2-Chloro-6-methylnicotinic acid
- CAS No.
- 30529-70-5
- Chemical Name:
- 2-Chloro-6-methylnicotinic acid
- Synonyms
- 4-Chloro-6-methylnicotinic acid;3-Pyridinecarboxylic acid, 2-chloro-6-methyl-;TIMTEC-BB SBB003843;RARECHEM AL BO 0683;2-CHLORO-6-METHYLNICOTINIC ACID;6-METHYL-2-CHLORO NICOTINIC ACID;2-Chlroro-6-Methylnicotinic Acid;2-Chloro-6-methylnicotinicacid,97%;2-Chloro-6-methylnicotinic acid 98%;3-CARBOXY-2-CHLORO-6-METHYLPYRIDINE
- CBNumber:
- CB6267128
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MDL Number:
- MFCD00134165
- MOL File:
- 30529-70-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-6-methylpyridine-3-carboxylic acid 97% | 357847 | 5g | $94.5 |
| 2-Chloro-6-methylnicotinic Acid >98.0%(GC)(T) | C1762 | 5g | $98 |
| 2-Chloro-6-methylnicotinic Acid >98.0%(GC)(T) | C1762 | 25g | $390 |
| 2-CHLORO-6-METHYLNICOTINICACID 97% | CL0085 | 25G | $77 |
| 2-Chloro-6-methylnicotinic acid | FC09440 | 10g | $150 |
| More product size | |||
| Melting point | 162-164 °C (lit.) |
|---|---|
| Boiling point | 163 °C / 22mmHg |
| Density | 1.3246 (rough estimate) |
| refractive index | 1.5560 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | Crystalline Powder |
| pka | 2.28±0.28(Predicted) |
| color | White to yellow to beige |
| BRN | 473070 |
| InChI | InChI=1S/C7H6ClNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H,10,11) |
| InChIKey | ACQXHCHKMFYDPM-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(C)=CC=C1C(O)=O |
| CAS DataBase Reference | 30529-70-5(CAS DataBase Reference) |
| FDA UNII | 6HJ6V3KP7Q |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P304+P340-P405-P501a-P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Chloro-6-methylnicotinic acid price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 357847 | 2-Chloro-6-methylpyridine-3-carboxylic acid 97% | 30529-70-5 | 5g | $94.5 | 2022-05-15 | Buy |
| TCI Chemical | C1762 | 2-Chloro-6-methylnicotinic Acid >98.0%(GC)(T) | 30529-70-5 | 5g | $98 | 2026-04-30 | Buy |
| TCI Chemical | C1762 | 2-Chloro-6-methylnicotinic Acid >98.0%(GC)(T) | 30529-70-5 | 25g | $390 | 2026-04-30 | Buy |
| AstaTech | CL0085 | 2-CHLORO-6-METHYLNICOTINICACID 97% | 30529-70-5 | 25G | $77 | 2026-04-30 | Buy |
| Biosynth | FC09440 | 2-Chloro-6-methylnicotinic acid | 30529-70-5 | 10g | $150 | 2026-06-04 | Buy |
2-Chloro-6-methylnicotinic acid Chemical Properties,Uses,Production
Chemical Properties
white to yellow crystalline powder
Uses
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.
General Description
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) is a nicotinic acid derivative.
Synthesis
28900-10-9
30529-70-5
General procedure for the synthesis of 2-chloro-6-methylnicotinic acid from 2-chloro-6-methyl-3-pyridinecarbonitrile: First, 2-chloro-3-cyano-6-methylpyridine (3.05 g) was dissolved in 75% sulfuric acid (10 mL). The reaction mixture was stirred at 110 °C for 2 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature and slowly added dropwise to ice water. After stirring the ice-water mixture for 10 minutes, the precipitated crystals were collected by filtration and dried to give 2.91 g of 2-chloro-6-methylnicotinic acid in 85% yield. Next, the resulting 2-chloro-6-methylnicotinic acid (2.91 g) was mixed with 28% aqueous ammonia solution (35 mL) and placed in an autoclave and reacted at 170 °C for 40 hours. At the end of the reaction, the reaction solution was cooled to room temperature and the ammonia was removed by distillation under reduced pressure. The precipitated crystals were collected by filtration, washed with water and air-dried to give 1.91 g of amino-6-methylnicotinic acid in 74% yield. The total yield of the whole synthesis process was 62.9%.
References
[1] Patent: TW2016/509, 2016, A. Location in patent: Page/Page column 6
2-Chloro-6-methylnicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongle Biotechnology Co., Ltd | +86-13472573725 | sales@yichangchemcial.com | China | 300 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5898 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
View Lastest Price from 2-Chloro-6-methylnicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 2-Chloro-6-methylnicotinic acid
30529-70-5
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2021-07-02 | 2-Chloro-6-methylnicotinic acid
30529-70-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 2-Chloro-6-methylnicotinic acid
30529-70-5
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2-Chloro-6-methylnicotinic acid
30529-70-5
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Chloro-6-methylnicotinic acid
30529-70-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-Chloro-6-methylnicotinic acid
30529-70-5
- $1.00
- 99%
- Career Henan Chemical Co
