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2,4-Dichloro-6-methyl-5-nitropyrimidine

2,4-Dichloro-6-methyl-5-nitropyrimidine structure

CAS No.: 13162-26-0

Chemical Name:: 2,4-Dichloro-6-methyl-5-nitropyrimidine

Synonyms: 2,4-Dic;NSC 122005;2,4-Dichloro-6-Methyl-5-Nitro;Methyl 2,6-Dichloro-5-nitropyriMidine;2,4-dichlor-6-methyl-5-nitropyrimidin;4-Dichloro-6-Methyl-5-nitro-pyriMidine;2,4-dichloro-6-methyl-5-nitropyrimidin;2,6-DICHLORO-4-METHYL-5-NITROPYRIMIDINE;2,4-DICHLORO-5-NITRO-6-METHYLPYRIMIDINE;2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE

CBNumber:: CB6320858

Molecular Formula:: C5H3Cl2N3O2

Molecular Weight:: 208

MDL Number:: MFCD00023196

MOL File:: 13162-26-0.mol

MSDS File:: SDS

Last updated:2025-10-28 16:00:23

Product description	Number	Pack Size	Price
2,4-Dichloro-6-methyl-5-nitropyrimidine	D435450	25g	$150
2,4-Dichloro-6-methyl-5-nitropyrimidine	D3531-25	5g	$333
2,4-Dichloro-5-nitro-6-methylpyrimidine	ND70435	250g	$340
2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 95.00%	HCH0017657	1G	$410
2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 95.00%	HCH0017657	2.5G	$425
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2,4-Dichloro-6-methyl-5-nitropyrimidine Properties

Melting point	52-54°C
Boiling point	135-136 °C(Press: 22 Torr)
Density	1.626±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	-5.30±0.39(Predicted)
color	Pale Yellow to Light Beige
Stability	Moisture Sensitive
InChI	InChI=1S/C5H3Cl2N3O2/c1-2-3(10(11)12)4(6)9-5(7)8-2/h1H3
InChIKey	NBCOZXBHPKSFSA-UHFFFAOYSA-N
SMILES	C1(Cl)=NC(C)=C([N+]([O-])=O)C(Cl)=N1
CAS DataBase Reference	13162-26-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
Hazard Codes	Xi,Xn
Risk Statements	22-41-36/37/38
Safety Statements	26-39-36/37/39
HS Code	29335990

2,4-Dichloro-6-methyl-5-nitropyrimidine price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D435450	2,4-Dichloro-6-methyl-5-nitropyrimidine	13162-26-0	25g	$150	2021-12-16	Buy
Usbiological	D3531-25	2,4-Dichloro-6-methyl-5-nitropyrimidine	13162-26-0	5g	$333	2021-12-16	Buy
Biosynth Carbosynth	ND70435	2,4-Dichloro-5-nitro-6-methylpyrimidine	13162-26-0	250g	$340	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0017657	2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 95.00%	13162-26-0	1G	$410	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0017657	2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 95.00%	13162-26-0	2.5G	$425	2021-12-16	Buy

Product number	Packaging	Price	Buy
D435450	25g	$150	Buy
D3531-25	5g	$333	Buy
ND70435	250g	$340	Buy
HCH0017657	1G	$410	Buy
HCH0017657	2.5G	$425	Buy

2,4-Dichloro-6-methyl-5-nitropyrimidine Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

A synthetic intermediate

Synthesis

16632-21-6

13162-26-0

General procedure for the synthesis of 2,4-dichloro-5-nitro-6-methylpyrimidine from 2,4-dihydroxy-6-methyl-5-nitropyrimidine: 2,4-dihydroxy-6-methyl-5-nitropyrimidine (1 eq.) was dissolved in 17.54 mL of phosphoryl chloride, and 2.92 mL of N,N-dimethylaniline (1 eq.) was slowly added dropwise at room temperature. Subsequently, 8.04 μL of DMF (0.00445 eq.) was slowly added under reflux conditions and the reaction lasted for 8 hours. Upon completion of the reaction, the trichlorophosphorus oxide was removed by distillation under reduced pressure. Ice water was added to the residue and extracted with ethyl acetate. The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by rotary evaporation to give a light yellow to brown oil. The oily substance was purified by column chromatographic separation to give a final yellow solid 2,4-dichloro-5-nitro-6-methylpyrimidine (1 g) in 65% yield.

