N,N-Dibenzylglycine ethyl ester
- CAS No.
- 77385-90-1
- Chemical Name:
- N,N-Dibenzylglycine ethyl ester
- Synonyms
- Di-Bzl-Gly-OEt;Ethyl 2-(dibenzylamino);Ethyl N,N-dibenzylglycinate;Ethyl (dibenzylamino)acetate;N,N-Dibenzyl-O-ethylglycinate;N,N-dibenzylglycine ethyl este;N,N-Dibenzylglycine ethyl ester;N,N-DibenzylglycineEthylEster>DIBENZYLAMINO-ACETIC ACID ETHYL ESTER;N,N-bis(phenylmethyl)Glycineethyl ester
- CBNumber:
- CB6500724
- Molecular Formula:
- C18H21NO2
- Molecular Weight:
- 283.36
- MDL Number:
- MFCD00796343
- MOL File:
- 77385-90-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 56 °C |
|---|---|
| Boiling point | 376℃ |
| Density | 1.091 |
| Flash point | 123℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 5.47±0.50(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C18H21NO2/c1-2-21-18(20)15-19(13-16-9-5-3-6-10-16)14-17-11-7-4-8-12-17/h3-12H,2,13-15H2,1H3 |
| InChIKey | AFMDCFOWHWNQBP-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)CN(CC1=CC=CC=C1)CC1=CC=CC=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2922.49.3700 |
N,N-Dibenzylglycine ethyl ester price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R243361 | DIBENZYLAMINO-ACETIC ACID ETHYL ESTER AldrichCPR | 77385-90-1 | 50MG | $32.7 | 2026-04-30 | Buy |
| TCI Chemical | D3165 | N,N-Dibenzylglycine Ethyl Ester >98.0%(GC)(N) | 77385-90-1 | 5g | $105 | 2026-04-30 | Buy |
| TCI Chemical | D3165 | N,N-Dibenzylglycine Ethyl Ester >98.0%(GC)(N) | 77385-90-1 | 25g | $416 | 2026-04-30 | Buy |
| TRC | TRC-D418230-500MG | N,N-Dibenzylglycine Ethyl Ester | 77385-90-1 | 500mg | $91 | 2026-06-03 | Buy |
| TRC | TRC-D418230-250MG | N,N-Dibenzylglycine Ethyl Ester | 77385-90-1 | 250mg | $78 | 2026-06-03 | Buy |
N,N-Dibenzylglycine ethyl ester Chemical Properties,Uses,Production
Chemical Properties
White to almost white crystalline powder
Synthesis
623-73-4
103-49-1
77385-90-1
GENERAL STEPS: A solution of dibenzylamine (0.3 mmol, dissolved in 4.0 mL of ether) was added to a solution of water (1.0 mL) containing Ru(II)-hm-pheox 3 (0.0075 mmol, 2.5 mol%), followed by the addition of ethyl diazidoacetate (0.3 mmol, 1.0 equiv). The two-phase reaction mixture was stirred at room temperature until the reaction was complete. At the end of the reaction, the ether layer was separated and removed by decantation, and the catalyst in the aqueous phase was washed three times with ether (3 x 5.0 mL). The combined ether phases contained the ethyl 2-(dibenzylamino)acetate product, which was dried over anhydrous Na2SO4 and concentrated under reduced pressure. In most cases, the purity of the product is sufficient and no further purification is required. The aqueous phase containing the catalyst can be recovered for reuse. For purification of the 2-piperazinone product, silica gel column chromatography was used, using only methanol as eluent.
References
[1] Tetrahedron Letters, 2017, vol. 58, # 51, p. 4750 - 4754
[2] Asian Journal of Chemistry, 2017, vol. 29, # 2, p. 349 - 352
[3] Tetrahedron Letters, 2014, vol. 55, # 40, p. 5417 - 5419
[4] Angewandte Chemie - International Edition, 2012, vol. 51, # 22, p. 5351 - 5354
[5] Tetrahedron Letters, 2009, vol. 50, # 31, p. 4467 - 4469
N,N-Dibenzylglycine ethyl ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 1846 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Lastest Price from N,N-Dibenzylglycine ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | N,N-DIBENZYLGLYCINE ETHYL ESTER
77385-90-1
|
$100.00 | 1KG | 99% | Career Henan Chemical Co |
-
- N,N-DIBENZYLGLYCINE ETHYL ESTER
77385-90-1
- $100.00
- 99%
- Career Henan Chemical Co
