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ChemicalBook >> CAS DataBase List >>D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Structure
D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol structure
CAS No.
716-61-0
Chemical Name:
D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Synonyms
(1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL;ChloromycinbaseL-base;levoamine;Chloromycin base;L-amino compound;L-BASE (AMINODIOL);chloramphenicolbase;D(-)Threo-1-(4-nitro;Refined L-amino compound;Chloramphenicol impurity D
CBNumber:
CB6452870
Molecular Formula:
C9H12N2O4
Molecular Weight:
212.2
MDL Number:
MFCD00078126
MOL File:
716-61-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:16
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D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Properties

Melting point 163-165 °C(lit.)
Boiling point 352.03°C (rough estimate)
Density 1.3136 (rough estimate)
refractive index -30.5 ° (C=1, 6mol/L HCl)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
Water Solubility almost transparency in hot Water
solubility DMSO (Slightly), Methanol (Slightly)
form Powder
pka 10.98±0.45(Predicted)
color Light yellow
optical activity [α]25/D 30°, c = 1 in 6 M HCl
InChI InChI=1S/C9H12N2O4/c10-8(5-12)9(13)6-1-3-7(4-2-6)11(14)15/h1-4,8-9,12-13H,5,10H2/t8-,9-/m1/s1
InChIKey OCYJXSUPZMNXEN-RKDXNWHRSA-N
SMILES [C@H](C1=CC=C([N+]([O-])=O)C=C1)(O)[C@H](N)CO
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,T
Risk Statements  22-36/37/38-45
Safety Statements  26-45-53-22
RIDADR  UN 3259 8/PG 3
WGK Germany  3
RTECS  TY3100000
HazardClass  8
HS Code  29221990
REACH Registrations Active
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
2 0

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A70704 (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% 716-61-0 10g $118 2026-04-30 Buy
Sigma-Aldrich C3175 Chloramphenicol-Water Soluble powder, BioReagent, suitable for cell culture 100 mg $118 2026-04-30 Buy
Sigma-Aldrich A70704 (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% 716-61-0 25g $161 2026-04-30 Buy
TCI Chemical A1017 D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) 716-61-0 25g $79 2026-04-30 Buy
TCI Chemical A1017 D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) 716-61-0 500g $689 2026-04-30 Buy
Product number Packaging Price Buy
A70704 10g $118 Buy
C3175 100 mg $118 Buy
A70704 25g $161 Buy
A1017 25g $79 Buy
A1017 500g $689 Buy

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Chemical Properties, Uses, Production

Chemical Properties

light yellow powder

Uses

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.

Uses

Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

Uses

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].

Definition

ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Preparation Products And Raw materials

Raw materials

Propiophenone

Preparation Products

Potassium heptadecafluoro-1-octanesulfonate

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Suppliers

Global Suppliers ( 264)
Supplier Tel Email Country ProdList Advantage
Yancheng Huahong Chemical Co., Ltd. 15366451979 sales@huahongchem.com China 23 58
Ningbo biermann pharmaceutical technology co., LTD 0571-82572971 13736400971 bichem.sales01@bichem.cn China 47 58
Beijing Bainiannuan Sci.&Tec. Co., Ltd 13240490036 marymeng@bdnchem.com China 35 58
Ningbo Enzyme Chemical Co., LTD 0574-+86-574-8773-0716-654-654 18042089573 yufang.jiang@enzymaster.com China 42 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Yancheng Huahong Chemical Co., Ltd. 58
Ningbo biermann pharmaceutical technology co., LTD 58
Beijing Bainiannuan Sci.&Tec. Co., Ltd 58
Ningbo Enzyme Chemical Co., LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60

View Latest Price from D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-amino compound pictures 2026-09-16 L-amino compound
716-61-0
 25kg 99% 2000 HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL pictures 2026-06-30 D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
716-61-0
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
ChloromycinbaseL-base pictures 2025-06-27 ChloromycinbaseL-base
716-61-0
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Spectrum

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)MSD-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)1HNMRD-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)IR1D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)IR2D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)Raman

716-61-0 (D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol) Related Search:

Chloramphenicol palmitate D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 2-Amino-1-(4-nitrophenyl)-1,3-propanediol Nitrophenol 2-Amino-1,3-propanediol
(1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol Chloramphenicol Chloramphenicol sodium succinate Eusynthomycin BROMAMPHENICOL
CHLORAMPHENICOL (D5) CHLORAMPHENICOL-ALCOHOL (1R,2R)-B13 L-(+)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chloramphenicol 1-O-beta-D-galactopyranoside
D-threo-[Dichloroacetyl-1-14C]-chloramphenicol Fmoc-(1R,2R)-(-)-2-amino-1-(4-nitrophenyl)-1,3-propanediol Boc-(1R,2R)-(-)-2-amino-1-(4-nitrophenyl)-1,3-propanediol

1of4

ChloromycinbaseL-base D-(-)-THREO-2-AMINO-1-(4-NITRO (1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol [1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96% (1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base (1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99% (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96% (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride L-BASE (AMINODIOL) D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay) d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol levoamine Chloromycin base 2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)- chloramphenicolbase Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol (1R,2R)-(-)-2-Amino-1-(4-nitrophenyL D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL CHLORAMPHENICOL-WATER SOLUBLE (1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL (1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL CHLORAMPHENICOL BASE CRYSTALLINE (1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99% D(-)Threo-1-(4-nitro-phenyl)-2 1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)- D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE (1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol nitrate Chloramphenicol impurity D (D)-(-)-threo-2-Amino-1-(4-nitrophe Chloramphenicol Impurity 1 (D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol) D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol > Chloramphenicol Impurity 1 D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL USP/EP/BP D(-)Threo-1-(4-nitro (1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-aminium Chloramphenicol Impurity A D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol/D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Aminonitrophenolpropanediol D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol, ≥ 98.0% 2-[(1R,2R)-2-amino-1,3-dihydroxypropyl]benzoic acid L-amino compound (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Refined L-amino compound D (-) Su-1-p-nitrophenyl-2-amino-1,3-propanediol (1R,2R)-2-Amino-1-(4-nitrophenyl)-propan-1,3-diol (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 716-61-0 C9H12O4N2 C9H13N2O4 HOCH2CHNH2CHC6H4NO2OH AMINE