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ChemicalBook >> CAS DataBase List >>2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]-

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]-

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- Structure
2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- structure
CAS No.
178165-43-0
Chemical Name:
2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]-
Synonyms
EMD-95885;2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]-
CBNumber:
CB58760804
Molecular Formula:
C22H23FN2O3
Molecular Weight:
382.43
MDL Number:
MOL File:
178165-43-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:11
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2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- Properties

Density 1.249±0.06 g/cm3(Predicted)
form Solid
pka 8.74±0.70(Predicted)
color White to off-white

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1241986 EMD-95885 98.74% 178165-43-0 5mg $290 2026-06-04 Buy
ChemScene CS-1241986 EMD-95885 98.74% 178165-43-0 10mg $460 2026-06-04 Buy
ChemScene CS-1241986 EMD-95885 98.74% 178165-43-0 25mg $915 2026-06-04 Buy
ChemScene CS-1241986 EMD-95885 98.74% 178165-43-0 50mg $1408 2026-06-04 Buy
ChemScene CS-1241986 EMD-95885 98.74% 178165-43-0 100mg $2112 2026-06-04 Buy
Product number Packaging Price Buy
CS-1241986 5mg $290 Buy
CS-1241986 10mg $460 Buy
CS-1241986 25mg $915 Buy
CS-1241986 50mg $1408 Buy
CS-1241986 100mg $2112 Buy

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- Chemical Properties,Uses,Production

Uses

EMD-95885 is a selective NR2B-containing NMDA receptors antagonist with an IC50 of 3.9 nM. EMD-95885 does not interact with other sites on the NMDA receptor[1].

IC 50

NR2B: 3.9 nM (IC50)

References

[1] Roger G, et al. Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors. Bioorg Med Chem. 2004 Jun 15;12(12):3229-37. DOI:10.1016/j.bmc.2004.03.065

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
TargetMol 58

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2(3H)-Benzoxazolone, 6-[3-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]-1-oxopropyl]- EMD-95885 178165-43-0