Fenclorim
- CAS No.
- 3740-92-9
- Chemical Name:
- Fenclorim
- Synonyms
- 4,6-DICHLORO-2-PHENYLPYRIMIDINE;Soft;SOFIT;enclorim;femclorim;FENCLORIM;NSC 27713;fenclorime;cga-123407;fenchlorim
- CBNumber:
- CB6187251
- Molecular Formula:
- C10H6Cl2N2
- Molecular Weight:
- 225.07
- MDL Number:
- MFCD00754193
- MOL File:
- 3740-92-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Fenclorim PESTANAL | 46005 | 250mg | $83.8 |
| Fenclorim >98.0%(GC) | F0851 | 1g | $62 |
| Fenclorim >98.0%(GC) | F0851 | 5g | $208 |
| Fenclorim (4,6-dichloro-2-phenylpyrimidine) | F0045-95 | 5g | $403 |
| Fenclorim | TRC-F247500-250MG | 250mg | $103 |
| More product size | |||
| Melting point | 92-93°C |
|---|---|
| Boiling point | 235.5±33.0 °C(Predicted) |
| Density | 1.363±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly) |
| pka | -4.69±0.30(Predicted) |
| color | Off-White to Pale Yellow |
| Water Solubility | Insoluble in water |
| BRN | 142293 |
| Henry's Law Constant | 5.6×10-1 mol/(m3Pa) at 25℃, Ebert et al. (2023) |
| InChI | InChI=1S/C10H6Cl2N2/c11-8-6-9(12)14-10(13-8)7-4-2-1-3-5-7/h1-6H |
| InChIKey | NRFQZTCQAYEXEE-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=CC=C2)=NC(Cl)=CC(Cl)=N1 |
| CAS DataBase Reference | 3740-92-9(CAS DataBase Reference) |
| FDA UNII | 53665T9BHJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H332 | |||||||||
| Precautionary statements | P261-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20-43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UV8258400 | |||||||||
| HS Code | 2933.59.1000 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
Fenclorim price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46005 | Fenclorim PESTANAL | 3740-92-9 | 250mg | $83.8 | 2022-05-15 | Buy |
| TCI Chemical | F0851 | Fenclorim >98.0%(GC) | 3740-92-9 | 1g | $62 | 2026-04-30 | Buy |
| TCI Chemical | F0851 | Fenclorim >98.0%(GC) | 3740-92-9 | 5g | $208 | 2026-04-30 | Buy |
| Usbiological | F0045-95 | Fenclorim (4,6-dichloro-2-phenylpyrimidine) | 5g | $403 | 2026-06-03 | Buy | |
| TRC | TRC-F247500-250MG | Fenclorim | 3740-92-9 | 250mg | $103 | 2026-06-03 | Buy |
Fenclorim Chemical Properties,Uses,Production
Description
Fenclorim (4,6-dichloro-2-phenylpyrimidine) is a pyrimidine herbicide safener that effectively protects rice (Oryza sativa L.) from the phytotoxicity of certain herbicides. It improves rice tolerance to chloroacetanilide herbicides by enhancing the expression of detoxifying glutathione S-transferase (GST). Compared with seed treatment with safener alone, sequential seed treatment with safener and insecticide minimizes the release of fenclorim without causing residue problems in the ecosystem and harvested rice.
Chemical Properties
White to off-white solid
Uses
Herbicide safener.
Definition
ChEBI: Fenclorim is a member of pyrimidines and an organohalogen compound.
Synthesis
13566-71-7
3740-92-9
The general procedure for the synthesis of 4,6-dichloro-2-phenyl-pyrimidine from 2-phenylpyrimidine-4,6-diol was as follows: 300 ml of phosphoryl chloride was added to 40 g of 2-phenylpyrimidine-4,6-diol. The reaction mixture was heated to reflux at 100 °C for 48 hours. Upon completion of the reaction, the excess phosphoryl chloride was removed by distillation under reduced pressure (20 mbar). Subsequently, 200 ml of chloroform and 100 ml of ice water were added to the reaction mixture and stirred thoroughly for 30 minutes. The pH of the mixture was adjusted to 5-6 with aqueous sodium carbonate. the organic layer was separated and the aqueous phase was extracted three times with 200 mL of chloroform. All chloroform phases were combined, dried with magnesium sulfate, filtered and the chloroform was removed by evaporation under reduced pressure. The resulting crude product can be purified by distillation under reduced pressure or by column chromatography using 60 mesh silica gel (with chloroform as eluent).
References
[1] Patent: US2003/162764, 2003, A1
[2] Bulletin of the Korean Chemical Society, 2012, vol. 33, # 8, p. 2627 - 2634
[3] Patent: US6372751, 2002, B1. Location in patent: Example Pr3
[4] Australian Journal of Chemistry, 2015, vol. 68, # 5, p. 814 - 824
[5] Farmaco, 1997, vol. 52, # 1, p. 61 - 65
Fenclorim Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huizhili (Changzhou) Life Technology Co., Ltd | 13906110102 | 13906110102@139.com | China | 16 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3961 | 58 |
| Qingdao Trust Agri Chemical Co.,Ltd | +86-008615963231493 +86-008613573296305 | trustagri@hotmail.com | China | 298 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9628 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9036 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
View Lastest Price from Fenclorim manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Fenclorim
3740-92-9
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2025-12-25 | fenclorim
3740-92-9
|
1kg | 99% | Huizhili (Changzhou) Life Technology Co., Ltd | |||
 |
2024-10-22 | Fenclorim
3740-92-9
|
$1.00 | 1g | 98% | 1g/10kg/100kg | Career Henan Chemica Co |
