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Glycine methyl ester hydrochloride

Glycine methyl ester hydrochloride structure

CAS No.: 5680-79-5

Chemical Name:: Glycine methyl ester hydrochloride

Synonyms: METHYL GLYCINATE HYDROCHLORIDE;GLYCINE METHYL ESTER HCL;METHYL GLYCINATE HCL;AMINOACETIC ACID METHYL ESTER HYDROCHLORIDE;MURA-005;Gly-OmeHCl;ycine MethyL;H-Gly-OMe.HCI;JACS-5680-79-5;GLYCINE-OME HCL

CBNumber:: CB6713993

Molecular Formula:: C3H8ClNO2

Molecular Weight:: 125.55

MDL Number:: MFCD00012870

MOL File:: 5680-79-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:52

Product description	Number	Pack Size	Price
Glycine methyl ester hydrochloride 99%	G6600	5g	$51.9
Glycine methyl ester hydrochloride 99%	G6600	100g	$63.9
Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N)	G0246	25g	$24
Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N)	G0246	500g	$100
Glycine methyl ester hydrochloride 99%	G6600	500g	$124
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Glycine methyl ester hydrochloride Properties

Melting point	175 °C (dec.)(lit.)
Density	1.000
storage temp.	Inert atmosphere,Room Temperature
solubility	>1000 g/L (20°C)
form	Powder or Cyrstals
color	White
Water Solubility	>1000 g/L (20 ºC)
Sensitive	Hygroscopic
BRN	3593644
Stability	Stable. Incompatible with strong oxidizing agents.
InChI	InChI=1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
InChIKey	COQRGFWWJBEXRC-UHFFFAOYSA-N
SMILES	C(=O)(OC)CN.Cl
CAS DataBase Reference	5680-79-5(CAS DataBase Reference)
FDA UNII	R9RMX6E8BD
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P271-P261-P280

Safety Statements

22-24/25

WGK Germany

HS Code

29224995

NFPA 704

	0
0		0

Glycine methyl ester hydrochloride price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	G6600	Glycine methyl ester hydrochloride 99%	5680-79-5	5g	$51.9	2025-07-31	Buy
Sigma-Aldrich	G6600	Glycine methyl ester hydrochloride 99%	5680-79-5	100g	$63.9	2025-07-31	Buy
TCI Chemical	G0246	Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N)	5680-79-5	25g	$24	2025-07-31	Buy
TCI Chemical	G0246	Glycine Methyl Ester Hydrochloride >97.0%(HPLC)(N)	5680-79-5	500g	$100	2025-07-31	Buy
Sigma-Aldrich	G6600	Glycine methyl ester hydrochloride 99%	5680-79-5	500g	$124	2025-07-31	Buy

Product number	Packaging	Price	Buy
G6600	5g	$51.9	Buy
G6600	100g	$63.9	Buy
G0246	25g	$24	Buy
G0246	500g	$100	Buy
G6600	500g	$124	Buy

Glycine methyl ester hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Crystalline

Uses

A Glycine ester, a non-essential amino acid for human development.

Uses

Glycine methyl ester hydrochloride a non-essential amino acid used for human development.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

67-56-1

56-40-6

5680-79-5

(2) Preparation of glycine methyl ester hydrochloride: 60 mL of methanol was added to a 100 mL round-bottomed flask under ice-bath conditions, followed by the slow dropwise addition of 4 mL of sulfoxide chloride (SOCl2) through a constant-pressure dropping funnel (with a drying tube on top). The resulting off-gas was absorbed using NaOH solution. After stirring the reaction mixture for 1 h, 8 mmol of glycine was added and stirring was continued for 30 min at room temperature. Subsequently, the reaction system was warmed up to 66 °C and refluxed for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) using 2% ninhydrin ethanol solution as a color developer until the disappearance of the raw material spot. After completion of the reaction, the solvent was removed by evaporation to give glycine methyl ester hydrochloride in 100% yield.

Purification Methods

Crystallise the ester salt from MeOH. [Werbin & Spoerri J Am Chem Soc 69 1682 1947, Beilstein 4 H 340, 4 III 1116.]

