ChemicalBook >> CAS DataBase List >>1-Ethylpiperazine
1-Ethylpiperazine
- CAS No.
- 5308-25-8
- Chemical Name:
- 1-Ethylpiperazine
- Synonyms
- N-ETHYLPIPERAZINE;NEPRZ;1-Ethylperazine;N-Ethylpiperazin;AKOS BBS-00003610;1-ETHYLPIPERAZINE;ETHYLPIPERAZINE-N;1-ethyl-piperazin;1-ethvlpiperazine;N-Alkylpiperazine
- CBNumber:
- CB6384137
- Molecular Formula:
- C6H14N2
- Molecular Weight:
- 114.19
- MDL Number:
- MFCD00059912
- MOL File:
- 5308-25-8.mol
Last updated:2025-09-25 17:15:13
| Product description | Number | Pack Size | Price |
| 1-Ethylpiperazine United States Pharmacopeia (USP) Reference Standard | 1266802 | 0.5ml | $1760 |
| 1-Ethylpiperazine 98% | 415308 | 50ml | $48 |
| 1-Ethylpiperazine >98.0%(GC)(T) | E0355 | 25mL | $21 |
| 1-Ethylpiperazine >98.0%(GC)(T) | E0355 | 100mL | $46 |
| 1-Ethylpiperazine 98% | 415308 | 250ml | $145 |
| More product size | |||
| Melting point | -60 °C |
|---|---|
| Boiling point | 157 °C(lit.) |
| Density | 0.899 g/mL at 25 °C(lit.) |
| vapor pressure | 2.48hPa at 20℃ |
| refractive index |
n |
| Flash point | 110 °F |
| storage temp. | 2-8°C |
| solubility | soluble |
| form | Liquid |
| pka | 9.27±0.10(Predicted) |
| Specific Gravity | 0.899 |
| color | Clear colorless to yellow |
| Water Solubility | soluble |
| Sensitive | Air Sensitive |
| BRN | 102971 |
| InChIKey | WGCYRFWNGRMRJA-UHFFFAOYSA-N |
| LogP | -0.1 at 20℃ |
| CAS DataBase Reference | 5308-25-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 6W2BW0V73G |
| NIST Chemistry Reference | N-ethylpiperazine(5308-25-8) |
| EPA Substance Registry System | Piperazine, 1-ethyl- (5308-25-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302+H332-H314-H317-H335 | |||||||||
| Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Hazard | |||||||||
| Risk Statements | 36/37/38-10 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | TM0815500 | |||||||||
| F | 10-34 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29335995 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
1-Ethylpiperazine price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1266802 | 1-Ethylpiperazine United States Pharmacopeia (USP) Reference Standard | 5308-25-8 | 0.5ml | $1760 | 2025-07-31 | Buy |
| Sigma-Aldrich | 415308 | 1-Ethylpiperazine 98% | 5308-25-8 | 50ml | $48 | 2024-03-01 | Buy |
| TCI Chemical | E0355 | 1-Ethylpiperazine >98.0%(GC)(T) | 5308-25-8 | 25mL | $21 | 2025-07-31 | Buy |
| TCI Chemical | E0355 | 1-Ethylpiperazine >98.0%(GC)(T) | 5308-25-8 | 100mL | $46 | 2025-07-31 | Buy |
| Sigma-Aldrich | 415308 | 1-Ethylpiperazine 98% | 5308-25-8 | 250ml | $145 | 2024-03-01 | Buy |
1-Ethylpiperazine Chemical Properties,Uses,Production
Chemical Properties
clear colorless to yellow liquid
Uses
1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.
Uses
1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.
Synthesis Reference(s)
The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621
Flammability and Explosibility
Flammable
1-Ethylpiperazine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Global( 546)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8772 | 58 |
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12247 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from 1-Ethylpiperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-17 | 1-Ethylpiperazine
5308-25-8
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-08-08 | 1-Ethylpiperazine
5308-25-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Sichuan Zhuoyu Yantang Technology Co., Ltd. | |
 |
2025-07-31 | Abemaciclib Impurity 38
5308-25-8
|
US $0.00-0.00 / mg | 10mg | 95%+ | 10000 | Moxin Chemicals |
-
- 1-Ethylpiperazine
5308-25-8
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1-Ethylpiperazine
5308-25-8
- US $0.00 / KG
- 99%
- Sichuan Zhuoyu Yantang Technology Co., Ltd.
-
- Abemaciclib Impurity 38
5308-25-8
- US $0.00-0.00 / mg
- 95%+
- Moxin Chemicals
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