Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-Amino-1-adamantanol

3-Amino-1-adamantanol

3-Amino-1-adamantanol Structure
3-Amino-1-adamantanol structure
CAS No.
702-82-9
Chemical Name:
3-Amino-1-adamantanol
Synonyms
3-AMINO-1-ADAMANTANOL;3-AMINOADAMANTAN-1-OL;4-aminoadamantan-1-ol;3-Amino-1-admantanol;3-Amino-1-hydroxyadamantane;3-Hydroxy-1-aminoadamantane;3-Amino-1-Adamantanamine;1-AMINO-3-HYDROXYADAMANTANE;C1oH17NO;AKOS BB-9784
CBNumber:
CB5777891
Molecular Formula:
C10H17NO
Molecular Weight:
167.25
MDL Number:
MFCD01821204
MOL File:
702-82-9.mol
MSDS File:
SDS
Last updated:2026-05-28 02:51:18
Request For Quotation

3-Amino-1-adamantanol Properties

Melting point 265 °C (dec.)(lit.)
Boiling point 266.8±23.0 °C(Predicted)
Density 1.252±0.06 g/cm3(Predicted)
Flash point 230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
pka 15.07±0.40(Predicted)
color White to yellow
Water Solubility Soluble in organic solvents,insoluble in water.
InChI InChI=1S/C10H17NO/c11-9-2-7-1-8(3-9)5-10(12,4-7)6-9/h7-8,12H,1-6,11H2
InChIKey DWPIPTNBOVJYAD-UHFFFAOYSA-N
SMILES C12(O)CC3CC(CC(N)(C3)C1)C2
CAS DataBase Reference 702-82-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29221990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
1
2 0

3-Amino-1-adamantanol price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 523690 3-Amino-1-adamantanol 96% 702-82-9 1g $28.5 2026-04-30 Buy
Sigma-Aldrich 523690 3-Amino-1-adamantanol 96% 702-82-9 5g $43.9 2026-04-30 Buy
TCI Chemical A2079 3-Amino-1-adamantanol Hydrate >98.0%(GC)(T) 702-82-9 1g $19 2026-04-30 Buy
TCI Chemical A2079 3-Amino-1-adamantanol Hydrate >98.0%(GC)(T) 702-82-9 5g $43 2026-04-30 Buy
TRC TRC-A580300-5G 1-Amino-3-adamantanol >95%(HPLC) 702-82-9 5g $384 2026-06-03 Buy
Product number Packaging Price Buy
523690 1g $28.5 Buy
523690 5g $43.9 Buy
A2079 1g $19 Buy
A2079 5g $43 Buy
TRC-A580300-5G 5g $384 Buy

3-Amino-1-adamantanol Chemical Properties,Uses,Production

Description

3-Amino-1-adamantanol is an important adamantane drug intermediate mainly used in the synthesis of inhibitors with antihyperglycaemic properties for the preparation of Vildagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor used in the treatment of type 2 diabetes.

Chemical Properties

White solid

Uses

It is employed in the synthesis of inhibitors with antihyperglycemic properties. vil- dagliptin is synthesised from 3-Amino-1-adamantanol.

Uses

As reagent, 3-Amino-1-hydroxyadamantane can be used in the preparation of Vildagliptin.

Uses

3-Amino-1-hydroxyadamantane can be employed in the synthesis of inhibitors with antihyperglycemic properties.

Synthesis

A preparation method of 3-amino-1-adamantanol comprises the following steps: (1) adding amantadine or a salt thereof to sulfuric acid at 10-30°C and adding a mixed acid dropwise to perform a nitration reaction to obtain a reaction liquid; (2) adding the reaction liquid to water and mixing the reaction liquid with water to obtain a mixed solution; (3) performing a hydroxylation reaction under the effect of alkaline to obtain the 3-amino-1-adamantanol. The preparation method employs the raw material, is easy to obtain, is simple in operations, is environmentally protective, is low in cost, and is high in yield, which is generally higher than 80%, maximally 90.1%.

References

[1] Pharmaceutical Chemistry Journal, 1990, vol. 24, # 1, p. 35 - 39
[2] Khimiko-Farmatsevticheskii Zhurnal, 1990, vol. 24, # 1, p. 29 - 31
[3] Tetrahedron Letters, 2017, vol. 58, # 15, p. 1456 - 1458
[4] Journal of Medicinal Chemistry, 2016, vol. 59, # 3, p. 947 - 964
[5] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 554 - 564

3-Amino-1-adamantanol Preparation Products And Raw materials

Raw materials

Vildagliptin Impurity 19 1-Adamantanamine hydrochloride Amantadine

Preparation Products

3-Amino-1-adamantanol Suppliers

Global( 667)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan Zhongbang Pharma CO.，LTD 0830-0830-2585019 13679670161 sales2@zhongbangst.com China 105 69
TIANJIN MINXIANG BIOMEDICAL INC. 13313219033 tjmx@mxpharm.com China 39 58
Wuxi Hailun Bio-Technology Co., Ltd. 0510-85629785 18051595327; sales@hlsw-bio.com China 101 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14072 58
Huzhou Chenxi Environmental Protection Technology Co., Ltd. 16762203950 16762203950 3775386035@qq.com China 102 58
Hefei Ruiluo New Material Technology Co., Ltd. 19567218739 1759672789@qq.com China 569 58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD. 022-60189726 18812034280 188120342808@163.com China 143 61
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Supplier Advantage
Sichuan Zhongbang Pharma CO.，LTD 69
TIANJIN MINXIANG BIOMEDICAL INC. 58
Wuxi Hailun Bio-Technology Co., Ltd. 58
Wuxi Helen Biotechnology Co., Ltd., 58
Huzhou Chenxi Environmental Protection Technology Co., Ltd. 58
Hefei Ruiluo New Material Technology Co., Ltd. 58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD. 61
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66

