1-(3-Chlorphenyl)piperazine

1-(3-Chlorphenyl)piperazine Basic information

Product Name:	1-(3-Chlorphenyl)piperazine
Synonyms:	RARECHEM AH CK 0071;N-(3-CHLOROPHENYL)PIPERAZINE;TIMTEC-BB SBB003579;MCPP;1-(3-CHLORPHENYL)-PIPERAZINE;1-(3-CHLOROPHENYL)PIPERAZINE;1-(3-Chlorophenyl)piperazine 97%;1-(3-CHLOROPHENYL)PIPERAZINE (MCPP)
CAS:	6640-24-0
MF:	C10H13ClN2
MW:	196.68
EINECS:	229-654-7
Product Categories:	FOR TRAZODONE'S PRODUCTION;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;PHARMACEUTICAL INTERMEDIATES;Piperidines, Piperidones, Piperazines;Piperaizine;API intermediates;Piperazines
Mol File:	6640-24-0.mol

1-(3-Chlorphenyl)piperazine Chemical Properties

Melting point	210-214°C
Boiling point	105 °C
density	1.193
refractive index	1,598-1,600
storage temp.	-20°C Freezer, Under Inert Atmosphere
solubility	Chloroform (Slightly), Methanol (Sparingly)
pka	8.85±0.10(Predicted)
form	Oil
color	Colourless to Orange
LogP	2.468
CAS DataBase Reference	6640-24-0(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
3-Chlorophenyl piperazine	English

1-(3-Chlorphenyl)piperazine Usage And Synthesis

Chemical Properties	clear colorless to light yellow oily liquid
Uses	It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
Definition	ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Hazard	A poison.

1-(3-Chlorphenyl)piperazine Preparation Products And Raw materials

Raw materials

Tag:1-(3-Chlorphenyl)piperazine(6640-24-0) Related Product Information

1-(3-Chlorphenyl)piperazine 1-(M-CHLOROPHENYL) PIPERAZINE HYDROCHLORIDE,1-(3-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE N-(3,4-DICHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 4-(4-Chlorophenyl)piperazine,1-(4-CHLOROPHENYL)PIPERAZINE 1-(2,3-DICHLOROPHENYL)PIPERAZINE HYDROBROMIDE 3-(4-CHLOROPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-(2,5-Dichlorophenyl)piperazine dihydrochloride 1-(4-Chlorophenyl)piperazin-2-one 1-(2,4-DICHLOROBENZYL)PIPERAZINE 1-(3,5-DICHLOROPHENYL)PIPERAZINE 1-(4-CHLOROPHENYL)PIPERAZINE DIHYDROCHLORIDE,1-(4-CHLOROPHENYL)-PIPERAZINE 2HCL 1-(2,3-Dichlorophenyl)-piperazine 1-(3-CHLOROPROPYL)-4-(3-CHLOROPHENYL)PIPERAZINE HCL 1-(2-CHLOROPHENYL)PIPERAZINE,1-(o-Chlorophenyl)piperazine 1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE,1-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE 1-(2,3-Dichlorophenyl)piperazine hydrochloride 1-(4-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE,1-(4-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE 1-(3-Chlorophenyl)piperazine hydrochloride

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