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1-(3-Chlorphenyl)piperazine

1-(3-Chlorphenyl)piperazine Structure
1-(3-Chlorphenyl)piperazine structure
CAS No.
6640-24-0
Chemical Name:
1-(3-Chlorphenyl)piperazine
Synonyms
MCPP;1-(3-CHLOROPHENYL)PIPERAZINE;CHLOROPHENYLPIPERAZINE;m-Chlorophenylpiperazine;NSC 49307;AKOS BBS-00003580;TIMTEC-BB SBB003579;RARECHEM AH CK 0071;1,3ChlorofenylPiperazine;3-chlorophenyl piperazine
CBNumber:
CB6325545
Molecular Formula:
C10H13ClN2
Molecular Weight:
196.68
MDL Number:
MFCD00040732
MOL File:
6640-24-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:21:28
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1-(3-Chlorphenyl)piperazine Properties

Melting point 210-214°C
Boiling point 105 °C
Density 1.193
refractive index 1,598-1,600
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Methanol (Sparingly)
form Oil
pka 8.85±0.10(Predicted)
color Colourless to Orange
LogP 2.468
CAS DataBase Reference 6640-24-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII REY0CNO998

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Hazard statements  H411
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-36
HazardClass  IRRITANT
HS Code  29339900
REACH Registrations Active

1-(3-Chlorphenyl)piperazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 006596 1-(3-Chlorophenyl)piperazine 6640-24-0 250mg $509 2026-06-03 Buy
TRC C379590 1-(3-Chlorophenyl)piperazine 6640-24-0 1g $240 2021-12-16 Buy
Frontier Specialty Chemicals JK287024 1-(3-Chlorophenyl)piperazine 98% 6640-24-0 5g $59 2021-12-16 Buy
Frontier Specialty Chemicals JK287024 1-(3-Chlorophenyl)piperazine 98% 6640-24-0 25g $219 2021-12-16 Buy
Medical Isotopes, Inc. 8430 1-(3-Chlorophenyl)piperazine 6640-24-0 25mg $2000 2021-12-16 Buy
Product number Packaging Price Buy
006596 250mg $509 Buy
C379590 1g $240 Buy
JK287024 5g $59 Buy
JK287024 25g $219 Buy
8430 25mg $2000 Buy

1-(3-Chlorphenyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow oily liquid

Uses

It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

Definition

ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Hazard

A poison.

1-(3-Chlorphenyl)piperazine synthesis

108-37-2
6640-24-0
Synthesis of 1-(3-Chlorphenyl)piperazine from 3-Bromochlorobenzene

1-(3-Chlorphenyl)piperazine Preparation Products And Raw materials

Raw materials

7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, (1R,2S,3R,4S)-rel- tert-butyl 4-(3-chlorophenyl)piperazine-1-carboxylate 1-Chloro-3-iodobenzene Nornitrogen mustard 1-Bromo-3-iodobenzene
Piperazine 1,3-Dichlorobenzene 3-Bromochlorobenzene 3-Chloroaniline Bis(2-chloroethyl)amine hydrochloride
Diethanolamine 1-BOC-Piperazine

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Preparation Products

6640-24-0(1-(3-Chlorphenyl)piperazine)Related Search:

1-(3-Chlorphenyl)piperazine 1-(2,5-Dichlorophenyl)piperazine dihydrochloride 1-(2,3-Dichlorophenyl)-piperazine 1-(4-CHLOROPHENYL)PIPERAZINE DIHYDROCHLORIDE,1-(4-CHLOROPHENYL)-PIPERAZINE 2HCL 1-(4-Chlorophenyl)piperazin-2-one
1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE,1-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE 1-(2,3-Dichlorophenyl)piperazine hydrochloride 1-(3-Chlorophenyl)piperazine hydrochloride 1-(2-Chlorophenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochloride
1-(4-Chlorophenyl)piperazine 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride 3-(4-Chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester 1-(3,5-Dichlorophenyl)piperazine N-(3,4-Dichlorophenyl)piperazine hydrochloride
1-(2,3-Dichlorophenyl)piperazine hydrobromide 1-(2,4-Dichlorobenzyl)piperazine 1-(4-Chlorophenyl)piperazine hydrochloride

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RARECHEM AH CK 0071 N-(3-CHLOROPHENYL)PIPERAZINE TIMTEC-BB SBB003579 MCPP 1-(3-CHLORPHENYL)-PIPERAZINE 1-(3-Chlorophenyl)piperazine 97% 1-(3-CHLOROPHENYL)PIPERAZINE (MCPP) 3-chlorophenyl piperazine AKOS BBS-00003580 1-(3-CHLOROPHENYL)PIPERAZINE HBR 1,3ChlorofenylPiperazine 3-Chlorophenyl-1-Piperazine CHLOROPHENYLPIPERAZINE 4-(3-Chlorophenyl)piperazine N-(m-Chlorophenyl)piperazine NSC 49307 Piperazine, 1-(3-chlorophenyl)- 1-(3-Chlorophenyl)piperazine ,98％ m-Chlorophenylpiperazine 1-(3-Chlorophenyl)piperazine,95% Piperazine, 1-(3-chlorophenyl)-, monohydrochloride Piperazine, 1-(m-chlorophenyl)-, monohydrochloride N-(3-Chlorophenyl) piperazine 1-(3-Chlorophenyl) piperazine Metachlorophenyl Piprazine 1-(3-CHLOROPHENYL) PIPERAZINE ( CPP ) 1-(3-CHLOROPHENYL)PIPERAZINE 6640-24-0 39512-50-01 5-HT2c serotonin receptor agonist; metabolite of trazodone. FOR TRAZODONE'S PRODUCTION Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals PHARMACEUTICAL INTERMEDIATES Piperidines, Piperidones, Piperazines Piperaizine API intermediates Piperazines