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ChemicalBook >> CAS DataBase List >>2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Structure
2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate structure
CAS No.
663598-61-6
Chemical Name:
2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate
Synonyms
NO2-SPP;2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate;Pentanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB64903352
Molecular Formula:
C14H15N3O6S2
Molecular Weight:
385.42
MDL Number:
MFCD20230055
MOL File:
663598-61-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:19:23
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2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Properties

Boiling point 548.7±60.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
pka -2.22±0.29(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-45197 2,5-Dioxo-1-pyrrolidinyl 4-[(5-nitro-2-pyridinyl)dithio]pentanoate 663598-61-6 100MG $250 2026-05-24 Buy
BroadPharm bp-45197 2,5-Dioxo-1-pyrrolidinyl 4-[(5-nitro-2-pyridinyl)dithio]pentanoate 663598-61-6 250MG $550 2026-05-24 Buy
BroadPharm bp-45197 2,5-Dioxo-1-pyrrolidinyl 4-[(5-nitro-2-pyridinyl)dithio]pentanoate 663598-61-6 500MG $980 2026-05-24 Buy
BroadPharm bp-45197 2,5-Dioxo-1-pyrrolidinyl 4-[(5-nitro-2-pyridinyl)dithio]pentanoate 663598-61-6 1G $1650 2026-05-24 Buy
aablocks AA003FXW 2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate techgrade 663598-61-6 50mg $380 2026-05-28 Buy
Product number Packaging Price Buy
bp-45197 100MG $250 Buy
bp-45197 250MG $550 Buy
bp-45197 500MG $980 Buy
bp-45197 1G $1650 Buy
AA003FXW 50mg $380 Buy

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Chemical Properties, Uses, Production

Uses

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Qiming Chen, et al. Anti-integrin immunoconjugates, methods and uses. WO2006062779A2.

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Suppliers

Global Suppliers ( 16)
Supplier Tel Email Country ProdList Advantage
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Pushan Industry (Shaanxi) Co., Ltd. 029-81310890 18165209495 2929288192@qq.com China 9949 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38904 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Guangzhou Reullei Pharmaceutical Technology Co., Ltd， 13660253774 joe.yang@reullei.com China 4989 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Suzhou ARTK Medchem Co., Ltd. +86-18168183658 sales1@artkmedchem.com China 39007 58
Supplier Advantage
Aikon International Limited 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Pushan Industry (Shaanxi) Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
TargetMol Chemicals Inc. 58
Guangzhou Reullei Pharmaceutical Technology Co., Ltd， 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Suzhou ARTK Medchem Co., Ltd. 58

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2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate NO2-SPP Pentanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-1-pyrrolidinyl ester 663598-61-6