ChemicalBook >> CAS DataBase List >>2',3',4'-Trimethoxyacetophenone

2',3',4'-Trimethoxyacetophenone

2',3',4'-Trimethoxyacetophenone structure

CAS No.: 13909-73-4

Chemical Name:: 2',3',4'-Trimethoxyacetophenone

Synonyms: 1-(2,3,4-Trimethoxyphenyl)ethanone;TIMTEC-BB SBB008574;2-3-4-trimethxoyacetophenone;2,3,4-TRIMETHOXYACETOPHENONE;2,3,4-Tromethoxyacetophenone;2',3',4'-Trimethoxyacetophenone;222′,3′,4′-Trimethoxyacetophenone;2',3',4'-Trimethoxyacetophenone97%;2'',3'',4''-Trimethoxyacetophenone;2',3',4'-Trimethoxyacetophenone,96%

CBNumber:: CB5454387

Molecular Formula:: C11H14O4

Molecular Weight:: 210.23

MDL Number:: MFCD00008726

MOL File:: 13909-73-4.mol

MSDS File:: SDS

Last updated:2026-09-12 18:53:33

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2',3',4'-Trimethoxyacetophenone Properties

Melting point	14-15 °C(lit.)
Boiling point	295-297 °C(lit.)
Density	1.155 g/mL at 25 °C(lit.)
refractive index	n20/D 1.5384(lit.)
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
color	Colorless to Light yellow to Light orange
InChI	1S/C11H14O4/c1-7(12)8-5-6-9(13-2)11(15-4)10(8)14-3/h5-6H,1-4H3
InChIKey	PKNAATJMQOUREZ-UHFFFAOYSA-N
SMILES	COc1ccc(C(C)=O)c(OC)c1OC
LogP	1.630
CAS DataBase Reference	13909-73-4(CAS DataBase Reference)
FDA UNII	F3JC7ZP11A
EPA Substance Registry System	2',3',4'-Trimethoxyacetophenone (13909-73-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves

Hazard Codes

Safety Statements

24/25

WGK Germany

RTECS

AN0531000

Hazard Note

Irritant

HS Code

29145000

Storage Class

10 - Combustible liquids

NFPA 704

	1
0		0

2',3',4'-Trimethoxyacetophenone price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	189812	2′,3′,4′-Trimethoxyacetophenone 96%	13909-73-4	5g	$132	2023-06-20	Buy
TCI Chemical	T1517	2',3',4'-Trimethoxyacetophenone >97.0%(GC)	13909-73-4	5g	$68	2026-04-30	Buy
ChemScene	CS-M2300	2',3',4'-Trimethoxyacetophenone ≥98%	13909-73-4	10g	$55	2026-06-04	Buy
ChemScene	CS-M2300	2',3',4'-Trimethoxyacetophenone ≥98%	13909-73-4	25g	$130	2026-06-04	Buy
Apolloscientific	OR4705	2',3',4'-Trimethoxyacetophenone 98%	13909-73-4	5g	$52	2026-06-04	Buy

Product number	Packaging	Price	Buy
189812	5g	$132	Buy
T1517	5g	$68	Buy
CS-M2300	10g	$55	Buy
CS-M2300	25g	$130	Buy
OR4705	5g	$52	Buy

2',3',4'-Trimethoxyacetophenone Chemical Properties, Uses, Production

Chemical Properties

clear yellow liquid

Uses

2',3',4'-Trimethoxyacetophenone is an organic compound with a benzene ring and an acetyl group. 2',3',4'-Trimethoxyacetophenone can be used as a raw material for synthesizing dyes, fragrances, and certain pesticides[1].

Preparation

Obtained by reaction of dimethyl sulfate with gallacetophenone in methanol in the presence of potassium hydroxide.

General Description

2′,3′,4′-Trimethoxyacetophenone on reaction with BCl₃gives the corresponding 2,3-dihydroxy-4-methoxy compounds.

