4,4'-Methylenebis(2,6-dimethylaniline)
- CAS No.
- 4073-98-7
- Chemical Name:
- 4,4'-Methylenebis(2,6-dimethylaniline)
- Synonyms
- 4,4'-Methylenebis;4,4'-methylenebis(2,6-xylidine);AURORA KA-6230;enebis(2,6-dimethyL;LABOTEST-BB LT00160072;4,4'-METHYLENEDI-2,6-XYLIDINE;4-(4-Amino-3,5-dimethylbenzyl);4,4'-Methylenebis(2,6-dimethylaniline);4,4'-Methylenebis(2,6-dimethylaniline);4,4'-Methylenebis(2,6-dimethylbenzenamine)
- CBNumber:
- CB5273555
- Molecular Formula:
- C17H22N2
- Molecular Weight:
- 254.37
- MDL Number:
- MFCD00058680
- MOL File:
- 4073-98-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4,4′-Methylenebis(2,6-dimethylaniline) 99% | 360791 | 5g | $50.7 |
| 4,4'-Methylenebis(2,6-dimethylaniline) | M3403 | 5G | $94 |
| 4,4'-Methylenebis(2,6-dimethylaniline) | M3403 | 25G | $282 |
| 4,4'-Methylenebis(2,6-dimethylaniline) | FM147042 | 0.1kg | $220.66 |
| 4,4'-Methylenebis(2,6-dimethylaniline) | FM147042 | 0.25kg | $454.3 |
| More product size | |||
| Melting point | 121-123 °C(lit.) |
|---|---|
| Boiling point | 424.9±40.0 °C(Predicted) |
| Density | 1.066±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 5.05±0.25(Predicted) |
| Water Solubility | 27.02mg/L at 20℃ |
| InChI | 1S/C17H22N2/c1-10-5-14(6-11(2)16(10)18)9-15-7-12(3)17(19)13(4)8-15/h5-8H,9,18-19H2,1-4H3 |
| InChIKey | OMHOXRVODFQGCA-UHFFFAOYSA-N |
| SMILES | Cc1cc(Cc2cc(C)c(N)c(C)c2)cc(C)c1N |
| LogP | 2.6 at 25℃ |
| CAS DataBase Reference | 4073-98-7(CAS DataBase Reference) |
| FDA UNII | KZX9T33K7F |
| Proposition 65 List | 4,4'-Methylene bis(2-chloroaniline) |
| Proposition 65 List | 4,4'-Methylene bis(2-methylaniline) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29029090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4,4'-Methylenebis(2,6-dimethylaniline) price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 360791 | 4,4′-Methylenebis(2,6-dimethylaniline) 99% | 4073-98-7 | 5g | $50.7 | 2026-04-30 | Buy |
| TCI Chemical | M3403 | 4,4'-Methylenebis(2,6-dimethylaniline) | 4073-98-7 | 5G | $94 | 2026-04-30 | Buy |
| TCI Chemical | M3403 | 4,4'-Methylenebis(2,6-dimethylaniline) | 4073-98-7 | 25G | $282 | 2026-04-30 | Buy |
| Biosynth | FM147042 | 4,4'-Methylenebis(2,6-dimethylaniline) | 4073-98-7 | 0.1kg | $220.66 | 2026-06-04 | Buy |
| Biosynth | FM147042 | 4,4'-Methylenebis(2,6-dimethylaniline) | 4073-98-7 | 0.25kg | $454.3 | 2026-06-04 | Buy |
4,4'-Methylenebis(2,6-dimethylaniline) Chemical Properties,Uses,Production
Chemical Properties
Off-white powder
Flammability and Explosibility
Not classified
Synthesis
50-00-0
87-62-7
4073-98-7
To a mixed solution of 2,6-dimethylaniline (10.00 g, 0.083 mol) and formaldehyde (4.03 g, 0.054 mol, 0.65 equiv) was slowly added dilute hydrochloric acid (2.2 ml, 0.1 M). The reaction mixture was stirred at 70 °C overnight. After completion of the reaction, the dark red solution was cooled to room temperature and diluted with dichloromethane (15 ml). Subsequently, a minimum amount of concentrated hydrochloric acid (2 ml) was added dropwise to the solution and stirring was continued for 2 h at room temperature followed by filtration. The resulting white salt was washed well with dichloromethane and dried in air. The dried salt was suspended in ether (70 ml), saturated aqueous sodium hydroxide solution was added and stirred until the solid was completely dissolved. The aqueous phase was extracted with ether (2 x 70 ml), the organic phases were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure to afford the target product 4-(4-amino-3,5-dimethylbenzyl)-2,6-dimethylaniline (2a) as an orange solid (8.97 g, 86% yield).
References
[1] Russian Journal of Organic Chemistry, 2009, vol. 45, # 4, p. 528 - 535
[2] Patent: WO2005/118605, 2005, A1. Location in patent: Page/Page column 107
[3] Bulletin des Societes Chimiques Belges, 1989, vol. 98, # 5, p. 319 - 326
[4] Monatshefte fuer Chemie, 1898, vol. 19, p. 641
[5] Journal of Materials Chemistry, 1999, vol. 9, # 7, p. 1425 - 1429
4,4'-Methylenebis(2,6-dimethylaniline) Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3999 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 951 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Shanghai Daeyeon Chemicals Co., Ltd | 021-64478606 15900664856 | daeyeon001@vip.163.com | China | 2062 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
View Lastest Price from 4,4'-Methylenebis(2,6-dimethylaniline) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-07 | 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
|
$20.00-30.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2020-01-13 | 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
|
$1.00 | 1g | 98% | 100KG | Career Henan Chemical Co |
-

- 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
- $20.00-30.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- 4,4'-Methylenebis(2,6-dimethylaniline)
4073-98-7
- $1.00
- 98%
- Career Henan Chemical Co
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