2,4-Dichloro-6-methyl-5-nitropyrimidine
- CAS No.
- 13162-26-0
- Chemical Name:
- 2,4-Dichloro-6-methyl-5-nitropyrimidine
- Synonyms
- 2,4-Dic;NSC 122005;2,4-Dichloro-6-Methyl-5-Nitro;Methyl 2,6-Dichloro-5-nitropyriMidine;2,4-dichlor-6-methyl-5-nitropyrimidin;4-Dichloro-6-Methyl-5-nitro-pyriMidine;2,4-dichloro-6-methyl-5-nitropyrimidin;2,6-DICHLORO-4-METHYL-5-NITROPYRIMIDINE;2,4-DICHLORO-5-NITRO-6-METHYLPYRIMIDINE;2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE
- CBNumber:
- CB6320858
- Molecular Formula:
- C5H3Cl2N3O2
- Molecular Weight:
- 208
- MDL Number:
- MFCD00023196
- MOL File:
- 13162-26-0.mol
- MSDS File:
- SDS
| Melting point | 52-54°C |
|---|---|
| Boiling point | 135-136 °C(Press: 22 Torr) |
| Density | 1.626±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | -5.30±0.39(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Beige |
| Stability | Moisture Sensitive |
| InChI | InChI=1S/C5H3Cl2N3O2/c1-2-3(10(11)12)4(6)9-5(7)8-2/h1H3 |
| InChIKey | NBCOZXBHPKSFSA-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(C)=C([N+]([O-])=O)C(Cl)=N1 |
| CAS DataBase Reference | 13162-26-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-41-36/37/38 |
| Safety Statements | 26-39-36/37/39 |
| HS Code | 29335990 |
2,4-Dichloro-6-methyl-5-nitropyrimidine price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | D3531-25 | 2,4-Dichloro-6-methyl-5-nitropyrimidine | 13162-26-0 | 5g | $319 | 2026-06-03 | Buy |
| TRC | TRC-D435450-5G | 2,4-Dichloro-6-methyl-5-nitropyrimidine | 13162-26-0 | 5g | $65 | 2026-06-03 | Buy |
| TRC | TRC-D435450-25G | 2,4-Dichloro-6-methyl-5-nitropyrimidine | 13162-26-0 | 25g | $193 | 2026-06-03 | Buy |
| TRC | TRC-D435450-10G | 2,4-Dichloro-6-methyl-5-nitropyrimidine | 13162-26-0 | 10g | $103 | 2026-06-03 | Buy |
| AstaTech | 60466 | 2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 95% | 13162-26-0 | 5G | $31 | 2026-04-30 | Buy |
2,4-Dichloro-6-methyl-5-nitropyrimidine Chemical Properties, Uses, Production
Chemical Properties
Yellow Crystalline Solid
Uses
A synthetic intermediate
Synthesis
16632-21-6
13162-26-0
General procedure for the synthesis of 2,4-dichloro-5-nitro-6-methylpyrimidine from 2,4-dihydroxy-6-methyl-5-nitropyrimidine: 2,4-dihydroxy-6-methyl-5-nitropyrimidine (1 eq.) was dissolved in 17.54 mL of phosphoryl chloride, and 2.92 mL of N,N-dimethylaniline (1 eq.) was slowly added dropwise at room temperature. Subsequently, 8.04 μL of DMF (0.00445 eq.) was slowly added under reflux conditions and the reaction lasted for 8 hours. Upon completion of the reaction, the trichlorophosphorus oxide was removed by distillation under reduced pressure. Ice water was added to the residue and extracted with ethyl acetate. The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by rotary evaporation to give a light yellow to brown oil. The oily substance was purified by column chromatographic separation to give a final yellow solid 2,4-dichloro-5-nitro-6-methylpyrimidine (1 g) in 65% yield.
References
[1] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0031
[2] Bulletin de la Societe Chimique de France, 1951, p. 428
[3] Helvetica Chimica Acta, 1951, vol. 34, p. 835,837
[4] Journal of the Chemical Society, 1951, p. 1004,1015
[5] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, vol. 24, p. 84
2,4-Dichloro-6-methyl-5-nitropyrimidine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Standard Chemicals Ltd. | 0519-85607885 13776800733 | email@standardschem.com | China | 118 | 62 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from 2,4-Dichloro-6-methyl-5-nitropyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-05-18 | 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd | |||
 |
2023-06-19 | 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
|
1kg | 98% | Capot Chemical Co.,Ltd. |
-
- 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
- 98%
- Capot Chemical Co.,Ltd.
