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2'-Hydroxy-3',4'-dimethoxyacetophenone

2'-Hydroxy-3',4'-dimethoxyacetophenone structure

CAS No.: 5396-18-9

Chemical Name:: 2'-Hydroxy-3',4'-dimethoxyacetophenone

Synonyms: AKOS 212-80;3,4-Methoxy-2-Hydroxyacetophenone;3,4-DIMETHOXY-2-HYDROXYACETOPHENONE;GALLACETOPHENONE-3,4-DIMETHYL ETHER;2-HYDROXY-3,4-DIMETHOXYACETOPHENONE;2-HYDROXY-3,4'-DIMETHOXYACETOPHENONE;GALLACETOPHENONE 3',4'-DIMETHYL ETHER;Gallacetophenone 3’，4’-Dimethyl Ether;3',4'-Dimethoxy-2'-hydroxyacetophenone;2'-Hydroxy-3',4'-dimethoxyacetophenone

CBNumber:: CB2457741

Molecular Formula:: C10H12O4

Molecular Weight:: 196.2

MDL Number:: MFCD00016684

MOL File:: 5396-18-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:51:18

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2'-Hydroxy-3',4'-dimethoxyacetophenone Properties

Melting point	75-77°C
Boiling point	308.1±37.0 °C(Predicted)
Density	1.172±0.06 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Chloroform, Methanol
form	powder
pka	9.79±0.15(Predicted)
color	Off-White
InChI	InChI=1S/C10H12O4/c1-6(11)7-4-5-8(13-2)10(14-3)9(7)12/h4-5,12H,1-3H3
InChIKey	BCEPNLMYVYJIHU-UHFFFAOYSA-N
SMILES	C(=O)(C1=CC=C(OC)C(OC)=C1O)C
CAS DataBase Reference	5396-18-9(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE	Eyeshields, Gloves, type N95 (US)
Hazard Codes	Xi
WGK Germany	3
HS Code	29145090
Storage Class	11 - Combustible Solids

2'-Hydroxy-3',4'-dimethoxyacetophenone price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	G1411	Gallacetophenone 3′,4′-dimethyl ether	5396-18-9	1g	$78	2023-06-20	Buy
TCI Chemical	H1205	2'-Hydroxy-3',4'-dimethoxyacetophenone >98.0%(GC)	5396-18-9	5g	$46	2026-04-30	Buy
TCI Chemical	H1205	2'-Hydroxy-3',4'-dimethoxyacetophenone >98.0%(GC)	5396-18-9	25g	$226	2026-04-30	Buy
TRC	TRC-G190500-25G	Gallacetophenone 3’,4’-Dimethyl Ether	5396-18-9	25g	$730	2026-06-03	Buy
TRC	TRC-G190500-2.5G	Gallacetophenone 3’,4’-Dimethyl Ether	5396-18-9	2.5g	$108	2026-06-03	Buy

Product number	Packaging	Price	Buy
G1411	1g	$78	Buy
H1205	5g	$46	Buy
H1205	25g	$226	Buy
TRC-G190500-25G	25g	$730	Buy
TRC-G190500-2.5G	2.5g	$108	Buy

2'-Hydroxy-3',4'-dimethoxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Gallacetophenone 3’,4’-Dimethyl ether is a phenolic compound with potential 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity.

Preparation

Preparation by reaction of acetyl chloride on pyrogallol trimethyl ether,with aluminium chloride in carbon disulfide, in boiling ethyl ether (77%) or in benzene at 45–50° (77%) with mercuric chloride without solvent at 100° (40%).

2'-Hydroxy-3',4'-dimethoxyacetophenone synthesis

Synthesis of 2'-Hydroxy-3',4'-dimethoxyacetophenone from 2,3-Dimethoxyphenol

2'-Hydroxy-3',4'-dimethoxyacetophenone Preparation Products And Raw materials

Raw materials

2,3-Dimethoxyphenol acetate 2',3',4'-Trimethoxyacetophenone 2',3',4'-Trihydroxyacetophenone 3,4-Dimethoxyacetophenone 2,3-Dimethoxyphenol

Pyrogallol Acetyl chloride Dimethyl sulfate Iodomethane 1,2,3-Trimethoxybenzene

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Preparation Products

7,8-Dihydroxyflavone

2'-Hydroxy-3',4'-dimethoxyacetophenone Suppliers

Global( 101)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd	0512-66317708 13372112871	huijuan@zitrans.cn	China	2260	58
Yichang Xinnada Biotechnology Co., Ltd	15872392564 15872392564	sunwei@xndswkj.cn	China	20	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9643	60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80

Supplier	Advantage
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd	58
Yichang Xinnada Biotechnology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Chemsky（shanghai）International Co.,Ltd.	50
Spectrum Chemical Manufacturing Corp.	60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	80

View Lastest Price from 2'-Hydroxy-3',4'-dimethoxyacetophenone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-13	2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE 5396-18-9		1KG	99%	2000	Shenzhen Nexcon Pharmatechs Ltd.

2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE
5396-18-9
99%
Shenzhen Nexcon Pharmatechs Ltd.

2'-Hydroxy-3',4'-dimethoxyacetophenone Spectrum

2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE(5396-18-9)FT-IR

5396-18-9(2'-Hydroxy-3',4'-dimethoxyacetophenone)Related Search:

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GALLACETOPHENONE 3',4'-DIMETHYL ETHER GALLACETOPHENONE-3,4-DIMETHYL ETHER AKOS 212-80 3,4-DIMETHOXY-2-HYDROXYACETOPHENONE 2-HYDROXY-3,4'-DIMETHOXYACETOPHENONE 2-HYDROXY-3,4-DIMETHOXYACETOPHENONE 1-(2-hydroxy-3,4-dimethoxyphenyl)ethanone 1-(2-hydroxy-3,4-dimethoxy-phenyl)ethanone 6-Acetyl-2,3-dimethoxyphenol, 4-Acetyl-3-hydroxyveratrole, Gallacetophenone 3',4'-dimethyl ether 6-Acetyl-2,3-dimethoxyphenol, Gallacetophenone 3',4'-dimethyl ether, 1-(3,4-Dimethoxy-2-hydroxyphenyl)ethan-1-one 2'-Hydroxy-3',4'-dimethoxyacetophenone> Ethanone, 1-(2-hydroxy-3,4-dimethoxyphenyl)- 3',4'-Dimethoxy-2'-hydroxyacetophenone Gallacetophenone 3’，4’-Dimethyl Ether Gallacetophenone 3′,4′-dimethyl ether, CAS 5396-18-9 3,4-Methoxy-2-Hydroxyacetophenone 2'-Hydroxy-3',4'-dimethoxyacetophenone 5396-18-9 Building Blocks C10 Carbonyl Compounds Organic Building Blocks Ketones Aromatics Intermediates Miscellaneous Reagents Aromatic Acetophenones & Derivatives (substituted) Building block pharmaceutical fine chemicals