References

[1] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0031
[2] Bulletin de la Societe Chimique de France, 1951, p. 428
[3] Helvetica Chimica Acta, 1951, vol. 34, p. 835,837
[4] Journal of the Chemical Society, 1951, p. 1004,1015
[5] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, vol. 24, p. 84

2,4-Dichloro-6-methyl-5-nitropyrimidine synthesis

Synthesis of 2,4-Dichloro-6-methyl-5-nitropyrimidine from 5-Nitro-6-methyluracil

2,4-Dichloro-6-methyl-5-nitropyrimidine Preparation Products And Raw materials

Raw materials

6-Methyluracil Phosphorus oxitrichloride Diethyl ether Sodium bicarbonate Nitric acid

N,N-Diethylaniline Phosphorus pentoxide 5-Nitro-6-methyluracil N,N-Dimethylformamide N,N-Dimethylaniline

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Preparation Products

1H-Pyrazolo[4,3-d]pyriMidine, 5-chloro- 2-Chloro-6-methylpyrimidine-4,5-diamine

2,4-Dichloro-6-methyl-5-nitropyrimidine Suppliers

Global( 257)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Hefei Lbao Physical & Chemical Science Co.,Ltd	+1-5184799099	lbaochemicals@gmail.com	China	674	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 2,4-Dichloro-6-methyl-5-nitropyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-28	2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2025-11-18	2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2023-06-19	2,4-Dichloro-6-methyl-5-nitropyrimidine 13162-26-0	US $0.00-0.00 / kg	1kg	98%	Up to kgs	Capot Chemical Co.,Ltd.

2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
US $1.10 / g
99.00%
Dideu Industries Group Limited

2,4-Dichloro-6-methyl-5-nitropyrimidine
13162-26-0
US $0.00-0.00 / kg
98%
Capot Chemical Co.,Ltd.

2,4-Dichloro-6-methyl-5-nitropyrimidine Spectrum

2,4-Dichloro-6-methyl-5-nitropyrimidine(13162-26-0)¹HNMR

13162-26-0(2,4-Dichloro-6-methyl-5-nitropyrimidine)Related Search:

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2,4-DICHLORO-6-METHYL-5-NITROPYRIMIDINE 2,4-DICHLORO-5-NITRO-6-METHYLPYRIMIDINE 2,6-DICHLORO-4-METHYL-5-NITROPYRIMIDINE 2,4-Dichloro-6-Methyl-5-Nitro Pyrimidine, 2,4-dichloro-6-methyl-5-nitro- 2,4-Dichloro-6-methyl-5-nitropyrimidine ,98% 2,4-dichloro-6-methyl-5-nitropyrimidin 4-Dichloro-6-Methyl-5-nitro-pyriMidine Methyl 2,6-Dichloro-5-nitropyriMidine NSC 122005 2,4-Dic 2,4-Dichloro-6-methyl-5-nitropyrimidine ISO 9001：2015 REACH 2,4-dichlor-6-methyl-5-nitropyrimidin 13162-26-0 13126-26-0 162-26-0 C5H4Cl2N3O2 C5H3Cl2N3O2 C5H3C12N3O2 Heterocycle-Pyrimidine series Bases & Related Reagents Nucleotides Pyrimidine Series Nucleotides and Nucleosides Pyrimidines APIs & Intermediate Pyrimidine Pyridines, Pyrimidines, Purines and Pteredines