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2-Chloro-5-nitroanisole

2-Chloro-5-nitroanisole Structure
2-Chloro-5-nitroanisole structure
CAS No.
1009-36-5
Chemical Name:
2-Chloro-5-nitroanisole
Synonyms
2-METHOXY-4-NITROCHLOROBENZENE;1-Chloro-2-methoxy-4-nitrobenzene;2-METHOXY-4-NIT;2-Chloro-5-nitropheno;2-Chloro-5-nitroanisole;2-Chloro-5-nitroanisole >2-chloro-5-nitrobenzyl ether;4-Chloro-3-methoxynitrobenzene;1-chloro-2-methoxy-4-nitro-benzen;2-Chloro-5-nitrophenyl methyl ether
CBNumber:
CB5469406
Molecular Formula:
C7H6ClNO3
Molecular Weight:
187.58
MDL Number:
MFCD00079739
MOL File:
1009-36-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:33
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2-Chloro-5-nitroanisole Properties

Melting point 81-83°C
Boiling point 287.3±20.0 °C(Predicted)
Density 1.366±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Solid
color Brown
CAS DataBase Reference 1009-36-5(CAS DataBase Reference)
EPA Substance Registry System 2-Chloro-5-nitroanisole (1009-36-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,N,Xn
Risk Statements  36/37/38-51-22-36/38
Safety Statements  26-36/37/39-28
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29093090

2-Chloro-5-nitroanisole price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1773 2-Chloro-5-nitroanisole min. 98.0 % 1009-36-5 5G $29 2026-04-30 Buy
TCI Chemical C1773 2-Chloro-5-nitroanisole min. 98.0 % 1009-36-5 25G $86 2026-04-30 Buy
TRC TRC-C373775-5G 2-Chloro-5-nitroanisole 1009-36-5 5g $249 2026-06-03 Buy
TRC TRC-C373775-2G 2-Chloro-5-nitroanisole 1009-36-5 2g $123 2026-06-03 Buy
TRC TRC-C373775-1G 2-Chloro-5-nitroanisole 1009-36-5 1g $65 2026-06-03 Buy
Product number Packaging Price Buy
C1773 5G $29 Buy
C1773 25G $86 Buy
TRC-C373775-5G 5g $249 Buy
TRC-C373775-2G 2g $123 Buy
TRC-C373775-1G 1g $65 Buy

2-Chloro-5-nitroanisole Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

2-Chloro-5-nitroanisole (cas# 1009-36-5) is a compound useful in organic synthesis.

Synthesis

2-Methoxy-4-nitroaniline

97-52-9

2-CHLORO-5-NITROANISOLE

1009-36-5

General procedure for the synthesis of 2-chloro-5-nitroanisole from 2-methoxy-4-nitroaniline: In an agate mortar, camphorsulfonic acid (1.5 mmol), tert-butyl nitrite (3.0 mmol), benzyltriethylammonium chloride (2.5 mmol), and a catalytic amount of copper(II) chloride (1 mol%) were mixed with 2-methoxy-4-nitroaniline (1.25 mmol) were mixed. The mixture was vigorously ground for 15-20 min until nitrogen release stopped completely. Upon completion of the reaction (confirmed by thin layer chromatography), the crude product was treated according to the treatment of aryl bromide reaction and purified by column chromatography using hexane/dichloromethane as eluting solvent. The physical properties and 1H NMR data of the resulting product were consistent with those of commercially available analytically pure samples.

References

[1] Tetrahedron, 2013, vol. 69, # 16, p. 3511 - 3517
[2] Environmental Toxicology and Chemistry, 2001, vol. 20, # 7, p. 1381 - 1389
[3] Tetrahedron Letters, 2010, vol. 51, # 51, p. 6769 - 6771
[4] Tetrahedron, 2010, vol. 66, # 37, p. 7418 - 7422
[5] Chemische Berichte, 1899, vol. 32, p. 2623

2-Chloro-5-nitroanisole Preparation Products And Raw materials

Raw materials

2-Chloro-5-nitrophenol 2-Methoxy-4-nitroaniline tert-Butyl nitrite Benzyltriethylammonium chloride (1S)-(+)-Camphor-10-sulphonic acid
Copper(II) chloride

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Preparation Products

2-Chloro-5-nitrophenol 5-Chloro-2-nitroanisole 2-Chloro-5-aminophenol N-[4-Chloro-3-(triisopropylsilyloxy)phenyl]-2,2-dimethylpropanamide

2-Chloro-5-nitroanisole Suppliers

Global Suppliers ( 203)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50

View Latest Price from 2-Chloro-5-nitroanisole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-5-NITROANISOLE pictures 2026-09-02 2-CHLORO-5-NITROANISOLE
1009-36-5
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Chloro-5-nitroanisole pictures 2020-02-26 2-Chloro-5-nitroanisole
1009-36-5
 1KG 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
2-CHLORO-5-NITROANISOLE pictures 2019-07-06 2-CHLORO-5-NITROANISOLE
1009-36-5
 $2.00 1kg 99% 100kg Career Henan Chemical Co

2-Chloro-5-nitroanisole Spectrum

2-CHLORO-5-NITROANISOLE(1009-36-5)1HNMR

1009-36-5 (2-Chloro-5-nitroanisole) Related Search:

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5-(2-Chloro-5-nitro-phenoxymethyl)-furan-2-carboxylic acid methyl ester Benzyl 2,4-dichloro-5-nitrophenyl ether 5-Chloro-2-methoxy-4-nitroaniline

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4-Chloro-3-methoxynitrobenzene, 1-Chloro-2-methoxy-4-nitrobenzene, 2-Chloro-5-nitrophenyl methyl ether 1-Chloro-2-Methoxy-4-nitrobenzene, 98.0%(GC) 4-Chloro-3-methoxynitrobenzene 2-METHOXY-4-NIT 1-chloro-2-methoxy-4-nitro-benzen 2-Chloro-5-nitroanisole > Benzene, 1-chloro-2-methoxy-4-nitro- 2-CHLORO-5-NITROANISOLE ISO 9001：2015 REACH 2-Chloro-5-nitropheno 2-Chloro-5-nitrophenyl methyl ether 2-chloro-5-nitrobenzyl ether 1-Chloro-2-methoxy-4-nitrobenzene 2-METHOXY-4-NITROCHLOROBENZENE 2-Chloro-5-nitroanisole 1009-36-5 C7H6ClNO3 Building Blocks Chemical Synthesis Aromatics Miscellaneous Reagents New Products for Chemical Synthesis Nitrogen Compounds Organic Building Blocks Anisoles, Alkyloxy Compounds & Phenylacetates Chlorine Compounds Nitro Compounds Anisole