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Clinafloxacin

Clinafloxacin Structure
Clinafloxacin structure
CAS No.
105956-97-6
Chemical Name:
Clinafloxacin
Synonyms
CI-960;PD-127391;Aids007759;Aids-007759;Clinfloxacin;CLINAFLOXACIN;Colinflosaxin;Clinofloxacin;Clinafloxacin (AM-1091;Clinafloxacin USP/EP/BP
CBNumber:
CB6148236
Molecular Formula:
C17H17ClFN3O3
Molecular Weight:
365.79
MDL Number:
MFCD00865120
MOL File:
105956-97-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-06 14:26:04
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Clinafloxacin Properties

Melting point 253-258 C
Boiling point 592.3±50.0 °C(Predicted)
Density 1.573±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Acetic Acid (Slightly), DMSO (Slightly)
form Solid
pka 6.39±0.50(Predicted)
color Pale Beige
InChI InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25)
InChIKey QGPKADBNRMWEQR-UHFFFAOYSA-N
SMILES N1(C2CC2)C2=C(C=C(F)C(N3CCC(N)C3)=C2Cl)C(=O)C(C(O)=O)=C1
CAS DataBase Reference 105956-97-6(CAS DataBase Reference)
FDA UNII 8N86XTF9QD
EPA Substance Registry System Clinafloxacin (105956-97-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H361d
Precautionary statements  P281
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-63
Safety Statements  26-36-36/37
RTECS  VB1800600

Clinafloxacin price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-C579003-50MG Clinafloxacin 105956-97-6 50mg $227 2026-06-03 Buy
TRC TRC-C579003-10MG Clinafloxacin 105956-97-6 10mg $70 2026-06-03 Buy
TRC TRC-C579003-100MG Clinafloxacin 105956-97-6 100mg $380 2026-06-03 Buy
ChemScene CS-2633 Clinafloxacin 99.87% 105956-97-6 5mg $38 2026-06-04 Buy
ChemScene CS-2633 Clinafloxacin 99.87% 105956-97-6 10mg $60 2026-06-04 Buy
Product number Packaging Price Buy
TRC-C579003-50MG 50mg $227 Buy
TRC-C579003-10MG 10mg $70 Buy
TRC-C579003-100MG 100mg $380 Buy
CS-2633 5mg $38 Buy
CS-2633 10mg $60 Buy

Clinafloxacin Chemical Properties, Uses, Production

Uses

Antibacterial.

Uses

Clinafloxacin is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV.

Definition

ChEBI: 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid is a member of quinolines.

in vivo

Clinafloxacin is very effective for the therapy of penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis in the rabbit model. With the CS strain (2349)(Clinafloxacin MIC=0.12 μg/ml), at a dose of 10 mg/kg and 20 mg/kg per day Clinafloxacin achieves an initial reduction at 6 hr. Both are bactericidal at this point but presents regrowth at 24 hr, and the final reduction at 24 hr in mean log cfu/ml is 22.30 and 23.83, respectively. However, With the CR strain (4371)(Clinafloxacin MIC=0.5 μg/ml), Clinafloxacin even at 20 mg/kg per day does not decrease bacterial titers at any time point in this rabbit model of meningitis[3].

IC 50

Quinolone

Clinafloxacin synthesis

101987-89-7
105956-97-6
Synthesis of Clinafloxacin from 8-Chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Clinafloxacin Preparation Products And Raw materials

Raw materials

A mixture of: (R)-7-[3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid: (S)-7-[3-(tert-butoxycarbonylamino)pyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid 8-Chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 3-Aminopyrrolidine Triethylenediamine 2-Methoxyethanol
Pivaldehyde

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Preparation Products

Clinafloxacin Suppliers

Global Suppliers ( 199)
Supplier Tel Email Country ProdList Advantage
Hubei Yihao Biotechnology Co., Ltd. 18995688786 156716255@qq.com China 260 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 997 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Supplier Advantage
Hubei Yihao Biotechnology Co., Ltd. 58
Chembest Research Laboratories Limited 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Dalian Meilun Biotech Co., Ltd. 58
Shanghai T&W Pharmaceutical Co., Ltd. 58
Haoyuan Chemexpress Co., Ltd. 61
UHN Shanghai Research & Development Co., Ltd. 58
MedChemexpress LLC 58
Guangzhou Isun Pharmaceutical Co., Ltd 55
TargetMol Chemicals Inc. 58

View Latest Price from Clinafloxacin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Clinafloxacin USP/EP/BP pictures 2026-08-20 Clinafloxacin USP/EP/BP
105956-97-6
 $1.10 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Clinafloxacin pictures 2026-08-07 Clinafloxacin
105956-97-6
 1KG 99% 1000kgs Shaanxi Dideu New Materials Co. Ltd
Clinafloxacin pictures 2026-07-14 Clinafloxacin
105956-97-6
 $44.00-113.00 98.30% 10g TargetMol Chemicals Inc.
  • Clinafloxacin pictures
  • Clinafloxacin
    105956-97-6
  • $0.00
  • 99%
  • Shaanxi Dideu New Materials Co. Ltd
  • Clinafloxacin pictures
  • Clinafloxacin
    105956-97-6
  • $44.00-113.00
  • 98.30%
  • TargetMol Chemicals Inc.

Clinafloxacin Spectrum

Clinafloxacin(105956-97-6)1HNMR

105956-97-6 (Clinafloxacin) Related Search:

TROVAFLOXACIN Quinhydrone N-Methyl-2-pyrrolidone Clindamycin 6-Aminocaproic acid
Povidone iodine N-Vinyl-2-pyrrolidone Quinclorac Ethoxyquin Clindamycin phosphate
Gatifloxacin Gemifioxacin Tris(hydroxymethyl)aminomethane Glycine Polyvinylpyrrolidone
Aminoethoxyvinyl glycine hydrochloride Clindamycin hydrochloride Sparfloxacin

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3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- 6-Fluoro-8-chloro-1-cyclopropyl-7-(3-aminopyrrolidin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid CI-960 PD-127391 7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride Aids007759 Aids-007759 7-(3-AMinopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CLINAFLOXACIN 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxyli 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid Clinafloxacin CI96 AM1091 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbox 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-Quinolin-3-carboxylic acid 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydroxy-4-oxo-3-quinolinecarboxylic acid Colinflosaxin Clindamycin hydrochloride`Clinafloxacin Clinafloxacin USP/EP/BP Clinafloxacin (AM-1091 Clinfloxacin ClinafloxacinQ: What is Clinafloxacin Q: What is the CAS Number of Clinafloxacin Clinofloxacin Clinafloxacin in MeOH with 0.04M NaOH 105956-97-6 C17H17ClFN3O3