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2-Phenylisobutyric acid

CAS No.
826-55-1
Chemical Name:
2-Phenylisobutyric acid
Synonyms
2-methyl-2-phenylpropanoic acid;TH 4161;NSC 28952;NSC 29095;α, α-diMethyl acid;RARECHEM AL BO 1659;Phenylisobutyric Aci;2- phenylisobutyrate;2-Phenylisobutyrsure;Bilastine Impurity 48
CBNumber:
CB8424536
Molecular Formula:
C10H12O2
Molecular Weight:
164.2
MDL Number:
MFCD00014332
MOL File:
826-55-1.mol
Last updated:2025-07-04 14:23:25

2-Phenylisobutyric acid Properties

Melting point 80-82°C
Boiling point 146.5°C
Density 1.089±0.06 g/cm3(Predicted)
Flash point 146.5°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 4.39±0.10(Predicted)
form Crystalline
color White
Water Solubility Insoluble in water.
InChI InChI=1S/C10H12O2/c1-10(2,9(11)12)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,11,12)
InChIKey YYEROYLAYAVZNW-UHFFFAOYSA-N
SMILES C1(=CC=CC=C1)C(C)(C)C(=O)O
LogP 2.3 at 20℃
CAS DataBase Reference 826-55-1(CAS DataBase Reference)
FDA UNII DR8HUH2GYK
UNSPSC Code 12352106

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36/37/39
HS Code  2916399090
NFPA 704
0
2 0

2-Phenylisobutyric acid price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS000391 2-Methyl-2-phenylpropanoic acid AldrichCPR 826-55-1 1G $73.1 2025-07-31 Buy
TCI Chemical P1409 2-Phenylisobutyric Acid >98.0%(GC)(T) 826-55-1 25g $89 2025-07-31 Buy
TCI Chemical P1409 2-Phenylisobutyric Acid >98.0%(GC)(T) 826-55-1 250g $532 2025-07-31 Buy
TRC P335300 2-Phenylisobutyric Acid 826-55-1 1g $110 2021-12-16 Buy
American Custom Chemicals Corporation CHM0034726 2-METHYL-2-PHENYLPROPIONIC ACID 95.00% 826-55-1 1G $704.55 2021-12-16 Buy
Product number Packaging Price Buy
CDS000391 1G $73.1 Buy
P1409 25g $89 Buy
P1409 250g $532 Buy
P335300 1g $110 Buy
CHM0034726 1G $704.55 Buy

2-Phenylisobutyric acid Chemical Properties,Uses,Production

Uses

2-Methyl-2-phenylpropionic acid is used in the synthesis of Fexofenadine hydrochloride

Uses

Used in the synthesis of Fexofenadine hydrochloride (F322470).

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1636, 1958 DOI: 10.1021/jo01105a014

201230-82-2
98-83-9
826-55-1
772-17-8
Synthesis of 2-Phenylisobutyric acid from carbon monoxide and 2-Phenyl-1-propene
Global( 359)Suppliers
Supplier Tel Email Country ProdList Advantage
CHANGZHOU HARVECHEM LTD
+86-0519-88784888 +8613906120163 inquiry@harvechem.com China 286 58
ShenZhen H&D Pharmaceutical Technology Co., LTD
+8618627948422 sale@hdimpurity.com China 3681 58
Capot Chemical Co.,Ltd.
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2988 55
career henan chemical co
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Jinan Finer Chemical Co., Ltd
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Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2176 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49730 58

View Lastest Price from 2-Phenylisobutyric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Phenylisobutyric acid pictures 2025-08-08 2-Phenylisobutyric acid
826-55-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
2-Phenylisobutyric acid pictures 2025-04-04 2-Phenylisobutyric acid
826-55-1
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Bilastine Impurity 48 pictures 2025-03-04 Bilastine Impurity 48
US $0.00-0.00 / mg 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD
RARECHEM AL BO 1659 2,2-DIMETHYLPHENYLACETIC ACID 2-METHYL-2-PHENYLPROPIONIC ACID 2-PHENYLISOBUTYRIC ACID ALPHA,ALPHA-DIMETHYLPHENYLACETIC ACID A,A-DIMETHYLPHENYLACETIC ACID A,A-DIMETHYLTOLUIC ACID DIMETHYLBENZENEACETIC ACID 2-methyl-2-phenylpropanoic acid α,α-Dimethylbenzene acid à,à-dimethylphenylacetic acid ɑ,ɑ-Dimethylphenylacetic acid α, α-diMethyl acid 2,2-DiMethyl-2-phenylacetic Acid 2-Phenyl-2-Methylpropionic Acid NSC 28952 NSC 29095 TH 4161 α-Methylhydratropic Acid .alpha.,.alpha.-Dimethylbenzeneacetic acid .alpha.-Toluic acid, .alpha.,.alpha.-dimethyl- Benzeneacetic acid, .alpha.,.alpha.-dimethyl- BETA,BETA-DIMETHYLPHENYLACETIC ACID Hydratropic acid, .alpha.-methyl- Propionic acid, 2-methyl-2-phenyl- Benzeneacetic acid, a,a-diMethyl- Phenylisobutyric Aci 2- phenylisobutyrate 2-Phenylisobutyric Acid , 98.0%(T) 2-Phenylisobutyrsure 2-(6,6-dimethyl-1-cyclohexa-2,4-dienyl)acetic acid 2-PhenylisobutyricAcid> Benzeneacetic acid, α,α-dimethyl- 2,2-Dimethyl Phenyl Acetic Acid DMPA Alpha, alpha-Dimethyl Phenyl Acetic Acid (2-Methyl-2-phenylpropionic acid) α,α-Dimethylphenyl acetic acid 2-Methyl-2-phenylpropionicaci Benzeneacetic acid, α,?α-?dimethyl- 2-mehyl-2phenyl propionic acid Bilastine Impurity 48 2-Methyl-2-phenylpropanoic acid ( DMPA ) 2-Methyl-2-phenylpropionic acid, 98% α,α-Dimethylphenylacetic acid, CAS 826-55-1 826-55-1 Aromatics Intermediates & Fine Chemicals Pharmaceuticals Acids and Derivatives