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1-Bromo-3-ethynyl-benzene

1-Bromo-3-ethynyl-benzene Structure
1-Bromo-3-ethynyl-benzene structure
CAS No.
766-81-4
Chemical Name:
1-Bromo-3-ethynyl-benzene
Synonyms
3-BROMOPHENYLACETYLENE;3'-BROMOPHENYL ACETYLENE;1-Bromo-3-ethynyl-benzene;Benzene, 1-broMo-3-ethynyl-;3-Bromophenylacetylene - [B47527]
CBNumber:
CB6297455
Molecular Formula:
C8H5Br
Molecular Weight:
181.03
MDL Number:
MFCD03839983
MOL File:
766-81-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:11
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1-Bromo-3-ethynyl-benzene Properties

Boiling point 198.24°C (rough estimate)
Density 1.4466
refractive index 1.5896
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
Appearance Colorless to light yellow Liquid
InChI InChI=1S/C8H5Br/c1-2-7-4-3-5-8(9)6-7/h1,3-6H
InChIKey TZDXNFAAJNEYIO-UHFFFAOYSA-N
SMILES C1(Br)=CC=CC(C#C)=C1
CAS DataBase Reference 766-81-4(CAS DataBase Reference)
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39
WGK Germany  WGK 3
HS Code  2903998090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

1-Bromo-3-ethynyl-benzene price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS007533 3′-bromophenyl acetylene AldrichCPR 500 mg $197 2026-04-30 Buy
TCI Chemical B5198 1-Bromo-3-ethynylbenzene min. 98.0 % 766-81-4 1G $127 2026-04-30 Buy
TCI Chemical B5198 1-Bromo-3-ethynylbenzene min. 98.0 % 766-81-4 5G $380 2026-04-30 Buy
AstaTech 96933 3'-BROMOPHENYL ACETYLENE 97% 766-81-4 1G $28 2026-04-30 Buy
AstaTech 96933 3'-BROMOPHENYL ACETYLENE 97% 766-81-4 5G $118 2026-04-30 Buy
Product number Packaging Price Buy
CDS007533 500 mg $197 Buy
B5198 1G $127 Buy
B5198 5G $380 Buy
96933 1G $28 Buy
96933 5G $118 Buy

1-Bromo-3-ethynyl-benzene Chemical Properties, Uses, Production

Synthesis

(3-BROMOPHENYLETHYNYL)TRIMETHYLSILANE

3989-13-7

1-BROMO-3-ETHYNYL-BENZENE

766-81-4

The general procedure for the synthesis of 3'-bromophenylacetylene from (3-bromophenylethynyl)trimethylsilane was as follows: intermediate 1-1 (166 g, 655.6 mmol) was dissolved in methanol (1000 mL) and placed in the reactor. Subsequently, potassium carbonate (90.6 g, 655.6 mmol) was added slowly and dropwise to the above solution. The reaction mixture was stirred at room temperature for about 30 minutes and then filtered. The filtrate was distilled under reduced pressure to remove the solvent and the residue was dissolved in ethyl acetate. This ethyl acetate solution was washed twice with distilled water to remove water soluble impurities. Finally, the organic solvent was removed by reduced pressure distillation to give intermediates 1-2 (116 g, 98% yield).

References

[1] Patent: US2018/339967, 2018, A1. Location in patent: Paragraph 0159; 0161
[2] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 630 - 639
[3] European Journal of Organic Chemistry, 2010, # 33, p. 6323 - 6330
[4] Organic Letters, 2017, vol. 19, # 19, p. 5182 - 5185
[5] Patent: US2009/48320, 2009, A1. Location in patent: Page/Page column 62; 82

1-Bromo-3-ethynyl-benzene synthesis

2142-63-4
766-81-4
138857-35-9
Synthesis of 1-Bromo-3-ethynyl-benzene from 3'-Bromoacetophenone

1-Bromo-3-ethynyl-benzene Preparation Products And Raw materials

Raw materials

POWMKQRQDNARSN-UHFFFAOYSA-N (3-Bromophenylethynyl)trimethylsilane 3-Bromocinnamic acid 1-Bromo-3-iodobenzene Methanol
Dimethyl (1-Diazo-2-oxopropyl)phosphonate 3-Bromobenzaldehyde Trimethylsilylacetylene 3'-Bromoacetophenone

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Preparation Products

3-Bromo-alpha-methylbenzyl alcohol 1,3,5-Tris(3-bromophenyl)benzene 3-Bromophenacyl bromide 2-Propynoic acid, 3-(3-bromophenyl)-, ethyl ester

1-Bromo-3-ethynyl-benzene Suppliers

Global Suppliers ( 155)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Supplier Advantage
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Accela ChemBio Co.,Ltd. 64
Shanghai Longsheng chemical Co.,Ltd. 59
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Sichuan Kulinan Technology Co., Ltd 57

View Latest Price from 1-Bromo-3-ethynyl-benzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3'-Bromophenyl acetylene pictures 2026-08-25 3'-Bromophenyl acetylene
766-81-4
 $2.20-8.80 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
1-BROMO-3-ETHYNYL-BENZENE pictures 2023-11-15 1-BROMO-3-ETHYNYL-BENZENE
766-81-4
 1kg 99.9% 30000 Kg Hebei Xinsheng New Material Technology Co., LTD.
1-BROMO-3-ETHYNYL-BENZENE pictures 2023-11-07 1-BROMO-3-ETHYNYL-BENZENE
766-81-4
 $25.00-35.00 1kg 99% 20 Ton Hebei Xinsheng New Material Technology Co., LTD.

1-Bromo-3-ethynyl-benzene Spectrum

1-BROMO-3-ETHYNYL-BENZENE(766-81-4)1HNMR

766-81-4 (1-Bromo-3-ethynyl-benzene) Related Search:

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4-(3-Bromophenyl)-2-methyl-3-butyn-2-ol 1-Bromo-3-ethynyl-benzene 3-Bromo-1-ethynyl-6-methoxy-benzene 4-Bromo-2-ethynyl-6-methoxy-phenol 2,4-Dibromo-6-ethynyl-phenylamine
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4-Bromophenylacetylene

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3'-BROMOPHENYL ACETYLENE 3-BROMOPHENYLACETYLENE Benzene, 1-broMo-3-ethynyl- 3-Bromophenylacetylene - [B47527] 1-Bromo-3-ethynyl-benzene 766-81-4 Aromatic Halides (substituted)