073-98-7 5G $94 2026-04-30 Buy
TCI Chemical M3403 4,4'-Methylenebis(2,6-dimethylaniline) 4073-98-7 25G $282 2026-04-30 Buy
Biosynth FM147042 4,4'-Methylenebis(2,6-dimethylaniline) 4073-98-7 0.1kg $220.66 2026-06-04 Buy
Biosynth FM147042 4,4'-Methylenebis(2,6-dimethylaniline) 4073-98-7 0.25kg $454.3 2026-06-04 Buy
Product number Packaging Price Buy
360791 5g $50.7 Buy
M3403 5G $94 Buy
M3403 25G $282 Buy
FM147042 0.1kg $220.66 Buy
FM147042 0.25kg $454.3 Buy

4,4'-Methylenebis(2,6-dimethylaniline) Chemical Properties,Uses,Production

Chemical Properties

Off-white powder

Flammability and Explosibility

Not classified

Synthesis

Formaldehyde

50-00-0

2,6-Dimethylaniline

87-62-7

4,4'-Methylenebis(2,6-dimethylaniline)

4073-98-7

To a mixed solution of 2,6-dimethylaniline (10.00 g, 0.083 mol) and formaldehyde (4.03 g, 0.054 mol, 0.65 equiv) was slowly added dilute hydrochloric acid (2.2 ml, 0.1 M). The reaction mixture was stirred at 70 °C overnight. After completion of the reaction, the dark red solution was cooled to room temperature and diluted with dichloromethane (15 ml). Subsequently, a minimum amount of concentrated hydrochloric acid (2 ml) was added dropwise to the solution and stirring was continued for 2 h at room temperature followed by filtration. The resulting white salt was washed well with dichloromethane and dried in air. The dried salt was suspended in ether (70 ml), saturated aqueous sodium hydroxide solution was added and stirred until the solid was completely dissolved. The aqueous phase was extracted with ether (2 x 70 ml), the organic phases were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure to afford the target product 4-(4-amino-3,5-dimethylbenzyl)-2,6-dimethylaniline (2a) as an orange solid (8.97 g, 86% yield).

References

[1] Russian Journal of Organic Chemistry, 2009, vol. 45, # 4, p. 528 - 535
[2] Patent: WO2005/118605, 2005, A1. Location in patent: Page/Page column 107
[3] Bulletin des Societes Chimiques Belges, 1989, vol. 98, # 5, p. 319 - 326
[4] Monatshefte fuer Chemie, 1898, vol. 19, p. 641
[5] Journal of Materials Chemistry, 1999, vol. 9, # 7, p. 1425 - 1429

4,4'-Methylenebis(2,6-dimethylaniline) Preparation Products And Raw materials

Global( 128)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 17389186172 1077@dideu.com China 3999 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29626 60
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2949 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 951 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Fuxin Pharmaceutical
+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
Shanghai Daeyeon Chemicals Co., Ltd
021-64478606 15900664856 daeyeon001@vip.163.com China 2062 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58

View Lastest Price from 4,4'-Methylenebis(2,6-dimethylaniline) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4,4'-Methylenebis(2,6-dimethylaniline) pictures 2026-08-07 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
$20.00-30.00 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
4,4'-Methylenebis(2,6-dimethylaniline) pictures 2020-01-13 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
$1.00 1g 98% 100KG Career Henan Chemical Co
3,3'5,5'-TETRAMETHYL-4,4'-DIAMINODIPHENYLMETHANE 4-(4-AMINO-3,5-DIMETHYLBENZYL)-2,6-DIMETHYLANILINE 4,4'-METHYLENEDI-2,6-XYLIDINE LABOTEST-BB LT00160072 AURORA KA-6230 4,4''-METHYLENEBIS(2,6-DIMETHYLANILINE) (KG LEVEL) 4,4'-Methylenebis(2,6-dimethylaniline) ,99% 4,4'-Methylenebis(2,6-dimethylbenzenamine) [4-(4-amino-3,5-dimethyl-benzyl)-2,6-dimethyl-phenyl]amine 4-[(4-amino-3,5-dimethylphenyl)methyl]-2,6-dimethylaniline 4-[(4-azanyl-3,5-dimethyl-phenyl)methyl]-2,6-dimethyl-aniline 4-(4-Amino-3,5-dimethylbenzyl) BenzenaMine,4,4'-Methylenebis[2,6-diMethyl- 4-[(4-aminophenyl)methyl]-2,6-dimethylaniline enebis(2,6-dimethyL 4,4-Methylenebis (2,6-dimethylaniline) (Stellar-2017) 4,4'-Methylenebis(2,6-dimethylaniline) 4,4'-Methylenebis(2,6-dimethylaniline) 4,4'-methylenebis(2,6-xylidine) 4,4'-Methylenebis 4073-98-7 C17H22N2 CH2C6H2CH32NH22 Industrial/Fine Chemicals Amines Miscellaneous Amine Monomers Monomers Primary Amines