Rhodanine
- CAS No.
- 141-84-4
- Chemical Name:
- Rhodanine
- Synonyms
- 2-THIOXOTHIAZOLIDIN-4-ONE;Rhodanin;AKOS BBS-00000851;2-THIOXO-4-THIAZOLIDINONE;Rodanin;Argenton;usafha-2;RSOdanin;RHODANINE;USAF ha-2
- CBNumber:
- CB7240478
- Molecular Formula:
- C3H3NOS2
- Molecular Weight:
- 133.19
- MDL Number:
- MFCD00005488
- MOL File:
- 141-84-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 165-169 °C(lit.) |
|---|---|
| Density | 0.868 |
| refractive index | 1.5231 (estimate) |
| storage temp. | -20°C |
| solubility | methanol: soluble0.5g/10 mL, clear, colorless to greenish-yellow |
| form | Fine Crystalline Powder |
| pka | pK (25°) 5.52 |
| color | Light yellow to beige |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,8184 |
| BRN | 110701 |
| InChI | InChI=1S/C3H3NOS2/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6) |
| InChIKey | KIWUVOGUEXMXSV-UHFFFAOYSA-N |
| SMILES | S1CC(=O)NC1=S |
| CAS DataBase Reference | 141-84-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 7O50LKL2G8 |
| NIST Chemistry Reference | 2-Thioxo-4-thiazolidinone(141-84-4) |
| EPA Substance Registry System | Rhodanine (141-84-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P301+P312+P330-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 22-26-39 | |||||||||
| RIDADR | 3288 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VI7700000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29341000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
|||||||||
| Hazardous Substances Data | 141-84-4(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Rhodanine price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 118192 | Rhodanine 97% | 141-84-4 | 25g | $61.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 118192 | Rhodanine 97% | 141-84-4 | 100g | $133 | 2026-04-30 | Buy |
| TCI Chemical | R0017 | Rhodanine >99.0%(T) | 141-84-4 | 25g | $92 | 2026-04-30 | Buy |
| TCI Chemical | R0017 | Rhodanine min. 98.0 % | 141-84-4 | 100G | $230 | 2026-04-30 | Buy |
| TCI Chemical | R0017 | Rhodanine >99.0%(T) | 141-84-4 | 500g | $825 | 2023-06-20 | Buy |
Rhodanine Chemical Properties,Uses,Production
Chemical Properties
light yellow to beige fine crystalline powder
Uses
thiadiazole pharmaceutical intermediate
Uses
In the synthesis of phenylalanine.
Uses
In the case of reagents containing several potential donor atoms, one of the first steps in the study of complex formation is the specification of the functional groups which actually participate in the complexation reaction. The literature on rhodanine derivatives provides a good example of such examinations.
Definition
ChEBI: Rhodanine is a thiazolidinone.
General Description
Light yellow crystals. Density 0.868 g / cm3. Melting point 168.5°C. May explode on rapid heating.
Air & Water Reactions
Water soluble.
Reactivity Profile
Rhodanine may generate hydrogen sulfide with acids. May generate heat and hydrogen gas with alkali metals, nitrides, hydrides, and other strong reducing agents.
Hazard
May explode when heated to 166C. Toxic by ingestion.
Biochem/physiol Actions
Rhodanine inhibits the multiplication of echovirus 12 and the development of virus-induced morphologic changes.
Purification Methods
Crystallise rhodanine from glacial acetic acid or water. It is used to estimate Ag and gallic acid [Thies & Fischer Microchimica Acta 809 1973]. [Beilstein 27 H 242, 27 I 309, 27 II 288, 27 III/IV 3188.]
Rhodanine Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Shenyang Delier Biotechnology Co., Ltd. | 15942301471 15942301471 | 15942301471@163.cn | China | 114 | 58 |
| Shenyang yimoke chemical products co. LTD | 13998106873 | 297303255@qq.com | China | 150 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 94607 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
