Azodicarboxylic bismorpholide
- CAS No.
- 10465-82-4
- Chemical Name:
- Azodicarboxylic bismorpholide
- Synonyms
- AZODICARBOXYLIC DIMORPHOLIDE;Diazene-1,2-diylbis(morpholinomethanone);NSC 356022;Azodicarboxylic bismorpholide;4,4'-Azodicarbonylbis(morpholine);Azodicarboxylic dimorpholide >=98.0% (N);Methanone,1,1'-(1,2-diazenediyl)bis[1-(4-morpholinyl)-;Methanone,1,1'-(1,2-diazenediyl)bis[1-(4-morpholinyl)-
- CBNumber:
- CB5454231
- Molecular Formula:
- C10H16N4O4
- Molecular Weight:
- 256.26
- MDL Number:
- MFCD00043006
- MOL File:
- 10465-82-4.mol
- MSDS File:
- SDS
| Melting point | 141-143 °C |
|---|---|
| Boiling point | 397.6±52.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | -0.97±0.20(Predicted) |
| Appearance | Light yellow to yellow Solid |
| BRN | 1013753 |
| InChI | InChI=1S/C10H16N4O4/c15-9(13-1-5-17-6-2-13)11-12-10(16)14-3-7-18-8-4-14/h1-8H2 |
| InChIKey | CHAMTJKQPOMXTI-UHFFFAOYSA-N |
| SMILES | N(C(N1CCOCC1)=O)=NC(N1CCOCC1)=O |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302+H312+H332-H315-H319-H228 |
| Precautionary statements | P261-P210-P264-P280-P370+P378-P302+P352+P312 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| REACH Registrations | Inactive |
Azodicarboxylic bismorpholide price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 11628 | Azodicarboxylic dimorpholide ≥98.0% (N) | 10465-82-4 | 5g | $369 | 2026-04-30 | Buy |
| Matrix Scientific | 100010 | Diazene-1,2-diylbis(morpholinomethanone) | 10465-82-4 | 1.00g | $284 | 2026-05-18 | Buy |
| Matrix Scientific | 100010 | Diazene-1,2-diylbis(morpholinomethanone) | 10465-82-4 | 5.00g | $840 | 2026-05-18 | Buy |
| Synthonix | D53203 | Diazene-1,2-diylbis(morpholinomethanone) 97% | 10465-82-4 | 1g | $56.96 | 2026-05-06 | Buy |
| Synthonix | D53203 | Diazene-1,2-diylbis(morpholinomethanone) 97% | 10465-82-4 | 5g | $80 | 2026-05-06 | Buy |
Azodicarboxylic bismorpholide Chemical Properties, Uses, Production
Uses
Azodicarboxylic dimorpholide has been used in the galanthamine ring system reaction that utilizes an intramolecular Heck reaction to establish the benzofuran ring system. Galanthamine exhibits potent acetylcholinesterase inhibitory activity and is important in the management of Alzheimer′s disease.
General Description
Azodicarboxylic dimorpholide is a yellow to dark yellow powder or crystals
Synthesis
110-91-8
1972-28-7
10465-82-4
To a stirred mixture of diethyl azodicarboxylate (40 wt% toluene solution, 5 mL, 11.5 mmol, 1 eq.) and ether (25 mL) was slowly added an ether solution (25 mL) of morpholine (1.98 mL, 23 mmol, 2 eq.) through a dropping funnel at 0 °C, the dropwise addition process continued for 3 hours. The reaction mixture was then continued to stir for 2 hours under slow warming to room temperature. The resulting yellow precipitate was collected by vacuum filtration, washed with cold ether and dried over a filter to afford azodicarbonyl dimorpholine (ADDM) as a yellow-orange solid (1.62 g, 55% yield). The NMR hydrogen spectrum (CDCl3, 400 MHz) data were as follows: δ 3.61 (multiple peaks, 4H, 2 × CH2), 3.74 (multiple peaks, 8H, 4 × CH2), 3.83 (multiple peaks, 4H, 2 × CH2).
References
[1] Tetrahedron Letters, 2013, vol. 54, # 35, p. 4624 - 4628
Azodicarboxylic bismorpholide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SuZhou Jonathan New Material Technology Co., Ltd. | 0512-68312916,63926215 18912725070;18013709950 | jon@jonnmt.com | China | 109 | 58 |
| Huzhou Huanyu Biotechnology Co. , Ltd. | 18757211187 18994340517 | 709951195@qq.com | China | 94 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Suzhou BEC Biological Technology Co., Ltd | +86-512-68095917 17712685869 | sales@bek.com.cn | China | 142 | 59 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Letopharm Limited | +86-21-5821 5861 | sales@letopharm.com | China | 70 | 55 |
View Latest Price from Azodicarboxylic bismorpholide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | AZODICARBOXYLIC BISMORPHOLIDE
10465-82-4
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
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- AZODICARBOXYLIC BISMORPHOLIDE
10465-82-4
- $1.00
- 99%
- Career Henan Chemical Co
