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2-CHLOROPHENETHYLALCOHOL

CAS No.
19819-95-5
Chemical Name:
2-CHLOROPHENETHYLALCOHOL
Synonyms
2-Chlorophenethanol;2-Chlorobenzeneethanol;2-chlorophenethylalchol;2-CHLOROPHENETHYLALCOHOL;2-(O-CHLOROPHENYL)ETHANOL;Benzeneethanol, 2-chloro-;2-(2-Chlorophenyl)ethanol;2-(2-Chlorophenyl)etnanol;o-chlorophenethylic alcohol;2-Chlorophenethylalcohol,98%
CBNumber:
CB5732566
Molecular Formula:
C8H9ClO
Molecular Weight:
156.61
MDL Number:
MFCD00002888
MOL File:
19819-95-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:49
Product description Number Pack Size Price
2-Chlorophenethyl alcohol 98% 193844 5g $99.3
2-(2-Chlorophenyl)ethanol >97.0%(GC) C2169 1g $22
2-(2-Chlorophenyl)ethanol >97.0%(GC) C2169 5g $68
2-(2-Chlorophenyl)ethanol C424280 50g $250
2-(2-Chlorophenyl)ethanol FC64474 25g $250
More product size

2-CHLOROPHENETHYLALCOHOL Properties

Boiling point 84-85 °C/3 mmHg (lit.)
Density 1.19 g/mL at 25 °C (lit.)
refractive index n20/D 1.551(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
pka 14.72±0.10(Predicted)
Specific Gravity 1.19
color Clear colorless
InChI InChI=1S/C8H9ClO/c9-8-4-2-1-3-7(8)5-6-10/h1-4,10H,5-6H2
InChIKey IWNHTCBFRSCBQK-UHFFFAOYSA-N
SMILES C1(CCO)=CC=CC=C1Cl
FDA UNII 3JVZ9G2VBD
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Safety Statements  24/25
WGK Germany  3
HS Code  29052900
NFPA 704
1
0 0

2-CHLOROPHENETHYLALCOHOL price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 193844 2-Chlorophenethyl alcohol 98% 19819-95-5 5g $99.3 2023-06-20 Buy
TCI Chemical C2169 2-(2-Chlorophenyl)ethanol >97.0%(GC) 19819-95-5 1g $22 2025-07-31 Buy
TCI Chemical C2169 2-(2-Chlorophenyl)ethanol >97.0%(GC) 19819-95-5 5g $68 2025-07-31 Buy
TRC C424280 2-(2-Chlorophenyl)ethanol 19819-95-5 50g $250 2021-12-16 Buy
Biosynth Carbosynth FC64474 2-(2-Chlorophenyl)ethanol 19819-95-5 25g $250 2021-12-16 Buy
Product number Packaging Price Buy
193844 5g $99.3 Buy
C2169 1g $22 Buy
C2169 5g $68 Buy
C424280 50g $250 Buy
FC64474 25g $250 Buy

2-CHLOROPHENETHYLALCOHOL Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

2-Chlorophenethyl alcohol may be used in the chemical synthesis of amines.

Definition

ChEBI: 2-Chlorophenethyl alcohol is an organochlorine compound.

Synthesis

2-Chlorophenylacetic acid

2444-36-2

2-CHLOROPHENETHYLALCOHOL

19819-95-5

The general procedure for the synthesis of 2-chlorophenylethanol from o-chlorophenylacetic acid was as follows: first, 20 g of o-chlorophenylacetic acid (o-S1) was dissolved in 200 ml of tetrahydrofuran, stirred and cooled to 0 °C. Subsequently, 8.9 g of lithium aluminum hydride was added in batches and Bi was added as a catalyst. The reaction mixture was warmed up to 25?30°C for the reaction. Upon completion of the reaction, the reaction was terminated by adding 300 ml of water and extracted with 400 ml of dichloromethane. After separation of the organic phase, 20 g of anhydrous sodium sulfate was added for drying. Concentration under reduced pressure at 30-35°C gave 18.3 g of light yellow oil (o-S1-1). Next, phosphorus tribromide was slowly added dropwise to the reaction vial containing o-S1-1 under ice bath conditions, controlling the dropwise temperature at 0-10 °C. After the dropwise addition, stirring was continued for 10 min until white smoke was generated. Subsequently, the reaction mixture was warmed up to 75~80°C and held at this temperature with stirring for 2 hours. Upon completion of the reaction, 30 ml of saturated sodium bicarbonate solution was added to neutralize the reaction and extracted with 200 ml of ethyl acetate. After separation of the organic phase, 20 g of anhydrous sodium sulfate was added for drying. Finally, it was concentrated under reduced pressure at 40?45 °C to give 22.4 g of yellow liquid (neighboring S2) in 87.0% yield.

References

[1] Journal of Medicinal Chemistry, 1981, vol. 24, # 6, p. 678 - 683
[2] Patent: US6342501, 2002, B1. Location in patent: Scheme 2
[3] Angewandte Chemie - International Edition, 2015, vol. 54, # 36, p. 10596 - 10599
[4] Angew. Chem., 2015, vol. 127, p. 10742 - 10745,4
[5] Journal of Organic Chemistry, 1964, vol. 29, p. 3175 - 3179

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View Lastest Price from 2-CHLOROPHENETHYLALCOHOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLOROPHENETHYLALCOHOL pictures 2020-01-10 2-CHLOROPHENETHYLALCOHOL
19819-95-5
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
Pigment Permanent Red F5RK pictures 2020-01-09 Pigment Permanent Red F5RK
1211-16-1
US $1.00 / KG 1KG 99% 1kg-1000kg Career Henan Chemical Co
2-(O-CHLOROPHENYL)ETHANOL 2-CHLOROPHENETHYLALCOHOL o-chlorophenethylic alcohol 2-CHLOROPHENETHYLALCOHOL 98% 2-(2-Chlorophenyl)ethanol Benzeneethanol, 2-chloro- o-Chlorophenylmethylcarbinol 2-(2-Chlorophenyl)etnanol 2-Chlorobenzeneethanol 2-Chlorophenethylalcohol,98% 2-Chlorophenethanol 2-Chlorophenethylalcohol, 98% 25GR 2-(2-Chlorophenyl)ethan-1-ol 2-(2-Chlorophenyl)ethanol > 2-chlorophenethylalchol 19819-95-5 ClC6H4CH2CH2OH Oxygen Compounds Organic Building Blocks Building Blocks Alcohols C7 to C8 Alcohols C7 to C8 Oxygen Compounds Benzhydrols, Benzyl & Special Alcohols