Dopamine D4 receptor antagonist-1
- CAS No.
- 444724-92-9
- Chemical Name:
- Dopamine D4 receptor antagonist-1
- Synonyms
- Dopamine D4 receptor antagonist-1
- CBNumber:
- CB613259291
- Molecular Formula:
- C18H19ClN4
- Molecular Weight:
- 326.83
- MDL Number:
- MOL File:
- 444724-92-9.mol
- MSDS File:
- SDS
Dopamine D4 receptor antagonist-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0568621 | Dopamine D4 receptor antagonist-1 98.59% | 444724-92-9 | 5mg | $179 | 2026-06-04 | Buy |
| aablocks | AA02ADTH | 2-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole >98% | 444724-92-9 | 5mg | $219 | 2026-06-02 | Buy |
Dopamine D4 receptor antagonist-1 Chemical Properties, Uses, Production
Uses
Dopamine D4 receptor antagonist-1 is a selective DRD4 antagonists, with a Ki of 9.0 nM for Hd4.2. Dopamine D4 receptor antagonist-1 can be used in study of schizophrenia[1].
in vivo
Dopamine D4 receptor antagonist-1 (10 mg/kg; i.p.; single) shows inhibitory effect on catecholaminergic systems (DOPA accumulation in the hippocampus)[1].
| Animal Model: | Male Long-Evans rats (180-250 g); knockout of the DA D4 receptor locus mice (D4 KO); wild type rats (WT)[1]. |
| Dosage: | 10 mg/kg |
| Administration: | Intraperitoneal injection, single. |
| Result: | Increased DOPA accumulation in the hippocampus with no effect observed in the striatum. |
IC 50
hD4.2 Receptor: 9.0 nM (Ki)
References
[1] Pugsley TA, et al. The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):219-26. DOI:10.1016/s0278-5846(01)00252-4
Dopamine D4 receptor antagonist-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Dopamine D4 receptor antagonist-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29873 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from Dopamine D4 receptor antagonist-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | Dopamine D4 receptor antagonist-1
444724-92-9
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Dopamine D4 receptor antagonist-1
444724-92-9
- $1520.00-2500.00
- TargetMol Chemicals Inc.