References

[1] Synthetic Communications, 1998, vol. 28, # 3, p. 471 - 474
[2] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788,15
[3] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788
[4] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0131
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 3, p. 695 - 703

Glycine methyl ester hydrochloride synthesis

Synthesis of Glycine methyl ester hydrochloride from Methanol and Glycine

Glycine methyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Hydrogen chloride ethanol solution Glycine ethyl ester hydrochloride Glycine Methanol Hexamethylenetetramine

Sodium carbonate methyl glycinate

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Preparation Products

2-Ethylpiperazine TOLRESTAT (S)-3-TERT-BUTYL-2,5-PIPERAZINEDIONE 1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4S)-(9CI) 1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)

METHYL N-ACETYLGLYCINATE Glycine, N-(phenylMethyl)-, Methyl ester Azidoacetic acid methyl ester N-Boc-N-methyl glycine methyl ester GLYCYL-L-PHENYLALANINE

Methyl 3-[(methoxycarbonylmethyl)sulfamoyl]thiophene-2-carboxylate methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate N-(DIPHENYLMETHYLENE)GLYCINE METHYL ESTER

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Glycine methyl ester hydrochloride Suppliers

Global( 687)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
DONBOO AMINO ACID COMPANY	+8618051385538	donboo@donboo.com	China	9363	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1100	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55

Supplier	Advantage
DONBOO AMINO ACID COMPANY	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55

View Lastest Price from Glycine methyl ester hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-20	Glycine methyl ester hydrochloride 5680-79-5	US $0.00-0.00 / kg	1kg	98%min	10000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-10-20	H-Gly-Ome.HCl 5680-79-5	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2025-07-29	Glycine methyl ester hydrochloride 5680-79-5	US $58.00 / KG	1KG	98%	1-1000kg	Baoji Guokang Healthchem Co., Ltd.

Glycine methyl ester hydrochloride
5680-79-5
US $0.00-0.00 / kg
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

H-Gly-Ome.HCl
5680-79-5
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Glycine methyl ester hydrochloride
5680-79-5
US $58.00 / KG
98%
Baoji Guokang Healthchem Co., Ltd.

Glycine methyl ester hydrochloride Spectrum

Glycine methyl ester hydrochloride(5680-79-5)MS Glycine methyl ester hydrochloride(5680-79-5)¹HNMR Glycine methyl ester hydrochloride(5680-79-5)¹³CNMR Glycine methyl ester hydrochloride(5680-79-5)IR1 Glycine methyl ester hydrochloride(5680-79-5)IR2 Glycine methyl ester hydrochloride(5680-79-5)Raman

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AMINOACETIC ACID METHYL ESTER HYDROCHLORIDE METHYL GLYCINATE HCL METHYL GLYCINATE HYDROCHLORIDE L-GLYCINE METHYL ESTER HYDROCHLORIDE GLYCINE-OME HCL GLYCINE METHYL ESTER HCL GLYCINE METHYL ESTER HYDROCHLORIDE GLYCINE METHYL ESTER HYDROCHLORIDE SALT GLYCINE METHYL ESTER MONOHYDROCHLORIDE N-[(2-Thienyl)Ethyl]-(2S)-2-Chloro-PhenylGlycineMethylEster Gly-OmeHCl Glycinemethylesterhydrochloride,99% Methyl aminoacetate,hydrochloride Glycine methyl ester hydrochloride≥ 99% (HPLC) Methyl glycinate hydrochloride for synthesis 4-AMINOBENZYL ALCOHOL HCL MURA-005 GLYCINE METHYL ESTER .HCl (5680-79-5) JACS-5680-79-5 ycine MethyL Methyl glutamate Methylglyacinate chlorohydrate 2-Aminoacetic acid methyl·hydrochloride Glycine methyl·hydrochloric acid Glycine methyl ester hydrochloride,98% Glycine methylester HCI Glycine Methyl ester HC1 METHYL GLYCINATE HYDROCHLORIDE FOR SYNTH Glycinate Methyl Ester Hydrochloride Glycine Methyl ester hydrochlor Glycine Methyl ester hydrochloride 99% Glycine Methyl Ester Hydrochloride, 97+% GlyClne methyl ester HCl Glycine methyl/ethyl ester hydrochloride GlycineMethylEsterHydrochloride> Glycine methyl ester hydrochloride USP/EP/BP Glycine methyl ester hydrochloride(5680-79-5) Tolutoacetate hydrochloride RSSYY(Lurasidone Hydrochloride)-1 GlyClne methyl ester HC H-Gly-OMe.HCI Glycine Methyl Ester Hydrochloride (Methyl Glycinate Hydrochloride) Glycine methyI ester hydrochloride Glycine methylester hydrochloride - Assay 99% L-Glycine methyl ester hydrochloride Glycine methyl ester hydrochloride 5680-79-5 A25402 Aminoacetic acid methyl ester hydrochloride Glycine methyl ester hydrochloride, 95% 5680-79-5 A25402 Aminoacetic acid methyl ester hydrochloride 5680-79-5 H2NCH2CO2CH3HCl NH2CH2COOCH3HCl C3H8NO2Cl C3H7NO2HCl C3H8ClNO2 C3H7NO2HClC3H8ClNO2 AMINE Amino Acid Derivatives Specialty Synthesis