D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
- CAS No.
- 716-61-0
- Chemical Name:
- D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
- Synonyms
- (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL;ChloromycinbaseL-base;levoamine;Chloromycin base;L-amino compound;L-BASE (AMINODIOL);chloramphenicolbase;D(-)Threo-1-(4-nitro;Refined L-amino compound;Chloramphenicol impurity D
- CBNumber:
- CB6452870
- Molecular Formula:
- C9H12N2O4
- Molecular Weight:
- 212.2
- MDL Number:
- MFCD00078126
- MOL File:
- 716-61-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% | A70704 | 10g | $118 |
| Chloramphenicol-Water Soluble powder, BioReagent, suitable for cell culture | C3175 | 100 mg | $118 |
| (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% | A70704 | 25g | $161 |
| D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) | A1017 | 25g | $79 |
| D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) | A1017 | 500g | $689 |
| More product size | |||
| Melting point | 163-165 °C(lit.) |
|---|---|
| Boiling point | 352.03°C (rough estimate) |
| Density | 1.3136 (rough estimate) |
| refractive index | -30.5 ° (C=1, 6mol/L HCl) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| Water Solubility | almost transparency in hot Water |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 10.98±0.45(Predicted) |
| color | Light yellow |
| optical activity | [α]25/D 30°, c = 1 in 6 M HCl |
| InChI | InChI=1S/C9H12N2O4/c10-8(5-12)9(13)6-1-3-7(4-2-6)11(14)15/h1-4,8-9,12-13H,5,10H2/t8-,9-/m1/s1 |
| InChIKey | OCYJXSUPZMNXEN-RKDXNWHRSA-N |
| SMILES | [C@H](C1=CC=C([N+]([O-])=O)C=C1)(O)[C@H](N)CO |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-36/37/38-45 | |||||||||
| Safety Statements | 26-45-53-22 | |||||||||
| RIDADR | UN 3259 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TY3100000 | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 29221990 | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A70704 | (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% | 716-61-0 | 10g | $118 | 2026-04-30 | Buy |
| Sigma-Aldrich | C3175 | Chloramphenicol-Water Soluble powder, BioReagent, suitable for cell culture | 100 mg | $118 | 2026-04-30 | Buy | |
| Sigma-Aldrich | A70704 | (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 99% | 716-61-0 | 25g | $161 | 2026-04-30 | Buy |
| TCI Chemical | A1017 | D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) | 716-61-0 | 25g | $79 | 2026-04-30 | Buy |
| TCI Chemical | A1017 | D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol >98.0%(T) | 716-61-0 | 500g | $689 | 2026-04-30 | Buy |
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chemical Properties,Uses,Production
Chemical Properties
light yellow powder
Uses
D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.
Uses
Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.
Uses
(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].
Definition
ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-20 | L-amino compound
716-61-0
|
25kg | 99% | 2000 | HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD
|
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2026-06-30 | D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
716-61-0
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2025-06-27 | ChloromycinbaseL-base
716-61-0
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-

- L-amino compound
716-61-0
- $0.00
- 99%
- HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD
-

- D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
716-61-0
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-

- ChloromycinbaseL-base
716-61-0
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Spectrum
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