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Rhodanine

CAS No.
141-84-4
Chemical Name:
Rhodanine
Synonyms
2-THIOXOTHIAZOLIDIN-4-ONE;Rodanin;Argenton;Rhodanin;usafha-2;RSOdanin;RHODANINE;USAF ha-2;AKOS B029032;usafha-2[qr]
CBNumber:
CB7240478
Molecular Formula:
C3H3NOS2
Molecular Weight:
133.19
MDL Number:
MFCD00005488
MOL File:
141-84-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:14:12
Product description Number Pack Size Price
Rhodanine 97% 118192 25g $61.5
Rhodanine 97% 118192 100g $133
Rhodanine >99.0%(T) R0017 25g $92
Rhodanine min. 98.0 % R0017 100G $230
Rhodanine >99.0%(T) R0017 500g $825
More product size

Rhodanine Properties

Melting point 165-169 °C(lit.)
Density 0.868
refractive index 1.5231 (estimate)
storage temp. -20°C
solubility methanol: soluble0.5g/10 mL, clear, colorless to greenish-yellow
form Fine Crystalline Powder
pka pK (25°) 5.52
color Light yellow to beige
Water Solubility SOLUBLE IN HOT WATER
Merck 14,8184
BRN 110701
InChI InChI=1S/C3H3NOS2/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
InChIKey KIWUVOGUEXMXSV-UHFFFAOYSA-N
SMILES S1CC(=O)NC1=S
CAS DataBase Reference 141-84-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 7O50LKL2G8
NIST Chemistry Reference 2-Thioxo-4-thiazolidinone(141-84-4)
EPA Substance Registry System Rhodanine (141-84-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P301+P312+P330-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-41
Safety Statements  22-26-39
RIDADR  3288
WGK Germany  3
RTECS  VI7700000
TSCA  TSCA listed
HazardClass  6.1(a)
PackingGroup  II
HS Code  29341000
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Hazardous Substances Data 141-84-4(Hazardous Substances Data)
NFPA 704
1
2 0

Rhodanine price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 118192 Rhodanine 97% 141-84-4 25g $61.5 2026-04-30 Buy
Sigma-Aldrich 118192 Rhodanine 97% 141-84-4 100g $133 2026-04-30 Buy
TCI Chemical R0017 Rhodanine >99.0%(T) 141-84-4 25g $92 2026-04-30 Buy
TCI Chemical R0017 Rhodanine min. 98.0 % 141-84-4 100G $230 2026-04-30 Buy
TCI Chemical R0017 Rhodanine >99.0%(T) 141-84-4 500g $825 2023-06-20 Buy
Product number Packaging Price Buy
118192 25g $61.5 Buy
118192 100g $133 Buy
R0017 25g $92 Buy
R0017 100G $230 Buy
R0017 500g $825 Buy

Rhodanine Chemical Properties,Uses,Production

Chemical Properties

light yellow to beige fine crystalline powder

Uses

thiadiazole pharmaceutical intermediate

Uses

In the synthesis of phenylalanine.

Uses

In the case of reagents containing several potential donor atoms, one of the first steps in the study of complex formation is the specification of the functional groups which actually participate in the complexation reaction. The literature on rhodanine derivatives provides a good example of such examinations.

Definition

ChEBI: Rhodanine is a thiazolidinone.

General Description

Light yellow crystals. Density 0.868 g / cm3. Melting point 168.5°C. May explode on rapid heating.

Air & Water Reactions

Water soluble.

Reactivity Profile

Rhodanine may generate hydrogen sulfide with acids. May generate heat and hydrogen gas with alkali metals, nitrides, hydrides, and other strong reducing agents.

Hazard

May explode when heated to 166C. Toxic by ingestion.

Biochem/physiol Actions

Rhodanine inhibits the multiplication of echovirus 12 and the development of virus-induced morphologic changes.

Purification Methods

Crystallise rhodanine from glacial acetic acid or water. It is used to estimate Ag and gallic acid [Thies & Fischer Microchimica Acta 809 1973]. [Beilstein 27 H 242, 27 I 309, 27 II 288, 27 III/IV 3188.]

Global( 309)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+8613336195806 sales@capot.com China 29640 60
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
career henan chemical co
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Alchem Pharmtech,Inc.
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Shenyang Simchoice Chemical Co.,Ltd
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CONIER CHEM AND PHARMA LIMITED
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Shanghai UCHEM Inc.
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ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
GLR Innovations
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View Lastest Price from Rhodanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Rhodanine pictures 2019-07-06 Rhodanine
141-84-4
US $8.00 / kg 1kg 99% 10MT Career Henan Chemical Co
  •  Rhodanine pictures
  • Rhodanine
    141-84-4
  • US $8.00 / kg
  • 99%
  • Career Henan Chemical Co
2,4-Thiazolidinedione, 2-thio- 2,4-thiazolidinedione,2-thio-[qr] 2-thio-4-ketothiazolidine[qr] 2-thio-4-thiazolidinedione 2-Thioxo-1,3-thiazolidin-4-one 2-thioxo-4-thiazolidinon 4-Oxo-2-thionothiazolidine 4-Oxo-2-thiothiazolidin 4-oxo-2-thiothiazolidin[czech][qr] 4-Oxo-2-thioxothiazoline 4-Thiazolidinone, 2-thioxo- 2-THIOXO-4-THIAZOLIDINONE 2-THIOXOTHIAZOLIDIN-4-ONE 2-THIOXO-1,3-THIAZOLAN-4-ONE AKOS BBS-00000851 AKOS B029032 TIMTEC-BB SBB000066 RHODANIC ACID RHODANILIC ACID RHODANINE 4-Thiazolidinone-2-thione~2-Thioxo-4-thiazolidinone Rhodanine, 98+% Rhodanine,2-Thioxo-4-thiazolidinone Rhodanine, synthesis grade Rhodanine 1.5g [141-84-4] 2-Thio-4-thiazolidine 4-Oxo-thiazolidine-2-thione Argenton 4-Oxo-1,3-thiazolidine-2-thione Rhodanine, 2-Thio-1,3-thiazolan-4-one Rhodanine,99% RHODANINERHODANINERHODANINE 4-Thiazolidinone-2-thione 4-thioxo-4-thiazolidone[qr] rhodanicacid[qr] Rhodanin rhodanin[czech][qr] Rhodaninic acid rhodaninicacid Rodanin USAF ha-2 usafha-2 usafha-2[qr] 2-THIO-4-KETOTHIAZOLIDINE 2-Thio-2,4-thiazolidinedione Rhodanine, 99% 25GR 2-Thio-2,4-thiazolidinedione 2-THIO-4-KETOTHIAZOLIDINE 2-THIOXO-1,3-THIAZOLAN-4-ONE 2-THIOXO-4-THIAZOLIDINONE 2-THIOXOTHIAZOLIDIN-4-ONE AKOS B029032 AKOS BBS-00000851 RHODANIC ACID RHODANILIC ACID RHODANINE 2-Thioxo-4-thiazolidinone for synthesis Rhodanine > Rhodanine (6CI, 8CI) RSOdanin Silver reagent 2-thiothiazolealkane-4-one 141-84-4 C3H3NOS2 IR/UV/ VIS Heterocyclic Building Blocks Spectroscopy Reagents