[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester
- CAS No.
- 2308497-81-4
- Chemical Name:
- [1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester
- Synonyms
- Boc-bipiperidine-ethynylbenzoic acid;4-((1'-(tert-Butoxycarbonyl)-[1,4'-bipiperidin]-4-yl)ethynyl)benzoic acid;4-((1'-(tert-Butoxycarbonyl)-[1,4'-bipiperidin]-4-yl)ethynyl)benzoic acid;[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester
- CBNumber:
- CB59834892
- Molecular Formula:
- C24H32N2O4
- Molecular Weight:
- 412.52
- MDL Number:
- MOL File:
- 2308497-81-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0226675 | Boc-bipiperidine-ethynylbenzoic acid 99.19% | 2308497-81-4 | 50mg | $60 | 2026-06-04 | Buy |
| ChemScene | CS-0226675 | Boc-bipiperidine-ethynylbenzoic acid 99.19% | 2308497-81-4 | 100mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0226675 | Boc-bipiperidine-ethynylbenzoic acid 99.19% | 2308497-81-4 | 250mg | $195 | 2026-06-04 | Buy |
| ChemScene | CS-0226675 | Boc-bipiperidine-ethynylbenzoic acid 99.19% | 2308497-81-4 | 500mg | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0226675 | Boc-bipiperidine-ethynylbenzoic acid 99.19% | 2308497-81-4 | 1g | $487 | 2026-06-04 | Buy |
[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester Chemical Properties,Uses,Production
Uses
Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61[1]. Boc-bipiperidine-ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Alkyl/ether
References
[1] Lijie Zhao, et al. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020 Oct;22(10):522-532. DOI:10.1016/j.neo.2020.07.002
[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester Preparation Products And Raw materials
Raw materials
Preparation Products
[1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Wuhan Yuxiang Medical Technology Co., Ltd. | 13971275651 | sales@whyxpharma.com | China | 1831 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| Bide Pharmatech Ltd. | 58 |
| Wuhan Yuxiang Medical Technology Co., Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from [1,4'-Bipiperidine]-1'-carboxylic acid, 4-[2-(4-carboxyphenyl)ethynyl]-, 1'-(1,1-dimethylethyl) ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-15 | Boc-bipiperidine-ethynylbenzoic acid
2308497-81-4
|
$74.00 | 10g | TargetMol Chemicals Inc. |
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- Boc-bipiperidine-ethynylbenzoic acid
2308497-81-4
- $74.00
- TargetMol Chemicals Inc.





