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N-Acetyl-L-glutamic acid

N-Acetyl-L-glutamic acid structure

CAS No.: 1188-37-0

Chemical Name:: N-Acetyl-L-glutamic acid

Synonyms: N-Acetylglutamic acid;N-Acetyl-L-glutamate;n-acetylglutamate;NAcGlu;AC-GLU-OH;N-AC-L-GLU;N-Ac-Glu-OH;Ac-L-Glu-OH;l-glutamicaci;N-Ac-L-Glu-OH

CBNumber:: CB6175759

Molecular Formula:: C7H11NO5

Molecular Weight:: 189.17

MDL Number:: MFCD00002802

MOL File:: 1188-37-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-03 11:24:09

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N-Acetyl-L-glutamic acid Properties

Melting point	194-196 °C(lit.)
alpha	-16 º (c=1, water)
Boiling point	324.41°C (rough estimate)
Density	1.4119 (rough estimate)
FEMA	4752 \| N-ACETYL GLUTAMATE
refractive index	-15 ° (C=1, H2O)
storage temp.	2-8°C
solubility	36g/l (Lit.)
pka	3.45±0.10(Predicted)
form	Solid
color	White
optical activity	[α]22/D 15.6°, c = 1 in H2O
Water Solubility	2.7 g/100 mL (20 ºC)
JECFA Number	2269
BRN	1727473
Major Application	peptide synthesis
Cosmetics Ingredients Functions	SKIN CONDITIONING
Cosmetic Ingredient Review (CIR)	N-Acetyl-L-glutamic acid (1188-37-0)
InChI	1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1
InChIKey	RFMMMVDNIPUKGG-YFKPBYRVSA-N
SMILES	CC(=O)N[C@@H](CCC(O)=O)C(O)=O
LogP	-2.131 (est)
CAS DataBase Reference	1188-37-0(CAS DataBase Reference)
FDA UNII	MA61H539YZ
NIST Chemistry Reference	N-acetyl-l-glutamic acid(1188-37-0)
EPA Substance Registry System	L-Glutamic acid, N-acetyl- (1188-37-0)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P271-P261-P280

Safety Statements

24/25

WGK Germany

RTECS

LZ9725000

TSCA

TSCA listed

HS Code

29241900

Storage Class

11 - Combustible Solids

REACH Registrations

Active

NFPA 704

	0
0		0

N-Acetyl-L-glutamic acid price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	855642	N-Acetyl-L-glutamic acid ReagentPlus , 99%	1188-37-0	25g	$83.3	2026-04-30	Buy
Sigma-Aldrich	855642	N-Acetyl-L-glutamic acid ReagentPlus , 99%	1188-37-0	100g	$168	2026-04-30	Buy
TCI Chemical	A0693	N-Acetyl-L-glutamic Acid >98.0%(HPLC)(T)	1188-37-0	25g	$29	2026-04-30	Buy
TCI Chemical	A0693	N-Acetyl-L-glutamic Acid >98.0%(HPLC)(T)	1188-37-0	250g	$131	2026-04-30	Buy
Cayman Chemical	37359	N-acetyl-L-Glutamic Acid ≥90%	1188-37-0	50g	$33	2026-04-30	Buy

Product number	Packaging	Price	Buy
855642	25g	$83.3	Buy
855642	100g	$168	Buy
A0693	25g	$29	Buy
A0693	250g	$131	Buy
37359	50g	$33	Buy

N-Acetyl-L-glutamic acid Chemical Properties, Uses, Production

Chemical Properties

white crystalline powder

Uses

N-Acetyl-L-glutamic Acid is the N-Acetyl analogue of the non-essential amino acid, L-glutamic acid (G596960). N-Acetyl-L-glutamic Acid activates carbamoyl phosphate synthetase in the urea cycle.

Uses

Substrate for acetylglutamate kinase. Inhibitor of N-acetyl-L-glutamate synthetase

Uses

N-Acetyl-L-glutamic acid is used as pharmaceutical intermediates.

Definition

ChEBI: N-acetyl-L-glutamic acid is an N-acyl-L-amino acid that is L-glutamic acid in which one of the amine hydrogens is substituted by an acetyl group. It has a role as a Saccharomyces cerevisiae metabolite and a human metabolite. It is a N-acetyl-L-amino acid and a N-acyl-L-glutamic acid. It is functionally related to a L-glutamic acid. It is a conjugate acid of a N-acetyl-L-glutamate(1-).

reaction suitability

reaction type: solution phase peptide synthesis

Purification Methods

A likely impurity is glutamic acid. Crystallise it from boiling water. It inhibits N-acetyl-L-glutamate synthase. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1948 1961, Shigesada & Tatibana Eur J Biochem 84 285 1978, Coude Biochem Biophys Res Commun 102 1016 1981, Beilstein 4 IV 3047.]

