Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- CAS No.
- 90965-06-3
- Chemical Name:
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- Synonyms
- DIMETHYL (1-DIAZO-2-OXOPROPYL)PHOSPHONATE;Bestmann-Ohira reagent;Ohira-Bestmann reagent;Bestmann-Ohira;1-Diazo-1-dimethoxyphosphoryl-propan-2-one;Dimethyl (acetyldiazomethyl)phosphonate;Dimethyl (1-Diazo-2-oxopropyl)phosphonat;dimethyl 1-(1-diazo-2-oxopropyl)phosphonate;1-Diazoacetonylphosphonic Acid Dimethyl Ester;(1-DIAZO-2-OXO-PROPYL)-PHOSPHONIC ACID DIMETHYL ESTER
- CBNumber:
- CB8489377
- Molecular Formula:
- C5H9N2O4P
- Molecular Weight:
- 192.11
- MDL Number:
- MFCD07368360
- MOL File:
- 90965-06-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.28 |
|---|---|
| refractive index | n20/D1.352-1.354 |
| Flash point | 2℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol (Slightly) |
| form | Oil |
| color | Pale Yellow to Yellow |
| Merck | 14,1177 |
| BRN | 4247670 |
| Stability | Light Sensitive |
| InChI | InChI=1S/C5H9N2O4P/c1-4(8)5(7-6)12(9,10-2)11-3/h1-3H3 |
| InChIKey | SQHSJJGGWYIFCD-UHFFFAOYSA-N |
| SMILES | P(=O)(OC)(OC)C(=[N+]=[N-])C(=O)C |
| FDA UNII | 96G79J0LR6 |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302+H312+H332-H319 | |||||||||
| Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | F,Xn | |||||||||
| Risk Statements | 11-20/21/22-36 | |||||||||
| Safety Statements | 16-26-36/37 | |||||||||
| RIDADR | UN 1648 3 / PGII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Flam. Liq. 2 |
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| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
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Dimethyl (1-Diazo-2-oxopropyl)phosphonate price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 742724 | Dimethyl (1-diazo-2-oxopropyl)phosphonate solution ~10% in acetonitrile (H-NMR), ≥96% (HPLC) | 90965-06-3 | 10ml | $535 | 2026-04-30 | Buy |
| TCI Chemical | D3546 | Dimethyl (1-Diazo-2-oxopropyl)phosphonate >97.0%(HPLC) | 90965-06-3 | 1g | $125 | 2026-04-30 | Buy |
| TCI Chemical | D3546 | Dimethyl (1-Diazo-2-oxopropyl)phosphonate >97.0%(HPLC) | 90965-06-3 | 5g | $445 | 2026-04-30 | Buy |
| TRC | TRC-D471815-250MG | Dimethyl (1-Diazo-2-oxopropyl)phosphonate | 90965-06-3 | 250mg | $103 | 2026-06-03 | Buy |
| TRC | TRC-D471815-2.5G | Dimethyl (1-Diazo-2-oxopropyl)phosphonate | 90965-06-3 | 2.5g | $320 | 2026-06-03 | Buy |
Dimethyl (1-Diazo-2-oxopropyl)phosphonate Chemical Properties,Uses,Production
Description
Dimethyl (1-diazido-2-oxopropyl)phosphonate is a liquid-added organophosphorus flame retardant with good solubility with water, common organic solvents, and inorganic salts flame retardants, with excellent flame retardant properties, low price and low additive amount and other advantages.
Chemical Properties
Light yellow liquid
Uses
Reagent for transformation of aldehydes to terminal alkynes and ketones to methyl enol ethers.
Application
Dimethyl (1-diazo-2-oxopropyl)phosphonate can be used as a reagent for the synthesis of:
Ethynyl compounds (alkynes) from aldehydes.
Isoquinoline and pyridine N-oxides by cyclization with oximes in the presence of Rh catalyst.
Dimethyl(diazomethyl)phosphonate through methanolysis, which is further employed as a reagent in the synthesis of enol ethers or alkynes.
Five-member heterocyclic scaffolds of pyrazoles, triazoles, and oxazoles via cycloaddition reaction and multicomponent reaction.
reaction suitability
reaction type: C-C Bond Formation
Synthesis
Dissolve NaH (0.67 g, 60% w/w, 16.75 mmol) in benzene (45 mL) and dry THF (15 mL). Cool the mixture on ice. A solution of dimethyl (2-oxopropyl) phosphonate (15.3 mmol) in dry benzene (15 mL) was added. A white solid was formed. The reaction mixture was stirred at room temperature for 1 hour. To the mixture was added a solution of toluidic acid hydrazide (16.23 mmol) in dry benzene (7.5 mL). The mixture was stirred at room temperature overnight. The mixture was filtered with Hyflo. The mixture was concentrated in a vacuum to give dimethyl (1-diazido-2-oxopropyl)phosphonate.
Dimethyl (1-Diazo-2-oxopropyl)phosphonate Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| skychemical Co.Ltd | 021-20960837,QQ1332204249 | sales@skychemical.com | China | 3338 | 55 |
| Tianjin YongSheng Biotechnology Co., Ltd. | 022-60987737 13512258274;13820956092 | sales@immortalbio.com | China | 154 | 55 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shaoxing Hengchuang Heyi Biotechnology Co., Ltd | 15158234258 | 3991135489@qq.com | China | 324 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Lastest Price from Dimethyl (1-Diazo-2-oxopropyl)phosphonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Dimethyl (1-diazo-2-oxopropyl)phosphonate
90965-06-3
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | (1-DIAZO-2-OXO-PROPYL)-PHOSPHONIC ACID DIMETHYL ESTER
90965-06-3
|
$1.00 | 1kg | as customer's need | 1000kg | Career Henan Chemical Co |
-
- Dimethyl (1-diazo-2-oxopropyl)phosphonate
90965-06-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- (1-DIAZO-2-OXO-PROPYL)-PHOSPHONIC ACID DIMETHYL ESTER
90965-06-3
- $1.00
- as customer's need
- Career Henan Chemical Co
