ChemicalBook >> CAS DataBase List >>Clinafloxacin
Clinafloxacin
- CAS No.
- 105956-97-6
- Chemical Name:
- Clinafloxacin
- Synonyms
- CI-960;PD-127391;Aids007759;Aids-007759;Clinfloxacin;CLINAFLOXACIN;Colinflosaxin;Clinofloxacin;Clinafloxacin (AM-1091;Clinafloxacin USP/EP/BP
- CBNumber:
- CB6148236
- Molecular Formula:
- C17H17ClFN3O3
- Molecular Weight:
- 365.79
- MDL Number:
- MFCD00865120
- MOL File:
- 105956-97-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-14 16:49:18
| Product description | Number | Pack Size | Price |
| Clinafloxacin | TRC-C579003-50MG | 50mg | $227 |
| Clinafloxacin | TRC-C579003-10MG | 10mg | $70 |
| Clinafloxacin | TRC-C579003-100MG | 100mg | $380 |
| Clinafloxacin 99.87% | CS-2633 | 5mg | $38 |
| Clinafloxacin 99.87% | CS-2633 | 10mg | $60 |
| More product size | |||
| Melting point | 253-258 C |
|---|---|
| Boiling point | 592.3±50.0 °C(Predicted) |
| Density | 1.573±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Acetic Acid (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 6.39±0.50(Predicted) |
| color | Pale Beige |
| InChI | InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25) |
| InChIKey | QGPKADBNRMWEQR-UHFFFAOYSA-N |
| SMILES | N1(C2CC2)C2=C(C=C(F)C(N3CCC(N)C3)=C2Cl)C(=O)C(C(O)=O)=C1 |
| CAS DataBase Reference | 105956-97-6(CAS DataBase Reference) |
| FDA UNII | 8N86XTF9QD |
| EPA Substance Registry System | Clinafloxacin (105956-97-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361d |
| Precautionary statements | P281 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-63 |
| Safety Statements | 26-36-36/37 |
| RTECS | VB1800600 |
Clinafloxacin price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C579003-50MG | Clinafloxacin | 105956-97-6 | 50mg | $227 | 2026-06-03 | Buy |
| TRC | TRC-C579003-10MG | Clinafloxacin | 105956-97-6 | 10mg | $70 | 2026-06-03 | Buy |
| TRC | TRC-C579003-100MG | Clinafloxacin | 105956-97-6 | 100mg | $380 | 2026-06-03 | Buy |
| ChemScene | CS-2633 | Clinafloxacin 99.87% | 105956-97-6 | 5mg | $38 | 2026-06-04 | Buy |
| ChemScene | CS-2633 | Clinafloxacin 99.87% | 105956-97-6 | 10mg | $60 | 2026-06-04 | Buy |
Clinafloxacin Chemical Properties,Uses,Production
Uses
Antibacterial.
Uses
Clinafloxacin is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV.
Definition
ChEBI: 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid is a member of quinolines.
in vivo
Clinafloxacin is very effective for the therapy of penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis in the rabbit model. With the CS strain (2349)(Clinafloxacin MIC=0.12 μg/ml), at a dose of 10 mg/kg and 20 mg/kg per day Clinafloxacin achieves an initial reduction at 6 hr. Both are bactericidal at this point but presents regrowth at 24 hr, and the final reduction at 24 hr in mean log cfu/ml is 22.30 and 23.83, respectively. However, With the CR strain (4371)(Clinafloxacin MIC=0.5 μg/ml), Clinafloxacin even at 20 mg/kg per day does not decrease bacterial titers at any time point in this rabbit model of meningitis[3].
IC 50
Quinolone
Synthesis of Clinafloxacin from 8-Chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Clinafloxacin Preparation Products And Raw materials
Raw materials
A mixture of: (R)-7-[3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid: (S)-7-[3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid
8-Chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
3-Aminopyrrolidine
Triethylenediamine
2-Methoxyethanol
1of2
Preparation Products
Global( 200)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +86-519-85525359 +86-15995072465 | sales@xuanmingchem.com | China | 912 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29094 | 58 |
View Lastest Price from Clinafloxacin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Clinafloxacin
105956-97-6
|
$44.00-113.00 | 98.30% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-14 | Clinafloxacin
105956-97-6
|
$44.00-113.00 | 98.30% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-11-18 | Clinafloxacin USP/EP/BP
105956-97-6
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Clinafloxacin
105956-97-6
- $44.00-113.00
- 98.30%
- TargetMol Chemicals Inc.
-
- Clinafloxacin
105956-97-6
- $44.00-113.00
- 98.30%
- TargetMol Chemicals Inc.
-
- Clinafloxacin USP/EP/BP
105956-97-6
- $1.10
- 99.9%
- Dideu Industries Group Limited
105956-97-6(Clinafloxacin)Related Search:
1of4
3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
6-Fluoro-8-chloro-1-cyclopropyl-7-(3-aminopyrrolidin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CI-960
PD-127391
7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
Aids007759
Aids-007759
7-(3-AMinopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CLINAFLOXACIN
7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxyli
7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid
Clinafloxacin CI96 AM1091
7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbox
7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-Quinolin-3-carboxylic acid
7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydroxy-4-oxo-3-quinolinecarboxylic acid
Colinflosaxin
Clindamycin hydrochloride`Clinafloxacin
Clinafloxacin USP/EP/BP
Clinafloxacin (AM-1091
Clinfloxacin
ClinafloxacinQ: What is
Clinafloxacin Q: What is the CAS Number of
Clinafloxacin
Clinofloxacin
Clinafloxacin in MeOH with 0.04M NaOH
105956-97-6
C17H17ClFN3O3
