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ChemicalBook >> CAS DataBase List >>5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester Structure
5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester structure
CAS No.
99632-94-7
Chemical Name:
5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester
Synonyms
RO 19-4603;Ro 194603,Ro 19 4603;5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylicacid1,1-dimethylethylester;5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester;4H-Imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, 1,1-dimethylethyl ester
CBNumber:
CB6465061
Molecular Formula:
C15H17N3O3S
Molecular Weight:
319.38
MDL Number:
MFCD00877822
MOL File:
99632-94-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:16
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5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester Properties

storage temp. Store at RT
solubility <31.94mg/ml in ethanol; <31.94mg/ml in DMSO

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology B6913 Ro 19-4603 99632-94-7 10mg $264 2026-05-06 Buy
ApexBio Technology B6913 Ro 19-4603 99632-94-7 50mg $1106 2026-05-06 Buy
Usbiological 256477 Ro 19-4603 99632-94-7 10mg $409 2021-12-16 Buy
American Custom Chemicals Corporation CHM0972477 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER 95.00% 99632-94-7 5MG $504.41 2021-12-16 Buy
Product number Packaging Price Buy
B6913 10mg $264 Buy
B6913 50mg $1106 Buy
256477 10mg $409 Buy
CHM0972477 5MG $504.41 Buy

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester Chemical Properties, Uses, Production

Uses

Ro 19-4603 is a novel benzodiazepine inverse agonist.

Definition

ChEBI: Ro 19-4603 is an organonitrogen heterocyclic compound, an organosulfur heterocyclic compound and a tert-butyl ester.

Biological Activity

Benzodiazepine inverse agonist. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABA A receptors (K i values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Antagonizes effects of ethanol on locomotor behavior and suppresses ethanol intake in alcohol-preferring rats.

in vivo

Ro19-4603 (0-0.3 mg/kg, i.p.) markedly reduces EtOH intake at the 8-h interval in alcohol-preferring rats[1].

Animal Model:Alcohol-Preferring rats[1]
Dosage:0.075, 0.150, and 0.30 mg/kg.
Administration:i.p.
Result:Reduced EtOH intake at the 8-h interval, but no apparent effect at the 24-h interval.

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 1999 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000 jinoupharma@163.com China 11706 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
HangZhou YuHao Chemical Technology Co., Ltd. 58
EMMX Biotechnology LLC 60
TargetMol Chemicals Inc. 58
MedBioPharmaceutical Technology Inc 58
JinOu Biomedical (Nanjing) Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ro 19-4603 pictures 2026-05-11 Ro 19-4603
99632-94-7
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
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    99632-94-7
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99632-94-7 (5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester) Related Search:

1-Methyl-1H-imidazole-4-carboxylic acid 1-METHYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester 1,5-Dimethyl-1H-imidazole-4-carbaldehyde (1-Methyl-1H-imidazol-4-yl)methanol
DHEA-S

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RO 19-4603 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylicacid1,1-dimethylethylester 4H-Imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, 1,1-dimethylethyl ester Ro 194603,Ro 19 4603 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester 99632-94-7