Related articles

View Lastest Price from 3-Amino-1-adamantanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Amino-1-hydroxyadamantane pictures 2026-09-13 3-Amino-1-hydroxyadamantane
702-82-9
 0.99 RongNa Biotechnology Co.,Ltd
3-Amino-1-adamantanol pictures 2026-09-11 3-Amino-1-adamantanol
702-82-9
 $66.00-99.00 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
3-Amino-1-hydroxyadamantane pictures 2026-09-11 3-Amino-1-hydroxyadamantane
702-82-9
 1kg 99%min GC 1000kg WUHAN FORTUNA CHEMICAL CO., LTD

3-Amino-1-adamantanol Spectrum

3-Amino-1-adamantanol(702-82-9)1HNMR3-Amino-1-adamantanol(702-82-9)IR

702-82-9(3-Amino-1-adamantanol)Related Search:

PotassiuM sodiuM Dehydroandrographolide Succinate 1-Adamantanol Altrenogest Amantadine Adamantane
Betaine 3-Amino-1-propanesulfonic acid 3-Amino-1,2-propanediol Glycine Aminoethoxyvinyl glycine hydrochloride
N-acetic acid-1-aMino-3-adaMantanol Vildagliptin IMpurity 2 (Mixture of DiastereoMers) Vildagliptin Impurity 6 Vildagliptin Impurity 25 Dichloroacetyl chloride
Vildagliptin Impurity 19 1,3,5,7-tetrahydroxyadamantane 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI)

1of4

CHEMBRDG-BB 4003530 3-AMINO-1-ADAMANTANOL AKOS BB-9784 1-AMINO-3-ADAMANTANOL 1-AMINO-3-HYDROXYADAMANTANE TRICYCLO[3.3.1.13,7]DECAN-1-OL, 3-AMINO- Vigliptin impurity 15 (5r,7s)-3-aminoadamantan-1-ol 3-Amino-1-adamantanol Hydrate 3-aminoadamantan-1-ol(SALTDATA: HCl) Vildagliptin Intermediate 1 1-AMino adaMantane-3-ol 3-AMino-1-adaMantanole 3 (3-HydroxyadaMantan-1-yl)aMine 3-AMino-tricyclo[3.3.1.13,7]decan-1-ol 3-AMino-1-adaMantanol, 98+% 3-Aminoadamantan-1-ol, 3-Aminotricyclo[3.3.1.1~3,7~]decan-1-ol, 3-Hydroxytricyclo[3.3.1.1~3,7~]decan-1-amine Vildagliptin Amino Alcohol Impurity 3-AMino-1-HydroxyadaMantane SynonyMs: 3-AMinoadaMantan-1-ol 3-AMino-1-adaMantano, 98% 3 - aMino adaMantane alcohol 3-Amino-1-hydroxyadamantane 3-Aminoadamantan-1-ol 3-Amino-1-adamantanol 3-Amino-1-adamantanol 3-aminoadamantan-1-ol hydrochloride Vildagliptin Impurity 24 3-Amino-1-hydroxyadamantane (Vildagliptin) 3-Amino-1-adamantanol Hydrate> 3-amino-1-amantadine 3-Amino-1-hydroxyadamantane USP/EP/BP Vildagliptin Impurity 74 Vildagliptin Amino Alcohol Impurity/Vildagliptin Impurity 15 3-Amino-1-Adamantanamine Vildagliptin VLN-01(3-Hydroxy-1-adamantan amine) Vildagliptin Amino Alcohol ImpurityQ: What is Vildagliptin Amino Alcohol Impurity Q: What is the CAS Number of Vildagliptin Amino Alcohol Impurity Q: What is the storage condition of Vildagliptin Amino Alcohol Impurity Q: What are the applications of Vildagliptin Amino Alcohol Impurity 3-AMINO-1-ADAMNANOL 3-Amino -1-Adamantol 2-Amino-1-Hydroxyadamantane 3-amino-1-hydroxy Ademantane 1-Amino-3- Admatanol C1oH17NO 3-Amino-1-Adamentanol Vildagliptin Amino Alcohol Impurity 1-Amino-3-adamantanol 3-Aminoadamantan-ol Vildagliptin Impurity: 1-Amino-3-adamantanol 3-Amino-1-hydroxyadamantane 3-Amino-1-admantanol 3-AMINOADAMANTAN-1-OL 3-Hydroxy-1-aminoadamantane 4-aminoadamantan-1-ol 3-Aminoadamantan-1-ol , 3-Amino-1-adamantanol 702-82-9 02-82-9 702-82-7 702-89-2 C10H18NO C10H17NOxH2O C10H17NOH2O Building Blocks