N-Acetyl-L-glutamic acid synthesis

Synthesis of N-Acetyl-L-glutamic acid from L-Glutamic acid and Acetic anhydride

N-Acetyl-L-glutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

N-Acetyl-L-glutamic acid Suppliers

Global Suppliers ( 476)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Kaisai Chemical Co., Ltd	021-33516722 13701817765	kaisaichem@163.com	China	4604	58
Nanjing Yihua Biotechnology Co., Ltd	13429882898; 13429882898	1096323105@qq.com	China	291	58
Wuhan penglei Biotechnology Co., Ltd	15871464247 17307245989	3471278124@qq.com	China	4990	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Sichuan Tongsheng Amino acids Co.,Ltd.	0838-2274206 17340404235	sales@biots.cn	China	300	66
TAIYUAN RHF CO.,LTD.	+86 351 7031519	sales@RHFChem.com	China	2334	56
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing dtftchem Technology Co., Ltd.	010-60275820 13031183356	elainezt@sina.com	China	1386	62

Supplier	Advantage
Shanghai Kaisai Chemical Co., Ltd	58
Nanjing Yihua Biotechnology Co., Ltd	58
Wuhan penglei Biotechnology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Sichuan Tongsheng Amino acids Co.,Ltd.	66
TAIYUAN RHF CO.,LTD.	56
TCI (Shanghai) Development Co., Ltd.	81
Beijing dtftchem Technology Co., Ltd.	62

View Latest Price from N-Acetyl-L-glutamic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	N-Acetyl-L-glutamic acid 1188-37-0		1KG	98%min	1000kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-02	N-Acetyl-L-glutamic acid 1188-37-0	$5.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2026-06-02	N-Acetyl-L-glutamic acid 1188-37-0	$30.00		99.64%	10g	TargetMol Chemicals Inc.

N-Acetyl-L-glutamic acid
1188-37-0
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

N-Acetyl-L-glutamic acid
1188-37-0
$5.00
99%
Henan Fengda Chemical Co., Ltd

N-Acetyl-L-glutamic acid
1188-37-0
$30.00
99.64%
TargetMol Chemicals Inc.

N-Acetyl-L-glutamic acid Spectrum

N-Acetyl-L-glutamic acid(1188-37-0)MS N-Acetyl-L-glutamic acid(1188-37-0)¹HNMR N-Acetyl-L-glutamic acid(1188-37-0)¹³CNMR N-Acetyl-L-glutamic acid(1188-37-0)IR1 N-Acetyl-L-glutamic acid(1188-37-0)IR2 N-Acetyl-L-glutamic acid(1188-37-0)Raman

1188-37-0 (N-Acetyl-L-glutamic acid) Related Search:

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H-Ala-Glu-OH H-Lys-Glu-OH L-Glutamine

1of4

acetylglutamicacid L-Glutamic acid, N-acetyl- l-glutamicaci N-ALPHA-ACETYL-L-GLUTAMIC ACID N-AC-L-GLU N-ACETYL-L-GLU N-ACETYL-L-GLUTAMIC ACID ACETYL-L-GLUTAMIC ACID AC-GLU-OH L-2-ACETAMIDOGLUTARIC ACID N-ACETYL-L-GLUTAMIC ACID, AC-GLU-OH N-Acetyl-L-Glutamic N-Acetyl-L(DL)-Glutamic acid N-ACETYL-L-GLUTAMIC ACID USP (2S)-2-Acetamidopentanedioic acid N-Acetyl-S-glutamic acid NAcGlu N-Acetyl-L-glutamic acid,99% N-Acetyl-L-glutaic Acid N-Acetyl-L-glutaMic-d5 Acid N-ACETYL-L-GLUTAMIC ACID FOR SYNTHESIS (S)-2-acetaMidopentanedioic acid N-Ac-Glu-OH N-Ac-L-Glu-OH Acetyl-L-glutamic acid98-102% (Assay) Ac-L-Glu-OH N-acetyl-L-glutamate(2-) Repaglinide Impurity Q N-Acetyl-L-glutaMic acid ReagentPlus(R), 99% N-Acetyl-L-glutamic acid Vetec(TM) reagent grade, 99% l-n-acetylglutamicacid n-acetylglutamic n-acetyl-glutamicaci n-acetylglutamicacid n-acetyl-l-glutamicaci Repaglinide Impurity 13 Ac-L-Glutamic acid Repaglinide Impurity 7 N-Acetyl-L-glutamicAcid> Acetyl-L-glutamicaci N-Acetyl-L-glutamic acid USP/EP/BP N-Acetyl-L-Glutamic Acid extrapure, 99% N-Acetyl-L-glutamic acid, 10 mM in DMSO N cetyl-L-glutamic acid N-Acetyl-L-glutamic acid N-Acetyl-L-glutamate n-acetylglutamate N-Acetylglutamic acid 1188-37-0 C7H11NO5 HO2CCH2CH2CHNHCOCH3CO2H Peptide Synthesis Specialty Synthesis Amino Acid Derivatives Glutamic acid [Glu, E] Ac-Amino Acids Amino Acids Amino Acids (N-Protected)