1-N-Cbz-3-hydroxy-piperidine
- CAS No.
- 95798-22-4
- Chemical Name:
- 1-N-Cbz-3-hydroxy-piperidine
- Synonyms
- BUTTPARK 99\04-58;N-Cbz-3-hydroxypiperidine;1-Cbz-3-hydroxy-piperidine;1-N-Cbz-3-hydroxy-piperidine;1-Cbz-3-hydroxy-piperidine - [H12297];1-BENZYLOXYCARBONYL-3-HYDROXYPIPERIDINE;1-N-CBZ-3-HYDROXY-PIPERIDINE ISO 9001：2015 REACH;3-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;BENZYL 3-HYDROXYTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE;1-Piperidinecarboxylic acid, 3-hydroxy-, phenylMethyl ester
- CBNumber:
- CB6365486
- Molecular Formula:
- C13H17NO3
- Molecular Weight:
- 235.28
- MDL Number:
- MFCD03839903
- MOL File:
- 95798-22-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| NFPA 704 |
|
1-N-Cbz-3-hydroxy-piperidine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 58144 | 1-N-CBZ-3-HYDROXY-PIPERIDINE 97% | 95798-22-4 | 5G | $33 | 2026-04-30 | Buy |
| AstaTech | 58144 | 1-N-CBZ-3-HYDROXY-PIPERIDINE 97% | 95798-22-4 | 25G | $98 | 2026-04-30 | Buy |
| AstaTech | 58144 | 1-N-CBZ-3-HYDROXY-PIPERIDINE 97% | 95798-22-4 | 100G | $246 | 2026-04-30 | Buy |
| Matrix Scientific | 119286 | Benzyl 3-hydroxypiperidine-1-carboxylate | 95798-22-4 | 1.00g | $82 | 2026-05-18 | Buy |
| Matrix Scientific | 119286 | Benzyl 3-hydroxypiperidine-1-carboxylate | 95798-22-4 | 5.00g | $233 | 2026-05-18 | Buy |
1-N-Cbz-3-hydroxy-piperidine Chemical Properties, Uses, Production
Uses
Benzyl 3-hydroxytetrahydropyridinecarboxylate is a carboxylic acid ester organic compound that can be used as a pharmaceutical intermediate.
Synthesis
64051-79-2
501-53-1
95798-22-4
General procedure for the synthesis of N-Benzyloxycarbonyl-3-hydroxypiperidine from 3-hydroxypiperidine hydrochloride and benzyl chloroformate: Na2CO3 (23.10 g, 218 mmol) was added to a solution of THF/H2O (50 mL/50 mL) containing 3-hydroxypiperidine hydrochloride (10.00 g, 73 mmol). Benzyl chloroformate (14.90 g, 87 mmol) was added dropwise at room temperature and the reaction mixture was stirred for 5 hours. After the reaction was completed, the mixture was extracted with EtOAc (100 mL x 3). The organic layers were combined, washed with brine, dried over anhydrous magnesium sulfate, filtered and concentrated. The resulting residue was purified by silica gel column chromatography with EtOAc/petroleum ether (1/100~1/4, v/v) as eluent to afford N-benzyloxycarbonyl-3-hydroxypiperidine (16.50 g, 96%) as a colorless oil. detected by TLC: Rf = 0.65 (silica gel plate, EtOAc/petroleum ether = 1/1, v/v).
References
[1] Patent: WO2014/32, 2014, A1. Location in patent: Page/Page column 44; 45
[2] Patent: WO2014/68527, 2014, A1. Location in patent: Page/Page column 75; 15
1-N-Cbz-3-hydroxy-piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Sichuan Guanghan Bio-Tech Co., Ltd | +86-28-86127071 | info@sino-produce.com | China | 400 | 66 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 |
View Latest Price from 1-N-Cbz-3-hydroxy-piperidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 1-N-CBZ-3-HYDROXY-PIPERIDINE
95798-22-4
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-06 | 1-N-CBZ-3-HYDROXY-PIPERIDINE
95798-22-4
|
$1.00 | 1KG | 98% | 1ton | Career Henan Chemical Co |
-
- 1-N-CBZ-3-HYDROXY-PIPERIDINE
95798-22-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 1-N-CBZ-3-HYDROXY-PIPERIDINE
95798-22-4
- $1.00
- 98%
- Career Henan Chemical Co
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