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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile structure

CAS No.: 330792-70-6

Chemical Name:: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Synonyms: 3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile;IbrutinibN-3;IbrutinibIntermediate4;Ibrutinib intermediate3;Zanubrutinib Impurity 8;Zanubrutinib impurity-20;Ibrutinib intermediates N-3;Zanubrutinib Related Compound 6;3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole;3-amino-4-cyano group-5-(4-Phenoxyphenyl)Pyrazole

CBNumber:: CB62604963

Molecular Formula:: C16H12N4O

Molecular Weight:: 276.29

MDL Number:: MFCD20270361

MOL File:: 330792-70-6.mol

MSDS File:: SDS

Last updated:2026-05-28 04:36:38

Product description	Number	Pack Size	Price
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	A23083	100mg	$15
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	A23083	250mg	$19
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	A23083	1g	$21
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	A23083	5g	$26
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	A23083	10g	$50
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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Properties

Boiling point	585.3±50.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
refractive index	1.699
Flash point	307.8℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly)
pka	10.83±0.50(Predicted)
Appearance	Off-white to light yellow Solid
InChI	InChI=1S/C16H12N4O/c17-10-14-15(19-20-16(14)18)11-6-8-13(9-7-11)21-12-4-2-1-3-5-12/h1-9H,(H3,18,19,20)
InChIKey	HNIMEQCLCNSCGH-UHFFFAOYSA-N
SMILES	N1C(C2=CC=C(OC3=CC=CC=C3)C=C2)=C(C#N)C(N)=N1
LogP	3.25298

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
REACH Registrations	Active

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	A23083	3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	330792-70-6	100mg	$15	2026-05-06	Buy
Synthonix	A23083	3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	330792-70-6	250mg	$19	2026-05-06	Buy
Synthonix	A23083	3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	330792-70-6	1g	$21	2026-05-06	Buy
Synthonix	A23083	3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	330792-70-6	5g	$26	2026-05-06	Buy
Synthonix	A23083	3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile 97%	330792-70-6	10g	$50	2026-05-06	Buy

Product number	Packaging	Price	Buy
A23083	100mg	$15	Buy
A23083	250mg	$19	Buy
A23083	1g	$21	Buy
A23083	5g	$26	Buy
A23083	10g	$50	Buy

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties,Uses,Production

Chemical Properties

Light yellow to off-white powder.

Uses

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck)

Application

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765). it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor.

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile synthesis

Synthesis of 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile from Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]-

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials

Raw materials

4-PHENOXYBENZOYL CHLORIDE Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Methyl 4-iodobenzoate 4-PHENOXYBENZOIC ACID

4-Phenoxybenzoic acid methyl ester Phenol Malononitrile

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Preparation Products

3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NANJING YINGWEN BIOTECHNOLOGY CO LTD	+8613382787392	sales@aeechem.com	China	10001	58
SyncoZymes (Shanghai) Co., Ltd.,	+8613681683526	lchen@syncozymes.com	China	286	58
Jinan Dexinjia Bio&Tech Co., Ltd	+86-0531-82375818 +86-15064153060	sales@jndxj.com	China	1285	58
Jinan Jianfeng Chemical Co., Ltd	+86-0531-88110457 +8615562555968	info@pharmachemm.com	China	310	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58

Supplier	Advantage
NANJING YINGWEN BIOTECHNOLOGY CO LTD	58
SyncoZymes (Shanghai) Co., Ltd.,	58
Jinan Dexinjia Bio&Tech Co., Ltd	58
Jinan Jianfeng Chemical Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58

View Lastest Price from 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6	$3.00-10.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2025-08-29	5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6		1kg	99%	1	Jinan Ruitong Biotech Co., Ltd.

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
98.0%
Shaanxi Dideu New Materials Co. Ltd

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
$3.00-10.00
99%
Henan Fengda Chemical Co., Ltd

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
330792-70-6
99%
Jinan Ruitong Biotech Co., Ltd.

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Spectrum

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile(330792-70-6)¹HNMR

330792-70-6(5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile)Related Search:

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(1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate ent-Tadalafil cis-ent-Tadalafil cis-Tadalafil (S)-1-Boc-3-hydroxypiperidine

Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Chloropretadalafil Trelagliptin succinate Tadalafil (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine (R)-1-Boc-3-Hydroxypiperidine

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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole 1H-Pyrazole-4-carbonitrile, 3-aMino-5-(4-phenoxyphenyl)- 3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile Ibrutinib intermediates N-3 Zanubrutinib Related Compound 6 Zanubrutinib Impurity 8 Ibrutinib intermediate3 IbrutinibN-3 CAS330792-70-6 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Zanubrutinib KSM-II : (4-isocyano-3-(4-phenoxyphenyl)-1H-pyrazol-5-amine) IbrutinibIntermediate4 Zanubrutinib impurity-20 Zanubrutinib impurity-8 (3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole 3-amino-4-cyano group-5-(4-Phenoxyphenyl)Pyrazole 3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile 330792-70-6 330790-70-6 330792-70-6