(R)-N-Boc-3-pyrrolidineacetic acid
- CAS No.
- 204688-60-8
- Chemical Name:
- (R)-N-Boc-3-pyrrolidineacetic acid
- Synonyms
- (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(R)-N-Boc-3-pyrrolidineacetic;(R)-1-Boc-3-pyrrolidineacetic acid;N-BOC-(R)-pyrrolidin-3-acetic acid;(R)-N-BOC-3-PYRROLIDINEACETIC ACID;(R)-N-BOC-PYRROLIDINE-3-ACETIC ACID;(3R)-1-Boc-3-pyrrolidineacetic acid;(R)-1-N-Boc-3-pyrrolidineacetic acid;(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid;(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID
- CBNumber:
- CB6409081
- Molecular Formula:
- C11H19NO4
- Molecular Weight:
- 229.27
- MDL Number:
- MFCD05861547
- MOL File:
- 204688-60-8.mol
- MSDS File:
- SDS
| Boiling point | 357.4±15.0 °C(Predicted) |
|---|---|
| Density | 1.151±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.65±0.10(Predicted) |
| InChI | InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-5-4-8(7-12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m1/s1 |
| InChIKey | SKEXQIJIXQSFRX-MRVPVSSYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CC[C@H](CC(O)=O)C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| Hazard Codes | T,N |
| Risk Statements | 25-50 |
| Safety Statements | 45-61 |
| RIDADR | UN2811 |
| HS Code | 2933998090 |
(R)-N-Boc-3-pyrrolidineacetic acid price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 55506 | (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID 97% | 204688-60-8 | 0.25G | $17 | 2026-04-30 | Buy |
| AstaTech | 55506 | (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID 97% | 204688-60-8 | 1G | $21 | 2026-04-30 | Buy |
| AstaTech | 55506 | (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID 97% | 204688-60-8 | 5G | $33 | 2026-04-30 | Buy |
| Matrix Scientific | 122851 | (R)-1-Boc-3-pyrrolidine acetic acid | 204688-60-8 | 25.00g | $97 | 2026-05-18 | Buy |
| Matrix Scientific | 122851 | (R)-1-Boc-3-pyrrolidine acetic acid | 204688-60-8 | 100.00g | $377 | 2026-05-18 | Buy |
(R)-N-Boc-3-pyrrolidineacetic acid Chemical Properties, Uses, Production
Uses
(R)-N-Boc-3-tetrahydropyrrolic acid is an important pharmaceutical synthesis intermediate widely used in organic synthesis. It can act as an introducing agent for amine protecting groups, protecting the amine groups from side reactions during synthesis.
Synthesis
(R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.
(R)-N-Boc-3-pyrrolidineacetic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Dorher Pharmaceutical CO.,Ltd | 028-64259743 19983537320 | wangmin@focuspharm.com | China | 498 | 58 |
| Sichuan Lancent Medical Devices Co., Ltd. | 18111675298 | stochem@aliyun.com | China | 215 | 58 |
| Jiaxing Deyi Chemical Co., Ltd | 0573-85866609 13325730825 | jiaxingshidy@163.com | China | 7898 | 58 |
| Shanghai Hobor Chemical Co., Ltd | 13918007836 | sales@hoborchem.com | China | 423 | 60 |
| Wuhan Ruilida Biomedical Technology Co., Ltd. | 18201884268 | magean83@163.com | China | 2512 | 58 |
| ACME BIOPHARMA CO., LTD. | 19071409695 19071409695 | acmewh@163.com | China | 203 | 58 |
| Shandong Longchen Pharmaceutical Co., Ltd. | 15964061209 15964061209 | yangyy@longzenpharma.com | China | 356 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| ITIC MEDCHEM(SUZHOU) CO.,LTD. | 0512-68323967 18015559028 | sales@iticmedchem.com | China | 528 | 61 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Latest Price from (R)-N-Boc-3-pyrrolidineacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-20 | (R)-N-Boc-3-pyrrolidineacetic acid
204688-60-8
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- (R)-N-Boc-3-pyrrolidineacetic acid
204688-60-8
- $1.00
- 99%
- Career Henan Chemical Co
204688-60-8 ((R)-N-Boc-3-pyrrolidineacetic acid) Related Search:
1of4
