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Ethyl 2,2-dimethylphenylacetate

CAS No.
2901-13-5
Chemical Name:
Ethyl 2,2-dimethylphenylacetate
Synonyms
Ethyl Dimethylphenylacetate;NSC 29060;2-dimethylphenylacetate;Ethyl 2-phenylisobutyrate;ETHYL DIMETHYLBENZENEACETATE;Ethyl Dimethylbenzeneacetatee;ETHYL 2,2-DIMETHYLPHENYLACETATE;Ethyl a,a-Dimethylphenylacetate;Ethyl a,a-Dimethylbenzeneacetate;Ethyl 2,2-diMethylbenzeneacetate
CBNumber:
CB6156301
Molecular Formula:
C12H16O2
Molecular Weight:
192.25
MDL Number:
MFCD03844687
MOL File:
2901-13-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:54:27
Product description Number Pack Size Price
Ethyl dimethylbenzeneacetate 98% OR963290 25g $39
Ethyl dimethylbenzeneacetate 98% OR963290 100g $131
Ethyl dimethylbenzeneacetate 98% OR963290 500g $627
Ethyl dimethylbenzeneacetate 98% OR963290 25g $39
Ethyl dimethylbenzeneacetate 98% OR963290 100g $131
More product size

Ethyl 2,2-dimethylphenylacetate Properties

Boiling point 68-71 °C(Press: 0.5-0.6 Torr)
Density 1.0039 g/cm3
vapor pressure 10-1013.3hPa at 96.5-234.3℃
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
color Clear Colourless to Pale Yellow
LogP 3.5
Surface tension 5.92mN/m at 159.4mg/L and 20℃
CAS DataBase Reference 2901-13-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
HS Code  2916399090
REACH Registrations Active

Ethyl 2,2-dimethylphenylacetate price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR963290 Ethyl dimethylbenzeneacetate 98% 2901-13-5 25g $39 2026-06-04 Buy
Apolloscientific OR963290 Ethyl dimethylbenzeneacetate 98% 2901-13-5 100g $131 2026-06-04 Buy
Apolloscientific OR963290 Ethyl dimethylbenzeneacetate 98% 2901-13-5 500g $627 2026-06-04 Buy
Apolloscientific OR963290 Ethyl dimethylbenzeneacetate 98% 2901-13-5 25g $39 2026-06-04 Buy
Apolloscientific OR963290 Ethyl dimethylbenzeneacetate 98% 2901-13-5 100g $131 2026-06-04 Buy
Product number Packaging Price Buy
OR963290 25g $39 Buy
OR963290 100g $131 Buy
OR963290 500g $627 Buy
OR963290 25g $39 Buy
OR963290 100g $131 Buy

Ethyl 2,2-dimethylphenylacetate Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Liquid

Uses

Ethyl Dimethylphenylacetate (cas# 2901-13-5) is a compound useful in organic synthesis.

Synthesis

Ethanol

64-17-5

2-Phenylisobutyric acid

826-55-1

Ethyl 2,2-dimethylphenylacetate

2901-13-5

Example 1: Synthesis of ethyl 2,2-dimethylphenylacetate In a 10L three-necked flask, 2-methyl-2-phenylpropanecarboxylic acid (500g, 3.1 mol) and 2.5L of dichloromethane were added and dissolved with stirring at room temperature. Subsequently, thionyl chloride (750 g, 6.3 mol) was added slowly, and after addition, the reaction system was heated to reflux and maintained for 15 hours. After the reaction was completed, cooled to room temperature, 400mL of anhydrous ethanol was added slowly dropwise, and stirring was continued for 2 hours after the dropwise addition. The reaction solution was adjusted to pH 9-10 with 10% NaOH solution and the completion of the reaction was monitored by thin layer chromatography (TLC). The organic layer was separated, washed twice each with saturated sodium bicarbonate solution and saturated sodium chloride solution in turn, and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give a colorless oily product, ethyl 2,2-dimethylbenzeneacetate 560 g, 96% yield.

References

[1] Patent: CN104276952, 2016, B. Location in patent: Paragraph 0027; 0028
[2] MedChemComm, 2013, vol. 4, # 2, p. 367 - 370
[3] Tetrahedron, 2009, vol. 65, # 2, p. 456 - 460
[4] Journal of the American Chemical Society, 1968, vol. 90, p. 2082 - 2096
[5] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001, vol. 40, # 8, p. 717 - 718

Ethyl 2,2-dimethylphenylacetate Preparation Products And Raw materials

Global( 115)Suppliers
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View Lastest Price from Ethyl 2,2-dimethylphenylacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 2,2-dimethylphenylacetate pictures 2019-12-26 Ethyl 2,2-dimethylphenylacetate
2901-13-5
$1.00 1KG 99% 100KG Career Henan Chemical Co

Ethyl 2,2-dimethylphenylacetate Spectrum

ETHYL DIMETHYLBENZENEACETATE ETHYL 2,2-DIMETHYLPHENYLACETATE a,a-Dimethyl-benzeneacetic Acid Ethyl Ester a-methyl-hydratropic Acid Ethyl Ester Ethyl 2-phenylisobutyrate Ethyl a,a-Dimethylbenzeneacetate Ethyl a,a-Dimethylphenylacetate NSC 29060 Ethyl Dimethylbenzeneacetatee α-methyl-hydratropic Acid Ethyl Ester Benzeneacetic acid, a,a-diMethyl-, ethyl ester α,α-DiMethyl-benzeneacetic Acid Ethyl Ester Benzeneacetic acid, alpha,alpha-diMethyl-, ethyl ester ethyl 2-methyl-2-phenylpropanoate ethyl 2-methyl-2-phenyl-propanoate Ethyl 2,2-diMethylbenzeneacetate 2-(6,6-dimethyl-1-cyclohexa-2,4-dienyl)acetic acid ethyl ester Benzeneacetic acid, α,α-dimethyl-, ethyl ester 2-dimethylphenylacetate Benzeneacetic acid, α,α-dimethyl-, ethyl ester (9CI, ACI) alpha,alpha-Dimethylbenzeneacetic acid ethyl ester α,α-Dimethyl-ethyl ester benzeneacetic acid 2,2-dimethylphenylacetic acidethyl ester Ethyl Dimethylphenylacetate 2901-13-5 Aromatics Compounds Aromatics