Glycine methyl ester hydrochloride
- CAS No.
- 5680-79-5
- Chemical Name:
- Glycine methyl ester hydrochloride
- Synonyms
- METHYL GLYCINATE HYDROCHLORIDE;GLYCINE METHYL ESTER HCL;METHYL GLYCINATE HCL;AMINOACETIC ACID METHYL ESTER HYDROCHLORIDE;MURA-005;Gly-OmeHCl;ycine MethyL;H-Gly-OMe.HCI;JACS-5680-79-5;GLYCINE-OME HCL
- CBNumber:
- CB6713993
- Molecular Formula:
- C3H8ClNO2
- Molecular Weight:
- 125.55
- MDL Number:
- MFCD00012870
- MOL File:
- 5680-79-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 175 °C (dec.)(lit.) |
|---|---|
| Density | 1.000 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | >1000 g/L (20°C) |
| form | Powder or Cyrstals |
| color | White |
| Water Solubility | >1000 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 3593644 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H |
| InChIKey | COQRGFWWJBEXRC-UHFFFAOYSA-N |
| SMILES | C(=O)(OC)CN.Cl |
| CAS DataBase Reference | 5680-79-5(CAS DataBase Reference) |
| FDA UNII | R9RMX6E8BD |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P271-P261-P280 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29224995 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Glycine methyl ester hydrochloride price More Price(90)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G6600 | Glycine methyl ester hydrochloride 99% | 5680-79-5 | 5g | $55.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | G6600 | Glycine methyl ester hydrochloride 99% | 5680-79-5 | 100g | $68.1 | 2026-04-30 | Buy |
| TCI Chemical | G0246 | Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N) | 5680-79-5 | 25g | $24 | 2026-04-30 | Buy |
| TCI Chemical | G0246 | Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N) | 5680-79-5 | 500g | $100 | 2026-04-30 | Buy |
| Usbiological | 278272 | Glycine methylester HCI Asreported | 5680-79-5 | 250g | $305 | 2026-06-03 | Buy |
Glycine methyl ester hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline
Uses
A Glycine ester, a non-essential amino acid for human development.
Uses
Glycine methyl ester hydrochloride a non-essential amino acid used for human development.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
67-56-1
56-40-6
5680-79-5
(2) Preparation of glycine methyl ester hydrochloride: 60 mL of methanol was added to a 100 mL round-bottomed flask under ice-bath conditions, followed by the slow dropwise addition of 4 mL of sulfoxide chloride (SOCl2) through a constant-pressure dropping funnel (with a drying tube on top). The resulting off-gas was absorbed using NaOH solution. After stirring the reaction mixture for 1 h, 8 mmol of glycine was added and stirring was continued for 30 min at room temperature. Subsequently, the reaction system was warmed up to 66 °C and refluxed for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) using 2% ninhydrin ethanol solution as a color developer until the disappearance of the raw material spot. After completion of the reaction, the solvent was removed by evaporation to give glycine methyl ester hydrochloride in 100% yield.
Purification Methods
Crystallise the ester salt from MeOH. [Werbin & Spoerri J Am Chem Soc 69 1682 1947, Beilstein 4 H 340, 4 III 1116.]
References
[1] Synthetic Communications, 1998, vol. 28, # 3, p. 471 - 474
[2] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788,15
[3] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788
[4] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0131
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 3, p. 695 - 703
Glycine methyl ester hydrochloride Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Xinkang Pharmaceutical Chemical Co., Ltd | 027-027-59308705 18871579363 | 1248680011@qq.com | China | 9279 | 58 |
| Hubei Junrui Biotechnology Co., Ltd | 13971166412 | 2653908223@qq.com | China | 4948 | 58 |
| Nanjing Yihua Biotechnology Co., Ltd | 13429882898; 13429882898 | 1096323105@qq.com | China | 291 | 58 |
| Nanjing Optimal New Materials Technology Co., Ltd. | 180-86404407 17340521416 | 1757224788@qq.com | China | 1011 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Sichuan Tongsheng Amino acids Co.,Ltd. | 0838-2274206 17340404235 | sales@biots.cn | China | 300 | 66 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
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View Lastest Price from Glycine methyl ester hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | H-Gly-Ome.HCl
5680-79-5
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-09-11 | Glycine methyl ester hydrochloride
5680-79-5
|
1kg | 98%min | 10000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-12 | Glycine methyl ester hydrochloride
5680-79-5
|
$58.00 | 1KG | 98% | 1-1000kg | Baoji Guokang Healthchem Co., Ltd. |
-
- H-Gly-Ome.HCl
5680-79-5
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- Glycine methyl ester hydrochloride
5680-79-5
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Glycine methyl ester hydrochloride
5680-79-5
- $58.00
- 98%
- Baoji Guokang Healthchem Co., Ltd.
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