3-Trifluoromethylbenzylcyanide
- CAS No.
- 2338-76-3
- Chemical Name:
- 3-Trifluoromethylbenzylcyanide
- Synonyms
- 3-(TRIFLUOROMETHYL)PHENYLACETONITRILE;3-Trifluormethylbenzylcyanide;3-TRIFLUOROMETHYLBENZYLNITRILE;M-TRIFLUOROMETHYLBENZYL CYANIDE;3-(TRIFLUOROMETHYL)BENZYL CYANIDE;Trifluoromethyl benzene acetonitrile;3-(Trifluoromethyl)ohenylacetonitrile;M-(TRIFLUOROMETHYL)PHENYLACETONITRILE;(a,a,a-Trifluoro-m-tolyl)acetonitrile;META-TRIFLUOROMETHYLPHENYLACETONITRILE
- CBNumber:
- CB6130989
- Molecular Formula:
- C9H6F3N
- Molecular Weight:
- 185.15
- MDL Number:
- MFCD00001913
- MOL File:
- 2338-76-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 92-93 °C4 mm Hg(lit.) |
|---|---|
| Density | 1.187 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 120 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 1.187 |
| BRN | 909640 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| InChI | InChI=1S/C9H6F3N/c10-9(11,12)8-3-1-2-7(6-8)4-5-13/h1-3,6H,4H2 |
| InChIKey | JOIYKSLWXLFGGR-UHFFFAOYSA-N |
| SMILES | C1(CC#N)=CC=CC(C(F)(F)F)=C1 |
| CAS DataBase Reference | 2338-76-3(CAS DataBase Reference) |
| FDA UNII | Z3BI56GK28 |
| NIST Chemistry Reference | Benzeneacetonitrile, 3-(trifluoromethyl)-(2338-76-3) |
| EPA Substance Registry System | Benzeneacetonitrile, 3-(trifluoromethyl)- (2338-76-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 10-20/21/22-36/37/38 | |||||||||
| Safety Statements | 16-26-27-36/37/39 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CY1820000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
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| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3-Trifluoromethylbenzylcyanide price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 199192 | 3-(Trifluoromethyl)phenylacetonitrile 97% | 2338-76-3 | 10g | $55.3 | 2026-04-30 | Buy |
| TCI Chemical | T2367 | 3-(Trifluoromethyl)phenylacetonitrile >98.0%(GC) | 2338-76-3 | 5g | $33 | 2026-04-30 | Buy |
| TCI Chemical | T2367 | 3-(Trifluoromethyl)phenylacetonitrile >98.0%(GC) | 2338-76-3 | 25g | $101 | 2026-04-30 | Buy |
| Usbiological | 290975 | 3-Trifluoromethylphenylacetonitrile Asreported | 2338-76-3 | 25g | $340 | 2026-06-03 | Buy |
| Usbiological | 290975 | 3-Trifluoromethylphenylacetonitrile Asreported | 2338-76-3 | 50g | $460 | 2026-06-03 | Buy |
3-Trifluoromethylbenzylcyanide Chemical Properties, Uses, Production
Chemical Properties
CLEAR YELLOW-BROWN LIQUID
Uses
3-(Trifluoromethyl)phenylacetonitrile may be used in chemical synthesis studies.
Synthesis
773837-37-9
705-29-3
2338-76-3
The general procedure for the synthesis of m-trifluoromethylphenylacetonitrile from the compound (CAS: 773837-37-9) and 3-trifluoromethylbenzyl chloride was as follows: An aqueous solution of sodium cyanide was prepared by adding 61.7 g of sodium cyanide and 112 g of water to a 250 mL beaker and stirring for 2 h until completely dissolved. Add 235 g of 2,3-trifluoromethylbenzyl chloride and 2.5 g of triethylbenzylammonium chloride to a 500 mL three-necked flask, and heat to 60°C. The temperature is controlled at 55~65°C. The aqueous sodium cyanide solution prepared above was slowly added dropwise under the temperature control of 55~65°C. After the dropwise addition was completed, the reaction temperature was maintained at 60°C for 8 hours. Samples were taken for HPLC analysis during the reaction to ensure that the mass fraction of 3-trifluoromethylbenzyl chloride was less than 0.5%. After completion of the reaction, it was cooled to room temperature and left to stratify. The aqueous layer was washed twice with 50 g of water, all aqueous layers were combined and treated with 5% sodium hypochlorite solution. The oil layer was distilled under reduced pressure and the 94-97 °C fraction was collected at -0.095 MPa to give 204 g of m-trifluoromethylbenzylacetonitrile with a product purity ≥94.0% and a yield of 91%.
References
[1] Patent: CN106349006, 2017, A. Location in patent: Paragraph 0007; 0024; 0037
3-Trifluoromethylbenzylcyanide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Hongyuan Chemical Technology Co., LTD | 13561560789 | xinxiaoxiao2008@126.com | China | 1005 | 58 |
| Beijing Century Richap Chemistry Co., Ltd. | 010-64446226 13146983882 | info@bj-newcenturychem.com | China | 111 | 55 |
| Jinan Junhe Pharmaceutical Co., Ltd | 18653300596 | 3989432235@qq.com | China | 298 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
View Latest Price from 3-Trifluoromethylbenzylcyanide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-24 | 3-Trifluoromethylbenzylcyanide
2338-76-3
|
1KG | ≥98% | 200mt/year | Jinan Finer Chemical Co., Ltd | ||
 |
2026-09-02 | 3-(Trifluoromethyl)benzyl cyanide
2338-76-3
|
$8.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-28 | 3-Trifluoromethylbenzylcyanide
2338-76-3
|
$9.00 | 1KG | 99.8% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 3-Trifluoromethylbenzylcyanide
2338-76-3
- $0.00
- ≥98%
- Jinan Finer Chemical Co., Ltd
-
- 3-(Trifluoromethyl)benzyl cyanide
2338-76-3
- $8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Trifluoromethylbenzylcyanide
2338-76-3
- $9.00
- 99.8%
- Hebei Chuanghai Biotechnology Co,.LTD
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