Synthesis

528-21-2

77-78-1

13909-73-4

To a solution of 2',3',4'-trihydroxyacetophenone (1.66 g, 10 mmol) in acetone (50 mL) was added potassium carbonate (11 g) and dimethyl sulfate (6 mL, 30 mmol). The reaction was stirred at 45 °C for 17 h. The reaction was terminated by the addition of water. The reaction mixture was filtered, neutralized with 1 M HCl and then extracted with dichloromethane (200 mL). The organic layer was washed with brine (150 mL) and the crude product was purified by silica gel column chromatography (petroleum ether/ethyl acetate, 5:1). Yield: 1.85 g (88%).1H NMR (CDCl3, 300 MHz) δ 7.50 (d, J = 8.8 Hz, 1H), 6.68 (d, J = 8.8 Hz, 1H), 3.94 (s, 3H), 3.89 (s, 3H), 3.85 (s, 3H), 2.58 (s, 3H) ppm.13C NMR ( CDCl3, 75 MHz) δ 198.01, 157.44, 154.30, 128.99, 125.78, 125.57, 106.99, 61.30, 60.80, 56.06, 30.97 ppm. Pharm. Bull. 1984, 32, 3354-3360.

References

[1] Lenz G R, et al. Synthesis of the novel isoquinoline enamide alkaloid polycarpine[J]. Journal of Heterocyclic Chemistry, 1981, 18(4): 691-693.

2',3',4'-Trimethoxyacetophenone Preparation Products And Raw materials

Raw materials

2',3',4'-Trihydroxyacetophenone Dimethyl sulfate Potassium carbonate Water

Preparation Products

2,3,4-Trimethoxyphenylacetic acid 2'-Hydroxy-3',4'-dimethoxyacetophenone

2',3',4'-Trimethoxyacetophenone Suppliers

Global Suppliers ( 136)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Harvest Chemical Industrial Co., Ltd.	15721252604 17321035817	sales@harvest-chem.com	China	2829	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Shanghai Ennopharm Co., Ltd.	+86 (21) 6435-5022		China	4263	65
Sinopharm Chemical Reagent Co,Ltd.	86-21-63210123	sj_scrc@sinopharm.com	China	9791	79

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Harvest Chemical Industrial Co., Ltd.	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Shanghai Ennopharm Co., Ltd.	65
Sinopharm Chemical Reagent Co,Ltd.	79

View Latest Price from 2',3',4'-Trimethoxyacetophenone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	2',3',4'-Trimethoxyacetophenone 13909-73-4			98%	10g	TargetMol Chemicals Inc.
	2019-07-12	2',3',4'-TRIMETHOXYACETOPHENONE 13909-73-4	$1.00	1KG	99%	100kg	Career Henan Chemical Co

2',3',4'-Trimethoxyacetophenone
13909-73-4
$0.00
98%
TargetMol Chemicals Inc.

2',3',4'-TRIMETHOXYACETOPHENONE
13909-73-4
$1.00
99%
Career Henan Chemical Co

2',3',4'-Trimethoxyacetophenone Spectrum

2',3',4'-TRIMETHOXYACETOPHENONE(13909-73-4)MS 2',3',4'-TRIMETHOXYACETOPHENONE(13909-73-4)¹HNMR 2',3',4'-TRIMETHOXYACETOPHENONE(13909-73-4)¹³CNMR 2',3',4'-TRIMETHOXYACETOPHENONE(13909-73-4)IR1 2',3',4'-TRIMETHOXYACETOPHENONE(13909-73-4)Raman

13909-73-4 (2',3',4'-Trimethoxyacetophenone) Related Search:

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2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-4-quinolinamine 1-(2,3,4-Trimethoxyphenyl)ethanone Ethanone, 1-(2,3,4-trimethoxyphenyl)- TIMTEC-BB SBB008574 2,3,4-TRIMETHOXYACETOPHENONE 2-3-4-trimethxoyacetophenone 2',3',4'-Trimethoxyacetophenone 2,3,4-Tromethoxyacetophenone 2',3',4'-Trimethoxyacetophenone 97% 2,3,4-Tromethoxyacetophenone 2′,3′,4′-Trimethoxyacetophenone, GC 97% 2',3',4'-Trimethoxyacetophenone,96% 1-(2,3,4-Trimethoxyphenyl)ethan-1-one 2-propyloxy-4,6-Diacetyl-N-ethylaniline Methyl 2,3,4-triMethoxyphenyl ketone 2',3',4'-Trimethoxyacetophenone97% 2',3',4'-Trimethoxyacetophenone 2'',3'',4''-Trimethoxyacetophenone 2′,3′,4′-Trimethoxyacetophenone, CAS 13909-73-4 222′,3′,4′-Trimethoxyacetophenone 13909-73-4 Building Blocks C11 to C12 Carbonyl Compounds Ketones Organic Building Blocks Building Blocks C11 to C12 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Aromatic Acetophenones & Derivatives (substituted) C11 to C12 Carbonyl Compounds Ketones